在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

AKAP8L Antibody

  • 中文名稱:
    AKAP8L兔多克隆抗體
  • 貨號:
    CSB-PA892152ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA892152ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA892152ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) AKAP8L Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    AKAP8L antibody; NAKAP antibody; NAKAP95 antibody; HRIHFB2018A-kinase anchor protein 8-like antibody; AKAP8-like protein antibody; Helicase A-binding protein 95 antibody; HAP95 antibody; Homologous to AKAP95 protein antibody; HA95 antibody; Neighbor of A-kinase-anchoring protein 95 antibody; Neighbor of AKAP95 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human A-kinase anchor protein 8-like protein (1-240AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Could play a role in constitutive transport element (CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export. Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis. May regulate the initiation phase of DNA replication when associated with TMPO isoform Beta. Required for cell cycle G2/M transition and histone deacetylation during mitosis. In mitotic cells recruits HDAC3 to the vicinity of chromatin leading to deacetylation and subsequent phosphorylation at 'Ser-10' of histone H3; in this function seems to act redundantly with AKAP8. May be involved in regulation of pre-mRNA splicing.; (Microbial infection) In case of EBV infection, may target PRKACA to EBNA-LP-containing nuclear sites to modulate transcription from specific promoters.; (Microbial infection) Can synergize with DHX9 to activate the CTE-mediated gene expression of type D retroviruses.; (Microbial infection) In case of HIV-1 infection, involved in the DHX9-promoted annealing of host tRNA(Lys3) to viral genomic RNA as a primer in reverse transcription; in vitro negatively regulates DHX9 annealing activity.
  • 基因功能參考文獻:
    1. Results indicate that in vitro, the interaction between HA95 and LAP2beta is influenced by a PKA-mediated phosphorylation of HA95 rather than by CDK1- or PKC-mediated phosphorylation of LAP2beta PMID: 12950172
    2. NAKAP-HypA scaffold is a potential nuclear docking site for huntingtin protein and may contribute to the nuclear accumulation of huntingtin observed in HD PMID: 16391387
    3. Nuclear PKA C subunit co-locates with HA95 in splicing factor compartments and regulates pre-mRNA splicing, possibly through a cAMP-independent mechanism. PMID: 17594903
    4. These results infer that RNF43 is a resident protein of the ER and, at least partially, the nuclear membrane, with ubiquitin ligase activity and may be involved in cell growth control potentially through the interaction with HAP95. PMID: 18313049
  • 亞細胞定位:
    Nucleus. Nucleus matrix. Nucleus speckle. Nucleus, PML body. Cytoplasm.
  • 蛋白家族:
    AKAP95 family
  • 組織特異性:
    Ubiquitously expressed. Expressed in the brain cortex (at protein level).
  • 數據庫鏈接:

    HGNC: 29857

    OMIM: 609475

    KEGG: hsa:26993

    STRING: 9606.ENSP00000380557

    UniGene: Hs.399800



主站蜘蛛池模板: 成人免费视频在线观看| 亚洲欧洲自拍拍偷综合| 国产日韩另类综合11页| 国产日韩亚洲大尺度高清| 无码熟熟妇丰满人妻porn| 内射爽无广熟女亚洲| 亚洲一卡二卡三卡四卡| 亚洲人成精品久久久久| 色欲天天婬色婬香综合网完整 | aaa少妇高潮大片免费看| 欧美video性欧美熟妇| 免费播放婬乱男女婬视频国产 | 亚洲欧美v国产一区二区| 亚洲卡一卡二乱码新区仙踪| 亚洲一区二区三区偷拍女厕| 日韩国产成人精品视频| 很黄很色的动态图580期| 女学生14毛片视频片二毛| 久久久久久好爽爽久久| 亚洲欭美日韩颜射在线二| 欧美v亚洲v日韩v最新在线| 老色鬼永久视频网站| 日韩欧美亚洲中文乱码| 精品人妻无码区二区三区| 玩弄中年熟妇正在播放| 图片区小说区激情区偷拍区| 亚洲精品成人网站在线播放| 东京热人妻丝袜av无码| 荫道bbwbbb高潮潮喷| 校园春色~综合网| 亚洲日韩小电影在线观看| 国产欧美国日产高清| 亚洲爆乳精品无码一区二区| 风流老熟女一区二区三区| 白嫩无码人妻丰满熟妇啪啪区百度| 亚洲第一在线综合网站| 免费无码又爽又刺激高潮的视频| 国产做无码视频在线观看| 久久天天躁狠狠躁夜夜av浪潮| 人妻熟女久久久久久久| 波多野结衣一区二区三区av高清|