在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ACADS Antibody

ACADS Antibody

  • 中文名稱：
    ACADS兔多克隆抗體
  • 貨號：
    CSB-PA957686
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA957686(ACADS Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA957686(ACADS Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human liver cancer tissue, rat kidney tissue, human fetal liver tissue, Primary antibody: CSB-PA957686(ACADS Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 90 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    ACADS
  • 別名：
    ACAD3 antibody; ACADS antibody; ACADS_HUMAN antibody; Acyl Coenzyme A dehydrogenase; C2 to C3 short chain antibody; Acyl-CoA dehydrogenase; C2 to C3 short chain antibody; Acyl-CoA dehydrogenase; short chain antibody; Acyl-Coenzyme A dehydrogenase; short chain antibody; AI196007 antibody; Bcd-1 antibody; Bcd1 antibody; Butyryl CoA dehydrogenase antibody; Butyryl-CoA dehydrogenase antibody; EC 1.3.99.2 antibody; mitochondrial antibody; SCAD antibody; Short chain acyl CoA dehydrogenase antibody; Short-chain specific acyl-CoA dehydrogenase antibody; Short-chain specific acyl-CoA dehydrogenase; mitochondrial antibody; Unsaturated acyl CoA reductase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human ACADS
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, short-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 4 to 6 carbons long primary chains.
  • 基因功能參考文獻：
    1. a link between ACADS susceptibility variants and abnormal beta-oxidation consistent with known altered kinetics of these variants PMID: 28532786
    2. Korean patients with Short-chain acyl-CoA dehydrogenase deficiency showed heterogenous clinical features and ACADS genotype. PMID: 27466294
    3. Thirteen proteins had significant alteration in protein levels in patients carrying variation c.319C>T in ACADS compared to controls and they belonged to various pathways, such as the antioxidant system and amino acid metabolism. PMID: 24485985
    4. Results show significant upregulation of LASP1 and SCAD protein levels in acute psychotic bipolar disorder samples. PMID: 24554194
    5. IVD mutations in Asian populations are distinct from these in Western populations. PMID: 22004070
    6. physiological concentrations of flavin adenine dinucleotide resulted in a spectacular enhancement of the thermal stabilities of SCAD and prevented enzymatic activity loss PMID: 21968293
    7. In glucose-tolerant individuals the minor C-allele of rs2014355 of ACADS was associated with reduced measures of glucose-stimulated insulin release during an oral glucose tolerance test. PMID: 21211036
    8. We therefore propose that SCAD misfolding leads to production of ROS, which in turn leads to fission and a grain-like structure of the mitochondrial reticulum. This finding indicates a toxic response elicited by misfolded p.Arg83Cys SCAD proteins PMID: 20371198
    9. Molecular pathogenesis of a novel mutation, G108D, in ACADS identified in subjects with ACADS deficiency. PMID: 20376488
    10. Reduction of catalytic activity and stability in polymorphic variant of SCAD (Gly185Ser) is caused by decreased flexibility in the tertiary conformation of the mutant enzyme. PMID: 12220177
    11. Replacement of the catalytic glutamate in either short-chain acyl-CoA dehydrogenase (SCAD) or isovaleryl-CoA dehydrogenase (IVD)with glycine resulted in a several-fold reduction in affinity for substrate. PMID: 16376132
    12. One of 220 SIDs cases was homozygous for the prevalent MCAD A985G mutation. PMID: 18045290
    13. The c.319C>T mutation can lead to wide clinical and biochemical phenotypic variability, suggesting a complex multifactorial/polygenic condition. This should be screened for in individuals with multicore myopathy, particularly among the Ashkenazim. PMID: 18054510
    14. A homozygous variant allele of the SCAD gene, 625G>A, was detected in new case of short-chain acyl-CoA dehydrogenase deficiency. PMID: 18175080
    15. Extensive laboratory investigations indicate that the short-chain acyl-CoA dehydrogenase gene variant is likely preventing or delaying the normal expression of the Prader-Willi syndrome phenotype. PMID: 18184946
    16. SCAD deficiency should be considered as a disorder of protein folding that can lead to clinical disease in combination with other genetic and environmental factors. PMID: 18523805
    17. A deoxyribonucleic analysis revealed the presence of a 625G>A (G-to-A substitution at nucleotide 625) variant short-chain acyl-coenzyme A dehydrogenase gene polymorphism. PMID: 18539996
    18. SCAD deficiency cause a disorder that leads to the accumulation of butyrylcarnitine and ethylmalonic acid in blood and urine. PMID: 18977676

    顯示更多

    收起更多

  • 相關疾病：
    Acyl-CoA dehydrogenase short-chain deficiency (ACADSD)
  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Acyl-CoA dehydrogenase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 90

    OMIM: 201470

    KEGG: hsa:35

    STRING: 9606.ENSP00000242592

    UniGene: Hs.507076



主站蜘蛛池模板： 欧美一区二区三区视频在线观看| 少妇无码av无码专区| 国产一区二区三区免费观看在线 | 欧美精品高清在线观看| av无码一区二区大桥久未| 曰批免费视频播放免费直播| 精品无码乱码av| 国产成人a∨激情视频厨房| 对白脏话肉麻粗话av| 久久精品日日躁夜夜躁欧美| 免费乱理伦片在线观看八戒| 亚洲欧洲国产码专区在线观看 | 奇米综合四色77777久久| 中文字幕人妻第一区| 国产又大又硬又粗| 精品国产一区二区三区四区五区| 国产在线视频天天综合网| 国产精品卡一卡2卡三卡网站| 精品久久久久香蕉网| 欧美精品videosex性欧美| 久久综合一色综合久久小蛇 | 国产aⅴ精品一区二区三区| 亚洲电影在线观看| 99久久久无码国产精品古装| 国产精品美女久久久浪潮av| 国产女女做受ⅹxx高潮| 性色av免费观看| 最新69国产成人精品视频免费| 婷婷综合缴情亚洲狠狠| 夜夜躁狠狠躁日日躁视频| 中国少妇无码专区| 人妻人人澡人人添人人爽人人玩| 激情av无码后入| 国产av国片精品| 国产日韩欧美亚洲精品中字| 18禁止午夜福利体验区| 少妇人妻av无码专区| 亚洲精品一区二区三区在线观看 | 伊人久久大香线蕉av波多野结衣| 免费无码黄十八禁网站在线观看 | 双腿张开被9个男人调教|