在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ABHD2 Antibody, HRP conjugated

ABHD2 Antibody, HRP conjugated

  • 中文名稱：
    ABHD2兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA001094LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ABHD2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ABHD2
  • 別名：
    ABHD2; LABH2; Monoacylglycerol lipase ABHD2; 2-arachidonoylglycerol hydrolase; Abhydrolase domain-containing protein 2; Acetylesterase; Lung alpha/beta hydrolase 2; Progesterone-sensitive lipase; Protein PHPS1-2
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Monoacylglycerol lipase ABHD2 protein (31-320AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation. May also play a role in smooth muscle cells migration.
  • 基因功能參考文獻：
    1. Suppression of ABHD2 in OVCA420 cells increased phosphorylated p38 and ERK, platinum resistance, and side population cells (p<0.01, respectively). Conversely, overexpression of ABHD2 decreased resistance to anoikis (p<0.05) and the amount of phosphorylated p38 and ERK in OVCA420 and SKOV3 cells. PMID: 27323405
    2. A mutant ABHD2 developed with alanine in place of Ser(207). PMID: 27247428
    3. These results show that joint tests of main effects and gene-gene interaction reveal associations at some novel loci that were missed when considering main effects alone. PMID: 28813576
    4. ABHD2 gene single nucleotide polymorphisms, such as rs12442260 contribute to chronic obstructive pulmonary disease susceptibility in the Chinese Han population. PMID: 25880496
    5. ABHD2 is highly expressed in spermatozoa, binds progesterone, and acts as a progesterone-dependent lipid hydrolase by depleting the endocannabinoid 2-arachidonoylglycerol (2AG) from plasma membrane. PMID: 26989199
    6. Patients with selective immunoglobulin (Ig)A deficiency have a highly significant increase of homozygousity of HS1.2 allele *1, with an increase of 2.6-fold; the HS1.2 polymorphism influences Ig seric production, but not IgG switch. PMID: 20007591
    7. Our results showed that the ABHD2 was expressed in atherosclerotic lesions, and that the ABHD2 expression was significantly higher in the patients with UA than with SA. PMID: 17980156

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell projection, cilium, flagellum membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    AB hydrolase superfamily, AB hydrolase 4 family
  • 組織特異性：
    Present in sperm (at protein level).
  • 數據庫鏈接：

    HGNC: 18717

    OMIM: 612196

    KEGG: hsa:11057

    STRING: 9606.ENSP00000268129

    UniGene: Hs.122337



主站蜘蛛池模板： 丰满岳跪趴高撅肥臀尤物在线观看| 亂倫近親相姦中文字幕| 亚洲男人成人性天堂网站| 日日碰狠狠添天天爽无码| 好爽好湿好硬好大免费视频| 久激情内射婷内射蜜桃人妖| 亚洲色偷拍另类无码专区| 麻豆精品传媒一二三区艾秋 | 久久www色情成人免费观看| 久久爱www人成狠狠爱综合网| 九月婷婷人人澡人人添人人爽 | 日本在线a一区视频高清视频| 免费看男女做爰爽爽视频| 黑人巨大精品欧美一区二区| av无码欧洲亚洲电影网| 日本亚欧热亚洲乱色视频| 精品国产综合区久久久久久| 精品久久久久中文字幕一区| 野外做受又硬又粗又大视幕| 巨熟乳波霸若妻在线播放| 人妻人人澡人人添人人爽| 日日噜噜夜夜爽爽| 少妇与子乱毛片| 好爽太紧了舒服视频| 尤物193在线人妻精品免费| 蜜桃av色偷偷av老熟女| 一本大道无码日韩精品影视丶 | 亲子乱子伦xxxx视频| 2020最新无码国产在线观看| 久久久久久人妻一区精品| 人妻少妇精品无码专区动漫| 人妻在卧室被老板疯狂进入| 亚洲熟妇无码八v在线播放| 在线观看国产日韩亚洲中| 亚洲级αv无码毛片久久精品| 久久超乳爆乳中文字幕| 97人妻天天摸天天爽天天| 中文字幕精品一二三四五六七八| 亚洲日韩日本中文在线| 天天澡天天揉揉av在线| 国内揄拍国产精品人妻门事件|