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Your Good Partner in Biology Research

ACR Antibody

  • 中文名稱:
    ACR兔多克隆抗體
  • 貨號:
    CSB-PA000002
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of HepG2 cells using Acrosin Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ACR
  • 別名:
    Acr antibody; ACRO_HUMAN antibody; Acrosin heavy chain antibody; Acrosin precursor antibody; ACRS antibody; Preproacrosin antibody; Proacrosin antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the N-terminal region of Human Acrosin.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.
  • 基因功能參考文獻:
    1. Data indicate that the positive expression of studied genes fertilization rate for GAPDHS positive subset was 66%, ACR - 71%, SPATA22 - 68%, MND1 - 70%, pregnancy rates were 8%, 6%, 18% and 36% respectively. PMID: 23675907
    2. Sperm DNA damage is closely related with sperm-nucleoprotein transition, acrosin activity and seminal parameters. PMID: 23297503
    3. DNA immunization against proacrosin impairs fertility in male mice. PMID: 22452365
    4. Binding sites for recombinant human zona pellucida (ZP) glycoproteins located at the N- and C-termini of proacrosin reveal a key role of the proenzyme in the interaction. PMID: 15950651
  • 蛋白家族:
    Peptidase S1 family
  • 數據庫鏈接:

    HGNC: 126

    OMIM: 102480

    KEGG: hsa:49

    STRING: 9606.ENSP00000216139

    UniGene: Hs.370870



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