在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

APBB2 Antibody

  • 中文名稱:
    APBB2兔多克隆抗體
  • 貨號:
    CSB-PA009249
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    APBB2
  • 別名:
    Amyloid beta (A4) precursor protein-binding; family B; member 2 (Fe65 like) antibody; Amyloid beta A4 precursor protein binding family B member 2 antibody; Amyloid beta A4 precursor protein-binding family B member 2 antibody; APBB 2 antibody; APBB2 antibody; APBB2_HUMAN antibody; Fe65 like 1 antibody; Fe65 like antibody; Fe65 like protein antibody; FE65L 1 antibody; FE65L antibody; FE65L1 antibody; Protein Fe65-like 1 antibody; Rirl 1 antibody; Rirl1 antibody; TR2 L antibody; TR2L antibody; Zfra antibody; Zinc finger like protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human Fe65L.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a role in the maintenance of lens transparency, and may also play a role in muscle cell strength. Involved in hippocampal neurite branching and neuromuscular junction formation, as a result plays a role in spatial memory functioning. Activates transcription of APP.
  • 基因功能參考文獻:
    1. APBB2 was differentially expressed between Fibromyalgia patients and healthy controls. PMID: 27157394
    2. results provide additional evidence of a genetic interaction between GSK3beta and APBB2 and further suggest that GSK3beta is involved in the pathophysiology of both of the primary neuropathologies of Alzheimer's disease PMID: 26194614
    3. The APBB2 rs13133980 G allele was over-represented in centenarians with severe cognitive impairment compared to individuals without this disability. PMID: 23384821
    4. FE65L1 potentiates gamma-secretase processing of APP CTFs. This requires binding of FE65L1 to APP and APP CTFs. Enhanced APP CTF processing can be detected in early endosome vesicles PMID: 14527950
    5. rs13133980 associated significantly with age of onset in Alzheimer disease. Genetic variations in APBB2 may affect late onset AD susceptibility. PMID: 15714520
    6. the apoptosis inhibitory domain of FE65-like protein 1 regulates both apoptotic and caspase-independent programmed cell death mediated by TNF PMID: 16083851
    7. In response to TNF, Zfra is upregulated and modulates TNF-mediated cell death via interacting with TRADD, FADD and RIP (death-inducing signaling complex) at the receptor level, and downstream effectors NF-kappaB, p53, WOX1, and JNK1. PMID: 17567906
    8. The hCV1558625 G allele was over-represented in patients with onset under age 70 compared to controls in the same age range. PMID: 18852029
    9. The differential processing of amyloid-beta precursor via secretase enzymes regulates the proliferation and differentiation of human embryonic stem cell. PMID: 19542221

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum. Golgi apparatus. Early endosome.
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 582

    OMIM: 602710

    KEGG: hsa:323

    STRING: 9606.ENSP00000427211

    UniGene: Hs.479602



主站蜘蛛池模板: 国产精品亚洲а∨无码播放| 免费国产成人高清在线观看网站| 国产又黄又潮娇喘视频在线观看| 无码中文字幕免费一区二区三区| 国内熟妇人妻色无码视频在线| 国产午夜福利精品一区| 国产精品系列无码专区| 暴力调教一区二区三区| 搡女人真爽免费视频大全| 色综合久久精品亚洲国产| 中文人妻无码一区二区三区| 国产一区二区精品久久岳| 国产福利高颜值在线观看| 又爽又黄又无遮挡网站| 欧美丰满美乳xxⅹ高潮www| 精品亚洲欧美无人区乱码| 成人国产一区二区三区| 日韩精品a片一区二区三区妖精| 成人区精品一区二区不卡| 日本免费一本一二区三区| 97久久草草超级碰碰碰| 成人动漫综合网| 亚洲成熟女人毛毛耸耸多| 亚洲欧美日韩二三区在线| 亚洲国产aⅴ综合网| 人妻av中文字幕无码专区| 暖暖 在线 日本 免费 中文| 亚洲性色av一区二区三区| 影音先锋日日狠狠久久| 日产精品久久久久久久蜜臀| 国模无码视频一区二区三区| 国内揄拍国产精品人妻门事件| 天天摸天天做天天爽天天弄| 亚洲日韩色欲色欲com| 精品久久久无码人妻中文字幕| 亚洲精品~无码抽插| 无码国产精品高清免费| 国产精品 欧美 亚洲 制服| 国产成人无码免费看片软件| 亚洲精品国产av成拍色拍个| 亚洲成αv人片在线观看|