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  4. ACOX2 Antibody

ACOX2 Antibody

  • 中文名稱：
    ACOX2兔多克隆抗體
  • 貨號：
    CSB-PA246246
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA246246(ACOX2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA246246(ACOX2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse liver tissue, Mouse kidney tissue, Primary antibody: CSB-PA246246(ACOX2 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase antibody; 12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase antibody; 3 alpha 7 alpha 12 alpha trihydroxy 5 beta cholestanoyl CoA oxidase antibody; 3 alpha 7 alpha12 alpha trihydroxy 5 beta cholestanoyl CoA 24 hydroxylase antibody; 3-alpha antibody; 7-alpha antibody; ACOX 2 antibody; ACOX2 antibody; ACOX2_HUMAN antibody; Acyl CoA oxidase 2 antibody; Acyl Coenzyme A oxidase 2 antibody; Acyl Coenzyme A oxidase 2 branched chain antibody; Acyl coenzyme A oxidase 2 peroxisomal antibody; BCOX antibody; BRCACOX antibody; BRCOX antibody; Peroxisomal acyl-coenzyme A oxidase 2 antibody; Peroxisomal branched chain acyl CoA oxidase antibody; THCA CoA oxidase antibody; THCA-CoA oxidase antibody; THCCox antibody; Trihydroxycoprostanoyl CoA oxidase antibody; Trihydroxycoprostanoyl-CoA oxidase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human ACOX2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids. Capable of oxidizing short as well as long chain 2-methyl branched fatty acids.
  • 基因功能參考文獻：
    1. We have identified by the first time in a young patient and his only sister a familiar genetic defect of an enzyme called ACOX2, which participates in the transformation of cholesterol into bile acids as a cause of increased serum transaminases in the absence of any other symptomatology. PMID: 27884763
    2. Results found an ACOX2 variant present in a subset of human breast cancers and associated with improved outcome ER+ tumors suggesting it as a potential novel therapeutic biomarker in ER+ breast tumors. PMID: 26183823
    3. Our results suggest that downregulation of ACOX2 is a shared risk factor for PE and CVD. PMID: 21343950
  • 相關疾病：
    Congenital bile acid synthesis defect 6 (CBAS6)
  • 亞細胞定位：
    Peroxisome.
  • 蛋白家族：
    Acyl-CoA oxidase family
  • 組織特異性：
    Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney.
  • 數據庫鏈接：

    HGNC: 120

    OMIM: 601641

    KEGG: hsa:8309

    STRING: 9606.ENSP00000307697

    UniGene: Hs.444959



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