在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

APBA2 Antibody

  • 中文名稱:
    APBA2兔多克隆抗體
  • 貨號:
    CSB-PA504012
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA504012(APBA2 Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA504012(APBA2 Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    APBA2
  • 別名:
    Adapter protein X11beta antibody; Amyloid beta A4 precursor protein-binding family A member 2 antibody; APBA2 antibody; APBA2_HUMAN antibody; D15S1518E antibody; HsT16821 antibody; LIN 10 antibody; MGC:14091 antibody; MGC99508 antibody; Mint 2 antibody; Mint-2 antibody; MINT2 antibody; Neuron-specific X11L protein antibody; Neuronal Munc18-1-interacting protein 2 antibody; Phosphotyrosine binding/interacting domain (PTB) bearing protein antibody; X11 beta antibody; X11 like protein antibody; X11l antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthetic peptide of Human APBA2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:100-1:300
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta.
  • 基因功能參考文獻:
    1. These results support the hypothesis that APBA2 gene expression in different areas of Alzheimer's patient's brains. PMID: 28164769
    2. Aberrant MINT2 methylation in body fluids may predict peritoneal micrometastasis for gastric cancer (GC) patients, which is a potential poor prognostic factor in GC. PMID: 24385013
    3. a significant difference was shown for APBA2 gene expression of peripheral lymphocytes between Chinese Han Tourette syndrome (TS) group and healthy controls idicating the APBA2 gene is a promising peripheral blood biomarker that discriminates between patients with TS and healthy subjects PMID: 23076970
    4. Amyloid beta A4 precursor protein-binding family A member 2 contains a potent neuronal promoter whose activity may be regulated by DNA methylation and glucocorticoid receptor [alpha], paired box protein 5. PMID: 22222501
    5. The co-occurrence of two nonsynonymous mutations in both affected siblings in a single family, each transmitted from a different unaffected parent, suggest a role for APBA2 mutations in rare individuals with ASD. PMID: 20029827
    6. APBA2 were genes activated in early endometrial endometrioid carcinoma (stages I-II). PMID: 20015385
    7. X11beta-mediated reduction in cerebral Abeta is associated with cognition and long-term potentiation in Alzheimer's disease APPswe transgenic mice. PMID: 19744962
    8. Interaction of transcriptional coactivators with Mint1 or Mint2 prevents nuclear localization and transactivation of the transduction network mediated by amyloid precursor protein. PMID: 20016085
    9. The APBA2 gene has been found to map to a more telomeric location in chromosome 15q13 than previously found, and is partially duplicated within the broader region located approximately 5 Mb distal to the intact locus. PMID: 12720574
    10. hXB51 isoforms regulate Abeta generation differently, either enhancing it by modifying the association of X11L with APP or suppressing it in an X11L-independent manner PMID: 12780348
    11. This protein, which is a member of the mammalian LIN-10 protein family and a possible regulator of Abeta production, elevated APP and APLP2 phosphorylation PMID: 14970211
    12. Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. PMID: 17989066
    13. Phosphorylation of amino acids Ser236 and Ser238 in the X11L regulatory region are critical for increasing association of X11L and amyloid beta-protein precursor and are conserved in X11, a neuronal X11 family protein, but not in non-neuronal X11L2. PMID: 19222704

    顯示更多

    收起更多

  • 組織特異性:
    Brain.
  • 數據庫鏈接:

    HGNC: 579

    OMIM: 602712

    KEGG: hsa:321

    STRING: 9606.ENSP00000453144

    UniGene: Hs.618112



主站蜘蛛池模板: 看成年女人午夜毛片免费| 免费人成网站在线观看欧美| 国产无遮挡裸体免费视频| 一区二区无码免费视频网站| 国产在线观看免费观看不卡| 在线无码av一区二区三区| 国产公开免费人成视频| 国产精品v欧美精品v日韩精品| 久久久无码中文字幕久...| 国产精品亚洲成在人线| 又湿又紧又大又爽又a视频| 精品一区二区成人精品| 无码人妻一区二区三区av| 在线a亚洲视频播放在线观看| 娇小萝被两个黑人用半米长| 日韩一卡二卡三卡四卡免费观在线| 成人无遮挡18禁免费视频| 狠狠色噜噜狠狠狠狠777米奇小说| 成年女人免费视频播放体验区 | 欧美自拍另类欧美综合图片区| av在线播放日韩亚洲欧| 久久精品国产精品亚洲下载| 中文无码伦av中文字幕在线| 夜夜天天噜狠狠爱2019| 国产精品美女久久久网站 | 国产在线观看www污污污| 国产精品久久久福利| 刺激一区仑乱| 无码精品a∨在线观看无广告| 同性女女黄h片在线播放| 国产剧情无码播放在线看| 成在线人视频免费视频| 性人久久网av| 国产精品无打码在线播放| 先锋影音av最新资源| 国产人成无码视频在线观看| 国产在线精品一区二区不卡麻豆| 国产精品亚洲综合久久系列| 97熟女毛毛多熟妇人妻aⅴ | 18禁裸男晨勃露j毛免费观看| 欧美黑人与白人精品a片|