在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ABCB10 Antibody

ABCB10 Antibody

  • 中文名稱：
    ABCB10兔多克隆抗體
  • 貨號(hào)：
    CSB-PA001047GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    ABCB10
  • 別名：
    ABCB10; ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human ABCB10
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the export of an unknown physiological substrate from the mitochondrial matrix to the cytosol in an ATP-dependent manner. May also transport the heme analog Zn (II) mesoporphyrin (ZnMP) in an ATP dependent manner but can't export the heme precursor 5-aminolevulinic acid (ALA) from mitochondria. Plays a role in the early step of the heme biosynthetic process during insertion of iron into protoporphyrin IX (PPIX). In turn participates in hemoglobin synthesis and also protects against oxidative stress. In addition may be involved in mitochondrial unfolded protein response (UPRmt) signaling pathway, although ABCB10 probably does not participate in peptide export from mitochondria.
  • 基因功能參考文獻(xiàn)：
    1. Data suggest that ABCB10 silencing results in alteration in heme biosynthesis transcriptional profile due to repression by transcriptional regulator BACH1. (ABCB10 = ATP-binding cassette, sub-family B [MDR-TAP], member 10; BACH1 = BTB and CNC homology 1, basic leucine zipper transcription factor 1) PMID: 28808058
    2. ABCB10 is involved in unfolded protein response signaling pathway, although it probably does not participate in peptide export from mitochondria. PMID: 28315685
    3. ABCB10 is required for primitive erythropoiesis and to protect from oxidative stress associated with cardiac ischemia-reperfusion in mice. Antioxidants can rescue the defects associated with ABCB10 loss-of-function in mice. PMID: 22884976
    4. ABCB10 is not a heme exporter but is required for the early mitochondrial steps of heme biosynthesis. PMID: 23720443
    5. Data indicate that ABCB10 may exist in an open-inwards conformation when nucleotide is bound. PMID: 23716676
    6. Human mitochondrial ATP-binding cassette transporter ABCB10 is required for efficient red blood cell development. PMID: 22085049
    7. study of ABCB10 targeting, import, and dimerization PMID: 15215243

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ABC transporter superfamily, ABCB family, Mitochondrial peptide exporter (TC 3.A.1.212) subfamily
  • 組織特異性：
    Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 41

    OMIM: 605454

    KEGG: hsa:23456

    STRING: 9606.ENSP00000355637

    UniGene: Hs.17614



主站蜘蛛池模板： 色情久久久av熟女人妻网站| 亚洲熟妇无码久久精品| 大香伊蕉在人线国产网站首页| 人人玩人人添人人澡超碰偷拍| 99精品视频一区在线观看| 色哟哟免费视频播放网站| 三级网站视频在在线播放| 少妇与子乱毛片| 人妻无码视频一区二区三区| 放荡的美妇在线播放| 色妺妺av爽爽影院| 992tv精品视频tv在线观看| 国产成人综合久久免费导航| 蜜桃久久精品成人无码av| 国产无遮挡无码视频免费软件| 老司机久久99久久精品播放| 欧美色欧美亚洲日韩在线播放| 亚洲日韩中文字幕在线不卡最新| 任你躁在线精品免费| 国产免费mv大片人人电影播放器 | 亚洲天堂2017无码| 亚洲精品无码久久久久yw| 潮喷无码正在播放| 国产一区日韩二区欧美三区| 97精品人妻一区二区三区香蕉| 欧美丰腴丰满大屁股熟妇| 欲香欲色天天综合久久| 伊人色综合网久久天天| 日本xxxx片免费观看| 99久久婷婷国产综合精品青草免费| 久久综合九色综合欧美狠狠| 国产精品嫩草影院免费观看| 色婷婷五月综合色啪网| 99久久99久久精品免费看蜜桃| 国产伦精品一区二区三区| 伊人久久大香线蕉午夜av| 欧美日韩无砖专区一中文字| 久久不见久久见免费影院| 欧美乱码精品一区二区三区| 国产人妻精品区一区二区三区| 色久悠悠婷婷综合在线亚洲|