在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ANXA11 Antibody

  • 中文名稱:
    ANXA11兔多克隆抗體
  • 貨號:
    CSB-PA001838GA01HU
  • 規格:
    ¥3,900
  • 圖片:
    • Western Blot
      Positive WB detected in: Hela whole cell lysate
      All lanes: ANXA11 antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 54 kDa
      Observed band size: 54 kDa
      Exposure time: 5s
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ANXA11
  • 別名:
    56 kDa autoantigen antibody; Annexin A11 antibody; Annexin XI antibody; Annexin-11 antibody; AnnexinA11 antibody; AnnexinXI antibody; ANX 11 antibody; ANX A11 antibody; ANX11 antibody; ANX11_HUMAN antibody; ANXA 11 antibody; ANXA11 antibody; Autoantigen 56 kD antibody; Calcyclin associated annexin 50 antibody; Calcyclin-associated annexin 50 antibody; CAP 50 antibody; CAP-50 antibody; CAP50 antibody; OTTHUMP00000059806 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Annexin A11 protein (1-175AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Binds specifically to calcyclin in a calcium-dependent manner. Required for midbody formation and completion of the terminal phase of cytokinesis.
  • 基因功能參考文獻:
    1. Both ANXA11 G38R protein and ANXA11 D40G protein showed a shorter half-life than ANXA11 wild type protein, while there was no difference between ANXA11 G38R protein and ANXA11 D40G protein. There was no visible insoluble substance in the NP-40 lysates for ANXA11 wild type protein, ANXA11 G38R protein and ANXA11 D40G protein. G38R and D40G mutations reduce the stability of ANXA11 protein. PMID: 30109997
    2. Genetic variants in RAB23 and ANXA11 genes were associated with an increased risk of sarcoidosis-associated uveitis. PMID: 29416296
    3. ANXA11 plays a critical role in regulating gastric cancer proliferation, migration, and invasion. PMID: 29306955
    4. Data conclude that mutations in ANXA11 are associated with ALS and implicate defective intracellular protein trafficking in disease pathogenesis. PMID: 28469040
    5. Letter: ANXA11 SNPs increase susceptibility to fibrosing sarcoiodosis in African Americans. PMID: 28079857
    6. Review/Meta-analysis: ANXA11 SNP rs2573346 and rs2789679 conferred protection against sarcoidosis. SNP rs1049550 may be a risk factor for sarcoidosis in overall population. PMID: 27537711
    7. ANXA11 rs1049550 and PPP1R15A rs557806 may improve the identification of mCRC patients sensitive to bevacizumab regimens, and further validation is required in large cohorts PMID: 27177629
    8. These findings point to a role for the polymorphisms of ANXA11 in sarcoidosis in a Chinese Han population, and may be informative for future genetic studies on sarcoidosis. PMID: 25056970
    9. findings suggest that AnxA11 maintains architectural and functional features of the ERES by coordinating with ALG-2 to stabilize Sec31A at the ERES. PMID: 25540196
    10. the associations of Anxa11 with Ca(2+)-regulated exocytosis, cytokinesis, sex differentiation, autoimmune diseases, thrombolysis and cancers are summarized--{REVIEW} PMID: 24508622
    11. Annexin A11 rs1049550*T allele exerts a significant protective effect on sarcoidosis susceptibility. PMID: 24032725
    12. LIFR rs3729740 and possibly ANXA11 rs1049550 may be useful as biomarkers for predicting whether metastatic colorectal cancer patients are sensitive to relevant target regimens, although further validation in large cohorts is needed. PMID: 23579219
    13. ANXA11 SNPs are associated with sarcoidosis in African Americans. PMID: 23151485
    14. ANXA11 rs1049550 single nucleotide polymorphism is the susceptibility marker in sarcoidosis, at least in Caucasians. PMID: 21562576
    15. Data confirm the strong association between variations in ANXA11 and sarcoidosis and support the hypothesis that ANXA11 represents a strong genetic risk factor for sarcoidosis. PMID: 20805159
    16. analysis of the sarcoidosis-associated variant of annexin A11 PMID: 20093723
    17. Pro/Gly/Tyr/Ala-rich hydrophobic region in AnxN masked the Ca(2+)-dependently exposed hydrophobic surface of ALG-2. PMID: 11883939
    18. The penta-EF-hand domain of ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca2+-dependent manner. PMID: 12445460
    19. calcium- and cell cycle-dependent association with the nuclear envelope PMID: 12601007
    20. annexin XI associates with the mitotic spindles and might play a role in cell division PMID: 12805373
    21. Annexin 11-depleted cells failed to complete cytokinesis and died by apoptosis, demonstrating an essential role for annexin 11. PMID: 15197175
    22. The strongest association signal maps to the ANXA11 (annexin A11) gene on chromosome 10q22.3. PMID: 19165924
    23. Immunohistochemistry analyses indicated that annexin A11 immunointensity inversely correlated with HMOX1 immunoreactivity in 142 ovarian cancer patients. PMID: 19484149

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Melanosome. Nucleus envelope. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle.
  • 蛋白家族:
    Annexin family
  • 數據庫鏈接:

    HGNC: 535

    OMIM: 602572

    KEGG: hsa:311

    STRING: 9606.ENSP00000265447

    UniGene: Hs.530291



主站蜘蛛池模板: 躁躁躁日日躁| 午夜福利理论片高清在线观看| 亚洲日韩欧美国产高清αv| 精品国产一区二区三区四区五区| 午夜男女无遮挡拍拍视频| 亚洲 制服丝袜 中文字幕 在线| 国产成人无码精品久久涩吧| 国产美女久久久亚洲综合| 欧美牲交a欧美牲交aⅴ免费真| 人禽无码视频在线观看| 欧美又粗又大又黄的片| 国产边摸边吃奶边叫做激情视频| 777午夜福利理论电影网| 国产精品自在在线午夜出白浆| 男女又色又爽又爽视频| 18禁超污无遮挡无码免费网站国产 | 国产亚洲精品久久久久久无几年桃 | 亚洲欧美国产国产一区二区三区 | 国产美女裸身网站免费观看视频| 欧美日韩在大午夜爽爽影院| 亚洲精品久久久久久一区二区| 久久www色情成人免费| 免费观看国产小粉嫩喷水| 无码大潮喷水在线观看| 久久人妻av一区二区软件 | 色噜噜亚洲男人的天堂www| 久久九九久精品国产免费直播| 亚洲中文字幕无码爆乳| 国产日产欧产精品精品蜜芽 | 日本视频免费高清一本18| 人妻无码精品久久亚瑟影视 | 国产又粗又猛又大爽老大爷| 国产色青青视频在线观看撒| 国产 | 欧洲野花视频天堂视频p| 日本精品人妻无码77777| 大陆熟妇丰满多毛xxxⅹ| 亚欧成人中文字幕一区| 青青草原精品99久久精品66| 国产激情无码一区二区| 2021最新精品国自产拍视频| 亚洲第一福利网站在线观看|