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  4. AMTN Antibody

AMTN Antibody

  • 中文名稱：
    AMTN兔多克隆抗體
  • 貨號：
    CSB-PA001685LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA001685LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) AMTN Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    AMTN
  • 別名：
    Amelotin antibody; Amtn antibody; AMTN_HUMAN antibody; RSTI689 antibody; UNQ689 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Amelotin protein (17-209AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，AMTN Antibody (CSB-PA001685LA01HU)，的標記方式是Non-conjugated。對于AMTN Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA001685LB01HU AMTN Antibody, HRP conjugated ELISA
    FITC CSB-PA001685LC01HU AMTN Antibody, FITC conjugated
    Biotin CSB-PA001685LD01HU AMTN Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis.
  • 基因功能參考文獻：
    1. TNF-alpha stimulates AMTN gene transcription in human gingival epithelial cells via C/EBP1, C/EBP2, and YY1 elements in the human AMTN gene promoter. PMID: 29282478
    2. Results show that AMTN and KLK4 are not essential for biological processes outside of the dentition or during the secretory stage of amelogenesis. Both KLK4 and AMTN proved to be essential for the maturation of dental enamel, a process that requires the removal of extracellularmatrix proteins and the deposition of ions on the sides of enamel crystallites. PMID: 26620968
    3. This study demonstrates for the first time that AMTN mutations cause non-syndromic human Amelogenesis imperfecta (AI) and explores the human phenotype, comparing it with that of mice with disrupted Amtn function. PMID: 27412008
    4. AMTN has a direct influence on biomineralization by promoting hydroxyapatite mineralization. PMID: 25407797
    5. proinflammatory cytokines induce Amelotin gene transcription and a role for Amelotin in gingival inflammation PMID: 25158173

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  • 相關疾病：
    Amelogenesis imperfecta 3B (AI3B)
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Amelotin family
  • 數據庫鏈接：

    HGNC: 33188

    OMIM: 610912

    KEGG: hsa:401138

    STRING: 9606.ENSP00000341013

    UniGene: Hs.453069



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