在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ABHD2 Antibody, HRP conjugated

ABHD2 Antibody, HRP conjugated

  • 中文名稱：
    ABHD2兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA001094LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ABHD2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ABHD2
  • 別名：
    ABHD2; LABH2; Monoacylglycerol lipase ABHD2; 2-arachidonoylglycerol hydrolase; Abhydrolase domain-containing protein 2; Acetylesterase; Lung alpha/beta hydrolase 2; Progesterone-sensitive lipase; Protein PHPS1-2
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Monoacylglycerol lipase ABHD2 protein (31-320AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation. May also play a role in smooth muscle cells migration.
  • 基因功能參考文獻：
    1. Suppression of ABHD2 in OVCA420 cells increased phosphorylated p38 and ERK, platinum resistance, and side population cells (p<0.01, respectively). Conversely, overexpression of ABHD2 decreased resistance to anoikis (p<0.05) and the amount of phosphorylated p38 and ERK in OVCA420 and SKOV3 cells. PMID: 27323405
    2. A mutant ABHD2 developed with alanine in place of Ser(207). PMID: 27247428
    3. These results show that joint tests of main effects and gene-gene interaction reveal associations at some novel loci that were missed when considering main effects alone. PMID: 28813576
    4. ABHD2 gene single nucleotide polymorphisms, such as rs12442260 contribute to chronic obstructive pulmonary disease susceptibility in the Chinese Han population. PMID: 25880496
    5. ABHD2 is highly expressed in spermatozoa, binds progesterone, and acts as a progesterone-dependent lipid hydrolase by depleting the endocannabinoid 2-arachidonoylglycerol (2AG) from plasma membrane. PMID: 26989199
    6. Patients with selective immunoglobulin (Ig)A deficiency have a highly significant increase of homozygousity of HS1.2 allele *1, with an increase of 2.6-fold; the HS1.2 polymorphism influences Ig seric production, but not IgG switch. PMID: 20007591
    7. Our results showed that the ABHD2 was expressed in atherosclerotic lesions, and that the ABHD2 expression was significantly higher in the patients with UA than with SA. PMID: 17980156

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell projection, cilium, flagellum membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    AB hydrolase superfamily, AB hydrolase 4 family
  • 組織特異性：
    Present in sperm (at protein level).
  • 數據庫鏈接：

    HGNC: 18717

    OMIM: 612196

    KEGG: hsa:11057

    STRING: 9606.ENSP00000268129

    UniGene: Hs.122337



主站蜘蛛池模板： 影音先锋人妻每日资源站| 国内高清a自拍视频| 欧美性猛少妇xxxxx免费 | 国产精品美女www爽爽爽视频| 久久久精品欧美一区二区免费| 久久久久亚洲精品天堂| 国产精品久久人妻互换| 国产亚洲精品久久久久丝瓜| 欧美成人猛片aaaaaaa| 精品久久久久久无码人妻| 国产精品人成视频国模| 一本一本久久a久久综合精品 | 欧美精品videosex性欧美| 欧美两根一起进3p做受视频| 暖暖的在线观看日本社区| 高清乱码一区二区三区| 精品人妻二区中文字幕| 无码av免费一区二区三区| 亚洲欧美日本韩国| 激情综合亚洲色婷婷五月| 国产偷国产偷亚洲清高孕妇| 亚洲国产精品一区二区www| 欧美激情一区二区三区在线 | 人人妻人人爽人人做夜欢视频九色| 亚州性无码不卡免费视频 | 亚洲精品成人福利网站app| 成人性做爰aaa片免费| 乱人伦人妻中文字幕| 大桥未久亚洲一区二区| 亚洲中文无码mv| 亚洲熟妇丰满多毛xxxx| 亚洲第一av网站| 做爰高潮视频免费的看| a毛片免费全部播放自慰| 在线观看无码av网址| 欧美伊人久久大香线蕉综合| 少妇高潮无套内谢| 久久久久99精品成人品| 性高湖久久久久久久久| 日本不卡高字幕在线2019| 18禁亚洲深夜福利人口|