CUSABIO貨號：CSB-MA145494 HK1單克隆抗體是針對己糖激酶1（Hexokinase 1）研發的高特異性科研工具，該靶點作為糖酵解通路的關鍵限速酶，催化葡萄糖轉化為葡萄糖-6-磷酸的起始反應，在細胞能量代謝調控中發揮核心作用，其表達異常與神經退行性疾病發生及腫瘤細胞Warburg效應密切相關。本產品經嚴格驗證適用于人類、犬類、豬、小鼠及大鼠等多物種樣本檢測，可兼容酶聯免疫吸附（ELISA）、蛋白質印跡（Western Blot）和免疫細胞化學（ICC）三大實驗平臺，為研究者提供跨物種比較研究的實驗便利。在神經科學領域可用于阿爾茨海默病模型中線粒體能量代謝研究，腫瘤生物學中適用于探究癌細胞糖酵解重編程機制，代謝性疾病方向可支持胰島素抵抗相關通路分析。該單抗具有高親和力和低交叉反應特性，能夠精準識別不同組織來源的HK1蛋白，為開展能量代謝調控、疾病模型構建及藥物靶點篩選等基礎研究提供可靠檢測工具。

HKI, HXK1, HK1-ta, HK1-tb, HK1-tc

Mouse

Human,Dog,Pig,Mouse,Rat

Purified recombinant HumanHK1 protein fragments expressed in E.coli.

Homo sapiens (Human)

Monoclonal

IgG1

Affinity purified

1G5

It differs from different batches. Please contact us to confirm it.

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol

ELISA,WB,ICC

Application	Recommended Dilution
WB	1:500-1:5000
ICC	1:50-1:200

ELISA Protocol
Western Blotting (WB) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.