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A4GNT Antibody

  • 中文名稱:
    A4GNT兔多克隆抗體
  • 貨號:
    CSB-PA797885
  • 規格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from K562 cells, using A4GNT antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) A4GNT Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    A4GNT
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human A4GNT.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas.
  • 基因功能參考文獻:
    1. human alpha1,4-N-acetylglucosaminyltransferase (alpha4GnT) is responsible for O-glycan biosynthesis and has a role in preventing gastric cancer by inhibiting H. pylori infection and also suppressing tumor-promoting inflammation PMID: 22307328
    2. Up-regulation of alpha-1,4-N-acetylglucosaminyltransferase is associated with pancreatic cancer PMID: 16441422
  • 亞細胞定位:
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族:
    Glycosyltransferase 32 family
  • 組織特異性:
    Detected in stomach and pancreas.
  • 數據庫鏈接:

    HGNC: 17968

    KEGG: hsa:51146

    STRING: 9606.ENSP00000236709

    UniGene: Hs.278960



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