在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ALPP Antibody

  • 中文名稱:
    ALPP兔多克隆抗體
  • 貨號:
    CSB-PA001632ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: Alkaline phosphatase, placental type antibody at 8μg/ml
      Lane 1: A549 whole cell lysate
      Lane 2: Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 58 kDa
      Observed band size: 58 kDa
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA001632ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ALPP Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    ALPP; PLAP; Alkaline phosphatase, placental type; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; PLAP-1
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Alkaline phosphatase, placental type protein (260-520AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Alkaline phosphatase that can hydrolyze various phosphate compounds.
  • 基因功能參考文獻:
    1. This meta-analysis suggests that high serum ALP level is obviously associated with lower OS rate in patients with osteosarcoma, and it is an effective biomarker of prognosis. PMID: 29970708
    2. Concentrations of PLAP were elevated in gingival crevicular fluid of patients with pre-eclampsia. PMID: 26988336
    3. SALL4 also outperformed PLAP on a small sample of cytology blocks. Although SALL4 is not entirely specific, it is a highly sensitive marker with strong diffuse nuclear reactivity in the majority of MGCTs in the posttreatment setting, at significantly higher levels than PLAP PMID: 25906119
    4. Quantum-mechanical computational methods were employed to study the catalytic mechanism of human placental AP (PLAP). An active-site model was used, constructed on the basis of the X-ray crystal structure of the enzyme. PMID: 25409280
    5. term placental explants, but not their conditioned medium, can de-phosphorylate IGFBP-1 through the action of placental alkaline phosphatase PMID: 24856042
    6. Anti-PLAP antibodies may serve as a modular building blocks for the development of targeted therapeutic products, armed with cytotoxic drugs, radionuclides or cytokines as payloads. PMID: 24247025
    7. A candidate gene, ALPP, encoding the placental alkaline phosphatase, was identified as being potentially involved in recurrent spontaneous abortion. PMID: 24296104
    8. The objective of the following study was to record the specificity and sensitivity of alpha5(IV) loss, smoothelin expression and PLAP expression as markers of gastrointestinal smooth muscle neoplasms PMID: 24043717
    9. Data indicate that p180 is required for the efficient targeting of placental alkaline phosphatase (ALPP) mRNA to the endoplasmic reticulum (ER). PMID: 24019514
    10. Calculation of the electrostatic potentials within the active site of human placental alkaline phosphatase also suggests that the local positive electrostatic environment may account for its capability to distinguish various substrates PMID: 21910833
    11. High serum alkaline phosphatase cooperating with MMP-9 is associated with metastasis in patients with primary osteosarcoma. PMID: 22333159
    12. PLAP exerts a positive effect on DNA replication and acts as a proliferative factor in trophoblastic cells. PMID: 21868091
    13. The proximity of undifferentiated gonadal tissue with the tumors as well as the immunostaining patterns (PLAP+, OCT3/4+, and CD117/KIT+) suggests that germ cells found in them are a risk factor for gonadal tumors. PMID: 21692598
    14. the catalytic mechanism of human placental alkaline phosphatase PMID: 21939286
    15. Data show that serum alkaline phosphatase, Gleason score, and intensity of bone metastasis are important and statistically significant prognostic factors, and affects time to progression and life time. PMID: 19450995
    16. at a certain time point during adrenocortical development, some fetal zone cells survive owing to defective apoptosis and develop into childhood ACT, maintaining some characteristics of the embryonal period, such as PLAP expression PMID: 21516013
    17. Serum total calcium (r -0.1362, p<0.001), serum inorganic phosphate (r -0.45, p<0.001) and serum alkaline phosphatase (r -0.5587, p<0.001) have shown inverse relationship with age. PMID: 20655896
    18. High serum alkaline phosphatase is associated with chronic kidney disease. PMID: 20299338
    19. differential expression of Pl(1) and Pl(2) probably results from linkage disequilibrium with the sequence variation rs2014683G>A in the ALPP gene promoter that was shown to have allele-specific binding patterns to placental nuclear proteins. PMID: 20663553
    20. structure of placental alkaline phosphatase with pNPP contained only p-nitrophenol in three distinct sites, while the structure with 5'-AMP contained the p-nitrophenyl group in two of the sites instead of 5'-AMP PMID: 20693656
    21. Low magnitudes of tensile strain enhance expression of alkaline phosphatase in human osteoblasts. PMID: 19595020
    22. The PLAP D allele contains two amino acid substitutions: P209R (692C>G) and E429G (1352 A>G). PMID: 11857742
    23. Proximity of the protein moiety of a GPI-anchored protein to the membrane surface: a FRET study. PMID: 12081485
    24. the beta-N-acetylglucosaminyl phosphate diester residue is attached to the glycosylphosphatidylinositol anchor of human placental alkaline phosphatase and is a target of the channel-forming toxin aerolysin PMID: 12851398
    25. receptor for Aeromonas sobria hemolysin. PMID: 15715171
    26. analysis of human placental alkaline phosphatase in complex with functional ligands PMID: 15946677
    27. The effect of parity on placental weight and birth weight is examined through a series of birth records from an Indian population in Calcutta. PMID: 16431676
    28. crystal structure of strontium-substituted human placental alkaline phosphatase shows that strontium substitutes the calcium ion with concomitant modification of the metal coordination PMID: 16815919
    29. activity of GPI-anchored enzymes may be modulated by membrane microenvironment features PMID: 18416535
    30. Serum bilirubin, alkaline phosphatase, and aspartate aminotransferase are an efficient set of biochemistries to identify UDCA-treated patients with primary biliary cirrhosis at risk of death or liver transplantation (LT). PMID: 18752324
    31. Elevations of alkaline phosphatase is associated with therapy related pediatric cancer. PMID: 18802949

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族:
    Alkaline phosphatase family
  • 組織特異性:
    Detected in placenta (at protein level).
  • 數據庫鏈接:

    HGNC: 439

    OMIM: 171800

    KEGG: hsa:250

    STRING: 9606.ENSP00000375881

    UniGene: Hs.284255



主站蜘蛛池模板: yyyy11111少妇影院| 9l国产精品久久久久尤物| 中文精品无码中文字幕无码专区 | 国产探花在线精品一区二区| 超碰国产天天做天天爽| 精品久久久久中文字幕app| 久久天天躁狠狠躁夜夜2020一 | 韩国精品一区二区三区四区 | 亚洲一区二区色情苍井空| 无码人妻黑人中文字幕| 色翁荡熄又大又硬又粗又视频| 插鸡网站在线播放免费观看| 国产av福利久久| 人妻换人妻a片爽麻豆| 成在人线av无码免费| 国产av精品毛片一区二区三区| 国产成人亚洲综合色婷婷秒播| 国产性天天综合网| 欧美性生 活18~19| 手机看片国产av无码| 好紧好爽好深再快点av在线| 人人超人人超碰超国产97超碰 | 久久精品国自产拍| 香蕉av777xxx色综合一区| а√中文在线资源库| 被c到高潮疯狂喷水国产| 99精品国产一区二区三区不卡| 少妇被猛男粗大的猛进出| 中文午夜乱理片无码| 综合 欧美 小说 另类 图| 日本猛少妇色xxxxx猛叫| 亚洲精品成人a在线观看| 狠狠色老熟妇老熟女| 亚洲精品国产一区黑色丝袜| 日本电影一区二区三区| 精品高朝久久久久9999| 久久精品超碰av无码| 真实的国产乱xxxx在线| 国产真实野战在线视频| 亚洲国产精品无码专区影院| 国产精品久久久久久久久久久久午夜片 |