ADAMTS15 Antibody
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中文名稱：ADAMTS15兔多克隆抗體
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貨號：CSB-PA139279
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規格：￥1100
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圖片：
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: CSB-PA139279(ADAMTS15 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 minutes
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其他：
產品詳情
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Uniprot No.：
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基因名：ADAMTS15
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別名：A disintegrin and metalloproteinase with thrombospondin motifs 15 antibody; A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 motif 15 antibody; A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 motif 15 preproprotein antibody; A disintegrin like and metalloprotease with thrombospondin type 1 motif 15 antibody; A disintegrin like and metalloprotease with thrombospondin type 1 motif 15 preproprotein antibody; ADAM metallopeptidase with thrombospondin type 1 motif 15 antibody; ADAM TS 15 antibody; ADAM TS15 antibody; ADAM-TS 15 antibody; ADAM-TS15 antibody; ADAMTS 15 antibody; ADAMTS-15 antibody; ADAMTS15 antibody; ATS15_HUMAN antibody; MGC126403 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthetic peptide of Human ADAMTS15
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 WB 1:200-1:1000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Metalloprotease which has proteolytic activity against the proteoglycan VCAN, cleaving it at the 'Glu-1428-|-1429-Ala' site. Cleaves VCAN in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration.
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基因功能參考文獻：
- ADAMTS4 and ADAMTS15 were upregulated in symptomatic uterine leiomyomas. PMID: 28323982
- ADAMTS15 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
- ADAMTS15 is a candidate gene for intracranial aneurysms PMID: 25649796
- ADAMTS-15 has multiple actions on tumor pathophysiology including modulation of cell-extracellular matrix interactions, which likely involve syndecan-4. PMID: 25099234
- Versican processing by ADAMTS5 and ADAMTS15 contribute to muscle fiber formation. PMID: 23233679
- ADAMTS-15 but not ADAMTS-1 expression was downregulated by androgen in LNCaP prostate cancer cells, possibly through androgen response elements associated with the gene PMID: 20590445
- ADAMTS8 and ADAMTS15 have emerged as novel predictors of survival in patients with breast carcinoma PMID: 16152618
- ADAMTS15 may be target of inactivating mutations in human cancer. PMID: 19458070
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亞細胞定位：Secreted, extracellular space, extracellular matrix. Cell surface.
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組織特異性：Expressed in fetal liver and kidney, but not in any of the adult tissues examined.
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數據庫鏈接：
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