在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ABHD6 Antibody

ABHD6 Antibody

  • 中文名稱：
    ABHD6兔多克隆抗體
  • 貨號：
    CSB-PA000792
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of COLO205 cells using ABHD6 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    ABHD6Monoacylglycerol lipase ABHD6 antibody; EC 3.1.1.23 antibody; 2-arachidonoylglycerol hydrolase antibody; Abhydrolase domain-containing protein 6 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ABHD6.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids. Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting.
  • 基因功能參考文獻：
    1. Data suggest that ABHD6 plays important role in regulation of signaling via monoacylglycerols (MAGs) in both central and peripheral tissues; alterations in MAG signaling are involved in type 2 diabetes, obesity, and metabolic syndrome. [REVIEW] PMID: 28880480
    2. The hydrolase activity of ABHD6 was not required for the effects of ABHD6 on AMPAR function in either neurons or transfected HEK293T cells. Thus, these findings reveal a novel and unexpected mechanism governing AMPAR trafficking at synapses through ABHD6. PMID: 27114538
    3. data suggest that ABHD6 controls BMP catabolism and is therefore part of the late endosomal/lysosomal lipid-sorting machinery PMID: 26491015
    4. ABHD6 increases from neonatal age. PMID: 22827915
    5. Data show that the three hydrolases are genuine MAG lipases; medium-chain saturated MAGs were the best substrates for hABHD6 and hMAGL, whereas hABHD12 preferred the 1 (3)- and 2-isomers of arachidonoylglycerol. PMID: 22969151
    6. High expression of ABHD6 in Ewing family tumors (EFT) in comparison to normal tissues and other tumors suggests that ABHD6 might be an interesting new diagnostic or therapeutic target for EFT. PMID: 19793082
    7. report the tissue distribution, subcellular location and differential distribution among cancer cell lines of Abhd6, one unannotated member of this group PMID: 18360779

    顯示更多

    收起更多

  • 亞細胞定位：
    Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein. Mitochondrion membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    AB hydrolase superfamily
  • 數據庫鏈接：

    HGNC: 21398

    KEGG: hsa:57406

    STRING: 9606.ENSP00000295962

    UniGene: Hs.476454



主站蜘蛛池模板： 国产精品186在线观看在线播放| 久久无码av一区二区三区电影网| 亚洲色大成网站www永久男同| 日韩av高清在线观看| 欧美极p品少妇的xxxxx| 免费播放婬乱男女婬视频国产| 麻豆果冻传媒2021精品传媒一区| 国产色视频一区二区三区| 小雪好紧好滑好湿好爽视频| 999久久久精品国产消防器材| 好吊妞人成视频在线观看27du| 99精品偷自拍| 国产极品美女到高潮无套| 日本丰满老妇bbw| 久久久久久久久久久久久9999| 亚洲h在线播放在线观看h| 国产 高清 无码 在线播放| 国产亚洲精品久久一区二区 | 亚洲午夜成人片| 欧美成人一区二区三区| 精品视频国产狼友视频| 亚洲精品嫩草研究院久久| 精品久久久久久久久久久aⅴ| 久久人妻无码中文字幕第一| 乱色国内精品视频在线| 扒开双腿疯狂进出爽爽爽视频| 国产 在线 | 日韩| 日韩内射激情视频在线播放免费| 国产女人乱子对白av片 | 中字乱码视频| 久久天天躁狠狠躁夜夜躁2014| 少妇的丰满3中文字幕| 亚洲一区在线日韩在线尤物| 亚洲人成网亚洲欧洲无码| 欧洲熟妇性色黄| 西西人体大胆啪啪实拍| 国产精品18禁污污网站| 人妻少妇精品中文字幕av| 亚洲电影天堂av2017| 国内精品免费网站牛牛| 69精品丰满人妻无码视频a片|