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  4. ABI3 Antibody, HRP conjugated

ABI3 Antibody, HRP conjugated

  • 中文名稱：
    ABI3兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA873732LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ABI3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ABI3
  • 別名：
    ABI3 antibody; NESHABI gene family member 3 antibody; New molecule including SH3 antibody; Nesh antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human ABI gene family member 3 protein (1-366AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May inhibit tumor metastasis. In vitro, reduces cell motility.
  • 基因功能參考文獻：
    1. Low ABI3 expression is associated with thyroid carcinomas. PMID: 27036019
    2. Data show that protein-altering changes are in PLCG2, ABI3, and TREM2 genes highly expressed in microglia and highlight an immune-related protein-protein interaction network in Alzheimer's disease. PMID: 28714976
    3. Result links ABI3 to the pathogenesis and progression of some cancers and suggests that ABI3 or its pathway might have interest as therapeutic target. PMID: 21223585
    4. Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells. PMID: 11956071
  • 亞細胞定位：
    Cytoplasm. Note=Colocalizes with PAK2 at leading edge of cells.
  • 蛋白家族：
    ABI family
  • 組織特異性：
    Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle.
  • 數據庫鏈接：

    HGNC: 29859

    OMIM: 606363

    KEGG: hsa:51225

    STRING: 9606.ENSP00000225941

    UniGene: Hs.130719



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