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  4. AOAH Antibody

AOAH Antibody

  • 中文名稱：
    AOAH兔多克隆抗體
  • 貨號：
    CSB-PA001853LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in:Mouse Brain tissue lysate
      All lanes: AOAH antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 66 kDa
      Observed band size: 66 kDa
    • IHC image of CSB-PA001853LA01HU diluted at 1:100 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody
  • 其他：

產品詳情

  • 產品描述：

    CUSABIO produces the product (CSB-PA623900LA01HU) by immunizing rabbits with the peptide corresponding to amino acids 131-332 of the recombinant human LRP8. The anti-LRP8 antibody is eventually purified from rabbit antiserum by protein G affinity chromatography. Its purity is greater than 95%. It occurs as an unconjugated IgG. And it only reacts with human LRP8 protein. This LRP8 polyclonal antibody is suitable for the detection of LRP8 protein in ELISA, WB, and IF applications.

    The LRP8 protein, also known as apolipoprotein E receptor 2 (APOER2), regulates the uptake and clearance of lipoproteins and mediates signaling events in response to extracellular ligands, with important implications for brain development and function, as well as for metabolic disorders and neurodegenerative diseases.

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) AOAH Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    AOAH
  • 別名：
    Acyloxyacyl hydrolase (neutrophil) antibody; Acyloxyacyl hydrolase large subunit antibody; AOAH antibody; AOAH_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Acyloxyacyl hydrolase protein (180-254AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，AOAH Antibody (CSB-PA001853LA01HU)，的標記方式是Non-conjugated。對于AOAH Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA001853LB01HU AOAH Antibody, HRP conjugated ELISA
    FITC CSB-PA001853LC01HU AOAH Antibody, FITC conjugated
    Biotin CSB-PA001853LD01HU AOAH Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    Application:ELISA, Mouse(WB),Human(IHC)
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:50-1:200
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides. By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses. In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria.
  • 基因功能參考文獻：
    1. analysis of AOAH function through its crystal structure and complex with lipopolysaccharide PMID: 29343645
    2. AOAH - Gene involved in innate immunity that have been associated with Chronic Rhinosinusitis. PMID: 27888910
    3. AOAH rs60023210 variants may be associated with carotid intima-media thickness at bifurcation. PMID: 26319989
    4. Polymorphisms in RYBP and AOAH genes are associated with chronic rhinosinusitis in a Chinese population. PMID: 22723975
  • 亞細胞定位：
    Secreted. Cytoplasmic vesicle.
  • 數據庫鏈接：

    HGNC: 548

    OMIM: 102593

    KEGG: hsa:313

    STRING: 9606.ENSP00000258749

    UniGene: Hs.488007



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