在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ANO2 Antibody, Biotin conjugated

  • 中文名稱:
    ANO2兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA885689LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ANO2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ANO2
  • 別名:
    Ano2 antibody; ANO2_HUMAN antibody; Anoctamin 2 antibody; Anoctamin-2 antibody; C12orf3 antibody; Chromosome 12 open reading frame 3 antibody; DKFZp434P102 antibody; Transmembrane protein 16B (eight membrane-spanning domains) antibody; Transmembrane protein 16B antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Anoctamin-2 protein (1-83AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
  • 基因功能參考文獻:
    1. residues facing the putative channel pore are responsible both for controlling the ion selectivity and the gating of the channel, providing an initial understanding of molecular mechanism of ion permeation in TMEM16B PMID: 28046119
    2. data revealed prominently increased autoantibody reactivity against the chloride-channel protein anoctamin 2 (ANO2) in multiple sclerosis cases compared with controls PMID: 26862169
    3. Olfactory function impairment in Italian patients with type 3 von Willebrand disease with partial deletion of TMEM16B. PMID: 25635880
    4. ANO2 is present in human myometrium. PMID: 24928056
    5. The third intracellular loop of TMEM16B is the site involved in calcium ion sensitivity, whereas the C-terminal part affects the rate of transition between the open and the closed state of the channel. PMID: 23570556
    6. VWF and TMEM16B deletions may have a role in severe von Willebrand disease type 3 PMID: 17371490
    7. This study suggested that TMEM16B to be a strong candidate for the long sought-after Ca(2+)-dependent chloride channel in the photoreceptor synapse. PMID: 19474308
    8. Ano2 likely amplifies the odor-induced generator potential in olfactory sensory neuron cilia by sensing elevated calcium levels, permitting the outward flow of chloride ions from the cell. PMID: 19561302
    9. C12orf3, FLJ10261 (ORAOV2), C11orf25 and FLJ34272 constitute a family of eight-transmembrane proteins with N- and C-terminal tails facing the cytoplasm. PMID: 12739008

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Anoctamin family
  • 組織特異性:
    Retina, especially in the photoreceptor synaptic terminals.
  • 數據庫鏈接:

    HGNC: 1183

    OMIM: 610109

    KEGG: hsa:57101

    STRING: 9606.ENSP00000314048

    UniGene: Hs.148970



主站蜘蛛池模板: 亚洲无人区午夜福利码高清完整版 | √天堂8资源中文在线| 99久久99久久精品国产片果冻| 国产成人无码专区| 亚洲成av人在线视猫咪| 免费网站看v片在线18禁无码| 亚洲中字幕日产av片在线| 大肉大捧一进一出好爽视频mba | 免费国产成人高清在线观看网站| 亚洲男人的天堂在线aⅴ视频| 国产午夜亚洲精品午夜鲁丝片| 精品国内自产拍在线观看视频| 玩弄少妇的肉体k8经典| 亚洲乱码伦av| 成在线人av免费无码高潮喷水 | 人妻少妇av无码一区二区| 亚洲视频无码高清在线| 色婷婷av一区二区三区浪潮| 欧美激情视频一区二区三区免费| 久久久久人妻一区精品色欧美 | 亚洲精品高清无码视频| 国产一区二区精品久久岳| 亚洲欧美日本韩国| 成年轻人电影免费无码| 亚洲色中文字幕无码av| 免费看少妇作爱视频| 狼人大香伊蕉国产www亚洲| 最近中文字幕免费大全在线| 国产精品视频免费一区二区| 日日噜噜噜夜夜爽爽狠狠| 国产精品成人网站| 欧美熟妇乱子伦xx视频| 精品国产一区二区三区免费| 欧洲乱码伦视频免费| 亚洲人成无码www久久久| 欧美牲交视频免费观看| 日本熟妇厨房bbw| 成人做爰69片免费看网站| 亚洲熟女精品中文字幕| 麻豆果冻精东九一传媒mv| 中文字幕在线影视|