在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

AFAP1L2 Antibody

  • 中文名稱:
    AFAP1L2兔多克隆抗體
  • 貨號:
    CSB-PA001410GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    AFAP1L2
  • 別名:
    Actin filament-associated protein 1-like 2 antibody; AF1L2_HUMAN antibody; AFAP1-like protein 2 antibody; afap1l2 antibody; CTB-1144G6.4 antibody; KIAA1914 antibody; XB130 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human AFAP1L2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation.
  • 基因功能參考文獻:
    1. present study demonstrated that the expression of XB130 is elevated in CRC cells. Loss of XB130 was associated with decreased invasion and migration of CRC cells, possibly as a result of EMT inhibition. PMID: 28849225
    2. Our results suggest that dissociation between XB130 and Tks5 may facilitate lateral cell migration via XB130/Rac1, and vertical cell migration via Tks5/Cdc42. These molecular mechanisms will help our understanding of airway epithelial repair and regeneration. PMID: 27835612
    3. these observations suggest that XB130 may be a novel molecular marker and potent therapeutic target for prostate PMID: 27509056
    4. Results suggest that Tks5, similar to XB130, plays a role in cell proliferation and cell survival and that the interaction between XB130 and Tks5 appears to be critical for regulation of Src-mediated cellular homeostasis. PMID: 26446840
    5. XB130 is a mediator for nicotine-derived nitrosamine ketone-induced cell migration through its translocation to cell motility related microfilamentous cellular structures. PMID: 25980441
    6. XB130 could be useful as a prognostic marker of recurrence-free and overall survival in invasive ductal breast cancer, as well as for the response to chemotherapy. PMID: 26191231
    7. This is the first study to reveal that XB130 overexpression may be related to the prediction of metastasis potency and poor prognosis for osteosarcoma patients PMID: 26045762
    8. Results showed significant interaction between variants at TERF1 and AFAP1L2 loci. Given the key role of TERF1 in telomere biology and its physical interaction with AFAP1L2, these results support a role for telomere dysfunction in melanoma development. PMID: 25892537
    9. High XB130 expression is associated with pancreatic ductal adenocarcinoma. PMID: 24581082
    10. XB130 enhances cell motility and invasiveness by modulating the epithelial-mesenchymal transition-like process. PMID: 24387290
    11. High nuclear expression of XB130 is associated with esophageal squamous cell carcinoma. PMID: 22805860
    12. XB130 could promote growth of cancer cells by regulating expression of tumor suppressive miRNAs and their targeted genes. PMID: 23527086
    13. XB130 is a substrate of multiple protein tyrosine kinases, and it can regulate cell proliferation and survival through modulating selected down-stream signals of PI3K/Akt pathway PMID: 22928011
    14. reduced XB130 protein expression is a prognostic biomarker for shorter survival and a higher recurrence rate in patients with gastric cancer PMID: 22927913
    15. Protein expression of XB130 is not associated with the postoperative prognosis of patients with hepatocellular carcinoma. PMID: 22190283
    16. These observations suggest that the expression of XB130 in these cancer cells may affect cell proliferation and survival by controlling the expression of multiple genes, especially transcription regulators. PMID: 21224076

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 組織特異性:
    Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas.
  • 數據庫鏈接:

    HGNC: 25901

    OMIM: 612420

    KEGG: hsa:84632

    STRING: 9606.ENSP00000303042

    UniGene: Hs.501106



主站蜘蛛池模板: 欧洲熟妇色xxxxx欧美老妇伦| 国产精品久久欧美久久一区| 情人伊人久久综合亚洲| 日韩人妻无码一区二区三区久久99| 人妻少妇精品视频无码专区| 久久亚洲日韩精品一区二区三区| 97人妻天天摸天天爽天天| 中文综合在线观| 国产模特嫩模私拍视频在线| 成人网站www污污污网站| 欧美另类videossexo高潮| 欧美人与物videos另类xxxxx| 青青草国产线观看| 英语老师丝袜娇喘好爽视频| 亚洲a∨无码无在线观看| 玩弄人妻少妇500系列网址| 亚洲成av人在线观看天堂无码| 浓毛欧美老妇乱子伦视频| 久久精品一区二区三区四区| 国产精品原创巨作av女教师 | 亚洲精品国产嫩草在线观看东京热| 人人妻碰人人免费| 国产精品夜色一区二区三区| 极品少妇被后入内射视| 国产亚洲福利在线视频| 国产精品线路一线路二| 四川丰满妇女毛片四川话| 狠狠色噜噜狠狠色综合久| 中文字幕 欧美精品 第1页| 东北老女人高潮大叫对白| 亚洲精品久久久蜜桃| 日韩内射激情视频在线播放免费 | 国产探花在线精品一区二区| 亚洲一区在线日韩在线尤物| 免费拍拍拍网站| 久久综合久久鬼色| 国内精品乱码卡一卡2卡三卡新区 亚洲爆乳成av人在线视菜奈实 | 国产精品 自在自线| 亚洲精品无码鲁网午夜| 久久国产成人午夜av影院| 久久精品国产亚洲夜色av网站|