在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ABI2 Antibody

  • 中文名稱:
    ABI2兔多克隆抗體
  • 貨號:
    CSB-PA001102GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Abelson interactor 2 antibody; ABI 2 antibody; Abi-2 antibody; ABI2 antibody; ABI2_HUMAN antibody; ABI2B antibody; Abl binding protein 3 antibody; Abl interacting protein 1 (SH3 containing protein) antibody; Abl interactor 2 antibody; Abl interactor protein 2b antibody; Abl-binding protein 3 antibody; AblBP3 antibody; AIP 1 antibody; Arg binding protein 1 antibody; Arg protein tyrosine kinase binding protein antibody; Arg-binding protein 1 antibody; ArgBP1 antibody; ARGBPIA antibody; ArgBPIB antibody; OTTHUMP00000163783 antibody; OTTHUMP00000163784 antibody; OTTHUMP00000206182 antibody; OTTHUMP00000206183 antibody; OTTHUMP00000206184 antibody; OTTHUMP00000206185 antibody; SSH3BP2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ABI2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation. Acts as regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge. Contributes to the regulation of actin assembly at the tips of neuron projections. In particular, controls dendritic spine morphogenesis and may promote dendritic spine specification toward large mushroom-type spines known as repositories of memory in the brain. In hippocampal neurons, may mediate actin-dependent BDNF-NTRK2 early endocytic trafficking that triggers dendrite outgrowth. Participates in ocular lens morphogenesis, likely by regulating lamellipodia-driven adherens junction formation at the epithelial cell-secondary lens fiber interface. Also required for nascent adherens junction assembly in epithelial cells.
  • 基因功能參考文獻:
    1. TIS21 attenuated Doxorubicin-induced cancer cell senescence by inhibiting linear actin nucleation via Nox4-ROS-ABI2-DRF signal cascade PMID: 27932314
    2. Abl-interactor 2 (ABI2) is a novel MLL translocation partner in acute myeloid leukemia. PMID: 22304832
    3. Abi-2 may have a key regulatory function in leiomyomas cellular/tissue structural organization during growth and regression PMID: 16488906
    4. disruption of the interaction between Bcr-Abl and Abi1 by mutations either in Bcr-Abl or Abi1 not only abolished tyrosine phosphorylation of Abi1 and membrane translocation of Abi1/WAVE2 PMID: 17389688
    5. TRIM32 is a novel oncogene that promotes tumor growth, metastasis, and resistance to anticancer drugs via degradation of Abl-interactor 2 PMID: 18632609

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.; [Isoform 1]: Cell projection, lamellipodium. Cell projection, filopodium. Cytoplasm, cytoskeleton. Cell junction, adherens junction.
  • 蛋白家族:
    ABI family
  • 組織特異性:
    Widely expressed. Abundant in testes, ovary, thymus, and colon, with lower but detectable levels in prostate, peripheral blood leukocytes, and spleen.
  • 數據庫鏈接:

    HGNC: 24011

    OMIM: 606442

    KEGG: hsa:10152

    UniGene: Hs.471156



主站蜘蛛池模板: 久久久国产99久久国产久麻豆| 久久精品99久久香蕉国产色戒 | 午夜天堂av天堂久久久| 国产精品美女一区二区视频| 超碰aⅴ人人做人人爽| 一色屋精品视频在线观看免费 | 午夜无码成人免费视频| 国产成人精品日本亚洲专区61| 国产精品爆乳在线播放第一人称 | 中文字幕+乱码+中文字幕一区| 久久久久亚洲精品| 性xxxx搡xxxxx搡欧美| 欧美尺码专线欧洲b1b1| 亚洲成av人片在线观看橙子| 露脸叫床粗话东北少妇| 呦系列视频一区二区三区| 亚洲高清乱码午夜电影网| 又黄又湿啪啪响18禁| 婷婷射精av这里只有精品| 久久99精品国产麻豆| 中文字幕人妻熟女av| 中文字幕大看蕉在线观看| 无码人妻aⅴ一区二区三区69岛 | 忘忧草社区中文字幕www| 国产免费午夜福利不卡片在线| 免费无码又爽又刺激聊天app| 白又丰满大屁股bbbbb| 97人洗澡人人澡人人爽人人模| 久久九九精品国产免费看小说| 亚洲国产精品一区二区成人片| 一二三四在线观看免费视频| 色 成人 亚洲| 国产吃奶在线观看| 日韩经典午夜福利发布| 无码国模国产在线观看免费 | 一边摸一边做爽的免费视频日本 | 欧美99久久无码一区人妻a片| 亚洲国产欧美日韩在线人成| 小说区 图片区色 综合区| 久爱无码精品免费视频在线观看| 本道久久综合无码中文字幕|