在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ACSL6 Antibody

ACSL6 Antibody

  • 中文名稱：
    ACSL6兔多克隆抗體
  • 貨號：
    CSB-PA892139ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: ACSL6 antibody at 4.64µg/ml
      Lane 1: Mouse liver tissue
      Lane 2: Mouse heart tissue
      Lane 3: Mouse brain tissue
      Lane 4: Mouse gonadal tissue
      Lane 5: Jurkat whole cell lysate
      Lane 6: Raji whole cell lysate
      Lane 7: K562 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 78, 81, 75, 77, 80, 70 kDa
      Observed band size: 78 kDa
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA892139ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA892139ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ACSL6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    ACSL6 antibody; ACS2 antibody; FACL6 antibody; KIAA0837 antibody; LACS5Long-chain-fatty-acid--CoA ligase 6 antibody; EC 6.2.1.3 antibody; Arachidonate--CoA ligase antibody; EC 6.2.1.15 antibody; Long-chain acyl-CoA synthetase 6 antibody; LACS 6 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Long-chain-fatty-acid--CoA ligase 6 protein (458-697AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
  • 基因功能參考文獻：
    1. ACSL6 drives acyl-CoA toward lipid synthesis and its downregulation improves mitochondrial biogenesis, respiratory capacity and lipid oxidation PMID: 27647415
    2. variations in the ACSL6 gene may contribute to the quantity of cigarettes smoked PMID: 22205969
    3. The alternative fatty acid Gate-domain motifs are essential determinants for the activity of the human ACSL6 isoforms, which appear to act as homodimeric enzyme as well as in complex with other spliced forms. PMID: 20429931
    4. The t(5;12)(q23-31;p13)translocation with ETV6-ACSL6 genomic alteration rearrangement in polycythemia vera patients was reported. PMID: 16572202
    5. Analyses did not yield convincing evidence for associations of schizophrenia with ACSL6 PMID: 16827919
    6. Three ACSL6 spliced variants of a mutually exclusive exon pair are reported, they encode a slightly different short motif which contains a conserved structural domain, the fatty acid Gate domain. PMID: 16834775
    7. haplotypes underlying the SPEC2/PDZ-GEF2/ACSL6 region are associated with schizophrenia PMID: 17030554
    8. The acyl-coenzyme A synthetase long-chain family member 6 (ACSL6) gene on chromosome 5q31 was associated with premature ovarian failure and identified disease-susceptibility haplotypes. PMID: 18555221
    9. ACSL6 is highly associated with schizophrenia and several haplotypes in this haploblock have about twofold to 10-fold increase in the affected subjects in Han Chinese. PMID: 18718982

    顯示更多

    收起更多

  • 相關疾病：
    A chromosomal aberration involving ACSL6 may be a cause of myelodysplastic syndrome with basophilia. Translocation t(5;12)(q31;p13) with ETV6.
  • 亞細胞定位：
    Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein.
  • 蛋白家族：
    ATP-dependent AMP-binding enzyme family
  • 組織特異性：
    Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain.
  • 數據庫鏈接：

    HGNC: 16496

    OMIM: 604443

    KEGG: hsa:23305

    STRING: 9606.ENSP00000296869

    UniGene: Hs.14945



主站蜘蛛池模板： 亚洲性夜夜综合久久7777| 亚洲精品国产精品国自产观看| 欧美日韩免费做爰大片人| 亚洲性视频免费视频网站| 亚洲天堂在线观看完整版| 国产欧美va天堂在线观看视频| 无码av无码天堂资源网| 欧美xxxx做受欧美1314| 久热中文字幕无码视频| 韩国v欧美v亚洲v日本v| 亚洲一区二区三区高清av| 国内精品久久久久影视老司机| 亚洲熟妇无码八v在线播放| 国产无套精品一区二区| 精品 日韩 国产 欧美 视频| 色综合久久久久综合99| 亚洲图片小说激情综合| 日日碰狠狠躁久久躁婷婷| 一本大道久久东京热无码av| 亚洲一区二区三区波多野结衣| 人妻熟女一区二区aⅴ清水理纱 | 国产欧美高清在线观看| 中文字幕一区二区三区精华液 | 久久人人爽av亚洲精品天堂| 高清国产亚洲精品自在久久| 久久ee热这里只有精品| 午夜福利伦伦电影理论片在线观看| 男阳茎进女阳道视频大全| 免费无码av片在线观看国产| 国产精品夜夜春夜夜爽久久小说| 性生交大片免费看女人按摩| 国产日产欧产精品精品| 99久e在线精品视频在线| 日韩内射美女人妻一区二区三区| 午夜精品久久久久久久爽| 国内精品久久久久影院免费| 7777久久久国产精品消防器材| 国产又黄又爽又猛免费视频播放| 国产在线观看超清无码视频一区二区| 亚洲人成色77777在线观看大战| 国产成人精品一区二区三区视频|