STK38L Monoclonal Antibody
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中文名稱：STK38L鼠單克隆抗體
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貨號：CSB-MA896491A0m
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規格：￥1,200
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圖片：
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Western Blot
Positive WB detected in: SKT38L antibody at 1:1000
Lane 1: HepG2 whole cell lysate
Lane 2: 293T whole cell lysate tissue
Lane 3: Jurkat whole cell lysate
Lane 4: Raw264.7 whole cell lysate
Lane 5: K562 whole cell lysate
Secondary
Goat polyclonal to Mouse IgG at 1/20000 dilution
Predicted band size: 55, 44 KDa
Observed band size: 55 KDa
Exposure time: 5min
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其他：
產品詳情
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產品描述：CUSABIO貨號：CSB-MA896491A0m STK38L單克隆抗體是針對絲氨酸/蘇氨酸蛋白激酶38L（STK38L）研發的高特異性科研試劑，該靶點屬于STE20蛋白激酶家族成員，在細胞周期調控、DNA損傷應答及細胞凋亡等關鍵生物學過程中發揮重要作用。本產品采用雜交瘤技術制備，經嚴格驗證具有優異的人源特異性，適用于Western Blot和ELISA兩種主流檢測平臺，可精準識別內源性STK38L蛋白。在基礎研究領域，該抗體廣泛應用于探究STK38L在腫瘤發生發展、神經退行性疾病及免疫調控中的分子機制，特別適用于信號通路解析、蛋白質相互作用研究以及疾病模型中的靶點表達水平檢測。通過優化的抗原表位設計和穩定的批間一致性，該抗體可為蛋白質印跡實驗提供清晰的條帶分辨效果，并在酶聯免疫實驗中展現高靈敏度的檢測性能，是探索STK38L功能研究的理想工具。科研人員可通過該產品深入解析STK38L在細胞應激反應、代謝調控中的分子網絡，為相關疾病機制研究提供可靠的技術支持。
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產品名稱：Mouse anti-Homo sapiens (Human) STK38L Monoclonal antibody
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Uniprot No.：
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基因名：STK38L
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別名：KIAA0965 antibody; NDR2 antibody; NDR2 protein kinase antibody; nuclear Dbf2 related 2 antibody; Nuclear Dbf2 related kinase 2 antibody; Nuclear Dbf2-related kinase 2 antibody; Serine/threonine protein kinase 38 like antibody; Serine/threonine-protein kinase 38-like antibody; ST38L_HUMAN antibody; Stk38l antibody
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宿主：Mouse
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反應種屬：Human
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免疫原：Recombinant Human Serine/threonine-protein kinase 38-like protein (212-464AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Monoclonal
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抗體亞型：IgG1
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純化方式：>95%, Protein G purified
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克隆號：7B12B3
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Involved in the regulation of structural processes in differentiating and mature neuronal cells.
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基因功能參考文獻：
- It was found that STK38L*I/D genotype had positive association with longevity in the ethnically homogeneous group of Tatars from the Republic of Bashkortostan, Russia. PMID: 28556638
- NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by triggering the switch in binding specificity of Rabin8 from PS to Sec15. PMID: 23435566
- Activation of NDR2 is a multistep process involving phosphorylation of the hydrophobic motif site Thr444/2 by MST3, autophosphorylation of Ser281/2, and binding of MOB1A. PMID: 16314523
- NDR2 is an upstream kinase of ARK5 that plays an essential role in tumor progression through ARK5 PMID: 16488889
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亞細胞定位：Cytoplasm. Cytoplasm, cytoskeleton. Membrane. Note=Associated with the actin cytoskeleton. Co-localizes with STK24/MST3 in the membrane.
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蛋白家族：Protein kinase superfamily, AGC Ser/Thr protein kinase family
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組織特異性：Ubiquitously expressed with highest levels observed in the thymus.
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數據庫鏈接：
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