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AP1B1 Antibody

  • 中文名稱:
    AP1B1兔多克隆抗體
  • 貨號:
    CSB-PA070672
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA070672(AP1B1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA070672(AP1B1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    AP1B1
  • 別名:
    Adaptin; beta 2 (beta) antibody; Adaptor protein complex AP-1 subunit beta-1 antibody; Adaptor related protein complex 1; beta 1 subunit antibody; Adaptor related protein complex 2; beta 1 subunit antibody; Adaptor-related protein complex 1 subunit beta-1 antibody; ADTB1 antibody; ADTB2 antibody; AP 1 complex subunit beta 1 antibody; AP 2 complex subunit beta 1 antibody; AP-1 complex subunit beta-1 antibody; AP1 Beta antibody; AP1B1 antibody; AP1B1_HUMAN antibody; AP2 Beta antibody; AP2B1 antibody; Beta-1-adaptin antibody; Beta-adaptin 1 antibody; Beta1 adaptin antibody; Beta2 adaptin antibody; CLAPB1 antibody; CLAPB2 antibody; Clathrin assembly protein complex 1 beta large chain antibody; Golgi adaptor HA1/AP1 adaptin beta subunit antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthetic peptide of Human AP1B1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    IHC 1:100-1:300
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
  • 基因功能參考文獻:
    1. both ubiquitous (AP-1A) and epithelium-specific (AP-1B) forms of the tetrameric clathrin adaptor AP-1 are capable of carrying out basolateral sorting of ClC-2. PMID: 25739457
    2. AP1B regulates basolateral EGFR membrane delivery predominantly in the biosynthetic route in MDCK cells monolayers. PMID: 23205726
    3. The conclude that in addition to its role in endocytosis, ARH cooperates with AP-1B in basolateral exocytosis of LDLR from recycling endosomes. PMID: 21444685
  • 亞細胞定位:
    Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
  • 蛋白家族:
    Adaptor complexes large subunit family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 554

    OMIM: 600157

    KEGG: hsa:162

    STRING: 9606.ENSP00000350199

    UniGene: Hs.368794



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