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ACOT12 Antibody

  • 中文名稱:
    ACOT12兔多克隆抗體
  • 貨號:
    CSB-PA066461
  • 規格:
    ¥2024
  • 圖片:
    • Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using ACOT12 antibody.
    • Immunofluorescence analysis of A549 cells, using ACOT12 antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ACOT12 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ACOT12
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from internal of Human ACOT12.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC,IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:50-1:100
    IF 1:100-1:500
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Preferentially hydrolyzes acetyl-CoA.
  • 基因功能參考文獻:
    1. using a range of structural and biophysical techniques, it is demonstrated that ACOT12 is a trimer rather than a tetramer and that neither ADP nor ATP exert their regulatory effects by altering the oligomeric status of the enzyme PMID: 25002576
    2. The human CACH cDNA encodes a 555-amino-acid sequence that is 81.4%/78.7% identical to those of the mouse/rat homologue, suggesting a conserved role for this enzyme in the human and rodent livers. PMID: 16951743
  • 亞細胞定位:
    Cytoplasm, cytosol.
  • 數據庫鏈接:

    HGNC: 24436

    OMIM: 614315

    KEGG: hsa:134526

    STRING: 9606.ENSP00000303246

    UniGene: Hs.591756



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