在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

AP1M1 Antibody

  • 中文名稱:
    AP1M1兔多克隆抗體
  • 貨號(hào):
    CSB-PA863146ESR1HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: AP1M1 antibody at 1.43µg/ml
      Lane 1: A375 whole cell lysate
      Lane 2: Jurkat whole cell lysate
      Lane 3: Hela whole cell lysate
      Lane 4: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 49, 50 kDa
      Observed band size: 49 kDa
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA863146ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA863146ESR1HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) AP1M1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    AP1M1
  • 別名:
    Adaptor protein complex AP-1 mu-1 subunit antibody; Adaptor-related protein complex 1 mu-1 subunit antibody; AP-1 complex subunit mu-1 antibody; AP-mu chain family member mu1A antibody; Ap1m1 antibody; AP1M1_HUMAN antibody; AP47 antibody; CLAPM2 antibody; Clathrin adaptor protein AP47 antibody; Clathrin assembly protein complex 1 medium chain 1 antibody; Clathrin assembly protein complex 1 medium chain antibody; Clathrin assembly protein complex AP1 mu subunit antibody; Clathrin coat assembly protein AP47 antibody; Clathrin coat-associated protein AP47 antibody; CLTNM antibody; Golgi adaptor AP 1 47 kDa protein antibody; Golgi adaptor HA1/AP1 adaptin mu-1 subunit antibody; HA1 47 kDa subunit antibody; MU 1A antibody; Mu-adaptin 1 antibody; Mu1A-adaptin antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human AP-1 complex subunit mu-1 protein (1-160AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
  • 基因功能參考文獻(xiàn):
    1. found 31 ORF9p interaction partners, among which was AP1M1, the mu subunit of the adaptor protein complex 1 (AP-1). AP-1 is a heterotetramer involved in intracellular vesicle-mediated transport and regulates the shuttling of cargo proteins between endosomes and the trans-Golgi network via clathrin-coated vesicles. PMID: 29793951
    2. Acidic clusters act as sorting signals for packaging cargo into clathrin-coated vesicles (CCVs), and also facilitate down-regulation of MHC-I by HIV-1 Nef. The basic patch on micro1 that interacts with the Nef acidic cluster also contributes to the binding of endogenous acidic cluster proteins. PMID: 28743825
    3. CNNM4 is sorted to the basolateral membrane by the complementary function of AP-1A and AP-1B PMID: 25449265
    4. Adaptor protein 1 promotes cross-presentation through the same tyrosine signal in major histocompatibility complex class I as that targeted by HIV-1. PMID: 23678182
    5. IRS-1 associates with mu1A of the ubiquitously expressed AP-1 complex through three protein interaction motifs. PMID: 23478262
    6. Mu1A binding to the N terminus of HIV-1 Nef determines its ability to downregulate major histocompatibility complex class I in T lymphocytes. PMID: 22301137
    7. AP-1 mu1A is involved in the kAE1 trafficking of kidney alpha-intercalated cells PMID: 20833140
    8. These data identify the micro subunit of AP-1 (micro1) as the key target of the MHC-I CD/Nef complex, and they indicate that both Y320 in the MHC-I CD and E62-65 in Nef interact directly with micro1. PMID: 18057255

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
  • 蛋白家族:
    Adaptor complexes medium subunit family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 13667

    OMIM: 603535

    KEGG: hsa:8907

    STRING: 9606.ENSP00000388996

    UniGene: Hs.71040



主站蜘蛛池模板: 成人午夜福利视频后入| 亚洲—本道 在线无码av发| 最新国产精品久久精品| 久热国产精品视频一区二区三区| 麻豆av福利av久久av| 伊人久久精品在热线热| 成人午夜无码精品免费看| 精品一区二区三区在线观看| 精品影片在线观看的网站| 日产幕无线码三区在线| 18禁止观看强奷免费国产大片| 日韩精品久久久久久免费| 国产妇女馒头高清泬20p多毛| 亚洲人av在线无码影院观看| 日韩av无码中文无码电影| 欧洲熟妇色xxxx欧美老妇软件 | 国产成人一区二区三区app| 四川丰满妇女毛片四川话| 久久婷婷五月综合97色直播| 内射视频←www夜| 99久久99久久精品免费观看| 亚洲熟妇av日韩熟妇在线| 日本护士毛茸茸xx| 久久天天躁狠狠躁夜夜96流白浆| 99久久99久久精品免费看蜜桃| 强伦人妻一区二区三区视频18| 日韩人妻潮喷中文在线视频| 性欧美老妇另类xxxx| 国产午夜无码视频在线观看| 亚洲日韩性欧美中文字幕| 欧美丰满美乳xxⅹ高潮www| 欧美性白人极品hd| 亚洲中文字幕婷婷在线| 精品国产免费人成电影在线看| 无卡无码无免费毛片| 无码人妻丰满熟妇区五十路| 在线天堂资源www在线污| 亚洲精品一区久久久久久| 山东熟女啪啪哦哦叫| 久久久久久久精品成人执小说一白| 女人扒开屁股爽桶30分钟|