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APOBEC3A Antibody, Biotin conjugated

  • 中文名稱:
    APOBEC3A兔多克隆抗體, Biotin偶聯(lián)
  • 貨號:
    CSB-PA001921LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) APOBEC3A Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    APOBEC3A
  • 別名:
    A3A antibody; ABC3A_HUMAN antibody; APOBEC3A antibody; Apolipoprotein B mRNA editing enzyme antibody; Apolipoprotein B mRNA editing enzyme; catalytic polypeptide like 3A antibody; ARP3 antibody; bK150C2.1 antibody; Catalytic polypeptide like 3A antibody; Phorbolin 1 antibody; Phorbolin-1 antibody; PHRBN antibody; Probable DNA dC >dU editing enzyme APOBEC-3A antibody; Probable DNA dC->dU-editing enzyme APOBEC-3A antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human DNA dC->dU-editing enzyme APOBEC-3A protein (1-199AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
  • 基因功能參考文獻:
    1. the APOBEC3A/B deletion polymorphism was not associated with risk of breast, lung, colon or prostate cancer in this Norwegian cohort PMID: 29140415
  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 蛋白家族:
    Cytidine and deoxycytidylate deaminase family
  • 組織特異性:
    Expressed in peripheral leukocytes with higher expression in CD14-positive phagocytic cells. Highly expressed in keratinocytes and in periphery blood monocytes. Also detected in non-lymphoid tissues including lung and adipose tissues. Found at high levels
  • 數(shù)據(jù)庫鏈接:

    HGNC: 17343

    OMIM: 607109

    KEGG: hsa:100913187

    STRING: 9606.ENSP00000249116

    UniGene: Hs.226307



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