在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. AKIP1 Antibody

AKIP1 Antibody

  • 中文名稱：
    AKIP1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA000979
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of Jurkat cells using BCA3 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    AKIP1
  • 別名：
    AKIP1 antibody; BCA3 antibody; C11orf17A-kinase-interacting protein 1 antibody; Breast cancer-associated gene 3 protein antibody; PKA-interacting protein antibody; Proline-rich protein BCA3 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human BCA3.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade.
  • 基因功能參考文獻(xiàn)：
    1. These results show that AKIP1 is crucial in cervical cancer angiogenesis and growth by elevating the levels of the NF-kappaB-dependent chemokines CXCL1, CXCL2, and CXCL8. PMID: 29520695
    2. Breast carcinoma-associated protein (BCA3) is packaged into Human immunodeficiency virus 1 (HIV-1) particles, and the BCA3 C-terminus is responsible for this incorporation. BCA3 incorporation into HIV-1 particles is mediated by its ability to interact with the catalytic subunit of protein kinase A. There is no effect of incorporated BCA3 on HIV-1 infectivity. PMID: 29677171
    3. The pleiotropic effects of BCA3 in HCC progression. PMID: 29133128
    4. The absence of exon 3 and exon 5 influenced the subcellular localization of BCA3 and nuclear factor kappa B (NF-kB)-dependent gene expression. PMID: 25526186
    5. Data indicate an important role for A-kinase-interacting protein 1 (AKIP1) in esophageal squamous cell carcinoma (ESCC) angiogenesis and lymphangiogenesis. PMID: 24413079
    6. Expression of BCA3 did not affect Mason-Pfizer money virus (MPMV) particle release and proteolytic processing; however, it slightly increased MPMV infectivity. PMID: 24659101
    7. Data indicate A-kinase interacting protein 1 (AKIP1) as a critical molecular regulator and a therapeutic control point for stress adaptation in the heart. PMID: 23319652
    8. action of PKA signaling on the NF-kappaB activation cascade PMID: 20562110
    9. characterization of the BCA3 gene; BCA3 is expressed in breast tumor cells in vivo, and not in surrounding stromal tissue PMID: 12527432
    10. AKIP1 describes a PKA-interacting protein that can contribute to localization by a mechanism that is distinct from A-kinase anchoring proteins that interact with the regulatory subunits. PMID: 15630084
    11. AKIP1 colocalized with p65 within the cells and appeared to retain p65 in nucleus. PMID: 18178962

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Note=Locates to punctate spots.
  • 組織特異性：
    Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 1170

    OMIM: 609191

    KEGG: hsa:56672

    STRING: 9606.ENSP00000310459

    UniGene: Hs.131180



主站蜘蛛池模板： 骚动漫十八禁在线观看| 日本国产网曝视频在线观看| 国产超碰人人爽人人做av| 大伊香蕉精品视频在线直播| 丁香啪啪综合成人亚洲| 日韩精品久久久久久久电影蜜臀| 欧美xxxx做受欧美69| 国产av亚洲aⅴ一区二区| 2019一級特黃色毛片免費看| 在线精品国产成人综合| 人妻丰满熟妇av无码区hd| 少女高清影视在线观看动漫| 午夜毛片不卡高清免费看| 久久国产精品波多野结衣av| 国产精品青青在线观看爽香蕉| 亚洲欧洲自拍拍偷精品网| 狠狠色丁香久久综合婷婷| 亂倫近親相姦中文字幕| 国语做受对白xxxxx在线| 97无码免费人妻超级碰碰碰碰| 国产ww久久久久久久久久| 欧美在线看片a免费观看| 午夜好爽好舒服免费视频| 久热在线播放中文字幕| 免费99精品国产自在在线| 99er国产这里只有精品视频免费| 亚洲国产精品久久久久秋霞小说| 天天做天天爱夜夜爽毛片毛片| 欧美大浪妇猛交饥渴大叫| 波多野结衣爽到高潮大喷| 99精品免视看| 欧美黑人巨大xxxxx| 国产天堂久久天堂av色综合| 黑人又粗又大又硬a片| 成人18禁深夜福利网站app免费 | 久久婷婷五月综合色首页| 少妇高潮太爽了在线观看欧美| 久久婷婷国产综合精品| 亚洲精品无码mⅴ在线观看| 欧美成人天天综合在线| 日韩精品一区二区三区|