在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ANO2 Antibody, Biotin conjugated

  • 中文名稱:
    ANO2兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA885689LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ANO2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ANO2
  • 別名:
    Ano2 antibody; ANO2_HUMAN antibody; Anoctamin 2 antibody; Anoctamin-2 antibody; C12orf3 antibody; Chromosome 12 open reading frame 3 antibody; DKFZp434P102 antibody; Transmembrane protein 16B (eight membrane-spanning domains) antibody; Transmembrane protein 16B antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Anoctamin-2 protein (1-83AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
  • 基因功能參考文獻:
    1. residues facing the putative channel pore are responsible both for controlling the ion selectivity and the gating of the channel, providing an initial understanding of molecular mechanism of ion permeation in TMEM16B PMID: 28046119
    2. data revealed prominently increased autoantibody reactivity against the chloride-channel protein anoctamin 2 (ANO2) in multiple sclerosis cases compared with controls PMID: 26862169
    3. Olfactory function impairment in Italian patients with type 3 von Willebrand disease with partial deletion of TMEM16B. PMID: 25635880
    4. ANO2 is present in human myometrium. PMID: 24928056
    5. The third intracellular loop of TMEM16B is the site involved in calcium ion sensitivity, whereas the C-terminal part affects the rate of transition between the open and the closed state of the channel. PMID: 23570556
    6. VWF and TMEM16B deletions may have a role in severe von Willebrand disease type 3 PMID: 17371490
    7. This study suggested that TMEM16B to be a strong candidate for the long sought-after Ca(2+)-dependent chloride channel in the photoreceptor synapse. PMID: 19474308
    8. Ano2 likely amplifies the odor-induced generator potential in olfactory sensory neuron cilia by sensing elevated calcium levels, permitting the outward flow of chloride ions from the cell. PMID: 19561302
    9. C12orf3, FLJ10261 (ORAOV2), C11orf25 and FLJ34272 constitute a family of eight-transmembrane proteins with N- and C-terminal tails facing the cytoplasm. PMID: 12739008

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Anoctamin family
  • 組織特異性:
    Retina, especially in the photoreceptor synaptic terminals.
  • 數據庫鏈接:

    HGNC: 1183

    OMIM: 610109

    KEGG: hsa:57101

    STRING: 9606.ENSP00000314048

    UniGene: Hs.148970



主站蜘蛛池模板: 人人妻人人澡人人爽欧美一区| 国产精品久久久久久52avav| 国产午夜亚洲精品国产成人小说| 久久国产36精品色熟妇| 国产av国内精品jk制服| 中文人妻av大区中文不卡| 无码午夜福利片| 97久久精品无码一区二区天美| 少妇伦子伦精品无码styles | 日本亚洲国产一区二区三区| 欧洲美女黑人粗性暴交| 免费又黄又爽又色的视频| 亚洲国产综合无码一区| 久久男人av资源网站| 亚洲一区在线观看尤物| 国产精品久久久久久妇女6080| 欧美熟妇丰满肥白大屁股免费视频| 国产男女猛烈视频在线观看| 精品国产一区二区三区久久久狼| 看曰本女人大战黑人视频| 桃花综合久久久久久久久久网| 成人伊人亚洲人综合网| 久久不见久久见免费视频7| 小泽玛莉亚一区二区视频在线| 一本久久伊人热热精品中文字幕 | 天堂网www在线资源最新版| 欧美写真视频在线观看| 国产黄a三级三级三级av在线看| 国产黄网永久免费视频大全| 亚洲国产精品无码中文字| 午夜精品久久久久久久喷水| 少妇做爰免费视看片| 亚洲丁香婷婷综合久久| 少妇愉情理伦片bd| 久久国产36精品色熟妇| 男人的天堂av社区在线| 我的性奴的肉玩具1一17心奴| 亚洲熟女乱色综合亚洲图片 | 少妇乳大丰满在线播放| 国产玉足榨精视频在线观看 | 精品少妇无码一区二区三批|