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  4. ADAP2 Antibody

ADAP2 Antibody

  • 中文名稱：
    ADAP2兔多克隆抗體
  • 貨號：
    CSB-PA889071LA01HU
  • 規格：
    ￥440
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ADAP2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ADAP2
  • 別名：
    Adap2 antibody; ADAP2_HUMAN antibody; Arf-GAP with dual PH domain-containing protein 2 antibody; ArfGAP with dual PH domains 2 antibody; cent b antibody; Centa 2 antibody; CENTA2 antibody; Centaurin alpha 2 antibody; Centaurin alpha 2 protein antibody; Centaurin beta antibody; Centaurin-alpha-2 antibody; Cnt-a2 antibody; HSA272195 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Arf-GAP with dual PH domain-containing protein 2 protein (110-381AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，ADAP2 Antibody (CSB-PA889071LA01HU)，的標記方式是Non-conjugated。對于ADAP2 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA889071LB01HU ADAP2 Antibody, HRP conjugated ELISA
    FITC CSB-PA889071LC01HU ADAP2 Antibody, FITC conjugated
    Biotin CSB-PA889071LD01HU ADAP2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    GTPase-activating protein for the ADP ribosylation factor family (Potential). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). Possesses a stoichiometry of two binding sites for InsP4 with identical affinity.
  • 基因功能參考文獻：
    1. ArfGAP domain-containing protein 2 (ADAP2) is identified as a key novel scaffolding protein that integrates different modules of the RIG-I pathway, located at distinct subcellular locations, and mediates cellular antiviral type I interferon production. PMID: 27956705
    2. Data suggest ADAP2 (an interferon-beta stimulated gene) disrupts pathogenic internalization of some RNA viruses/virions (dengue, vesicular stomatitis) by altering ADP ribosylation factor 6-mediated processes including up-regulation of pinocytosis. PMID: 26372645
    3. Centaurin-alpha interacts with beta-tubulin and stabilizes microtubules. PMID: 23285209
    4. The human gene for centaurin alpha 2 is located on chromosome 17, position 17q11.2, near the neurofibromatosis 1 (NF1) locus and concentrated at the plasma membrane. PMID: 14690521
  • 亞細胞定位：
    Cytoplasm. Cell membrane. Note=Constitutively associated with the plasma membrane. Excluded from the nucleus.
  • 組織特異性：
    Highly expressed in placenta, spleen, kidney, skeletal muscle and adrenal gland. Weakly expressed in thyroid, liver, heart, lung, small intestine, peripheral blood leukocytes. Not detected in spinal cord, brain, stomach, trachea, colon, lymph node and bon
  • 數據庫鏈接：

    HGNC: 16487

    OMIM: 608635

    KEGG: hsa:55803

    STRING: 9606.ENSP00000329468

    UniGene: Hs.514063



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