ADCY9 Antibody
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中文名稱：ADCY9兔多克隆抗體
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貨號(hào)：CSB-PA006850
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規(guī)格：￥1090
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圖片：
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Western Blot analysis of HuvEc cells using A Cyclase IX Polyclonal Antibody
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：ADCY 9 antibody; ADCY9 antibody; ADCY9_HUMAN antibody; Adenylate cyclase 9 antibody; Adenylate cyclase type 9 antibody; Adenylate cyclase type IX antibody; Adenylyl cyclase 9 antibody; ATP pyrophosphate lyase 9 antibody; ATP pyrophosphate-lyase 9 antibody; KIAA0520 antibody; Type IX adenylyl cyclase antibody; Type IX ATP pyrophosphate lyase antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Synthesized peptide derived from the N-terminal region of Human A Cyclase IX.
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：WB, IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:10000 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein-coupled receptors. Contributes to signaling cascades activated by CRH (corticotropin-releasing factor), corticosteroids and beta-adrenergic receptors.
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基因功能參考文獻(xiàn)：
- ADCY9 immunoreactivity score was significantly higher (P=0.002) in tumor tissues (6.40+/-1.26, n=200) than in adjacent normal samples (4.13+/-0.83, n=8). The IRS and mRNA expression of ADCY9 were correlated to colon cancer TNM staging. PMID: 29292367
- polymorphisms in the ADCY9 gene are significantly associated with asthma and/or allergy markers PMID: 28076799
- The effects of dalcetrapib on atherosclerotic outcomes are determined by correlated polymorphisms in the ADCY9 gene. PMID: 25583994
- The importance of miR-181a-mediated AC9 downregulation in acute promyelocytic leukemia, is reported. PMID: 24722286
- Data indicate that adenylyl cyclase 9 (AC9) transcript is a direct target of miR-181b. PMID: 24269684
- in heart, Yotiao brings together PKA, PP1, PDE4D3, AC9, and the I(Ks) channel to achieve localized temporal regulation of beta-adrenergic stimulation. PMID: 22778270
- The HIV-1 regulatory protein Tat was shown to inhibit the activity of adenylyl cyclase in rat microglial cells. PMID: 11299302
- A case-control study using Ile772Met and a repeat (TTTA)n showed no significant association with mood disorders in Japan. PMID: 11840511
- associated with bipolar disorder using pedigree linkage disequilibrium PMID: 12082561
- blocking glycosylation of AC9 significantly attenuates Galpha(s) stimulation. PMID: 14996950
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亞細(xì)胞定位：Cell membrane; Multi-pass membrane protein.
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蛋白家族：Adenylyl cyclase class-4/guanylyl cyclase family
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組織特異性：Detected in skeletal muscle, pancreas, lung, heart, kidney, liver, brain and placenta. Expressed in multiple cells of the lung, with expression highest in airway smooth muscle.
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數(shù)據(jù)庫鏈接：
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