CUSABIO貨號(hào)：CSB-MA136610 ATIC單克隆抗體是針對(duì)嘌呤生物合成關(guān)鍵酶ATIC研發(fā)的科研用抗體，該靶點(diǎn)在細(xì)胞代謝調(diào)控中發(fā)揮重要作用，通過催化5-氨基咪唑-4-甲酰胺核糖核苷（AICAR）轉(zhuǎn)化為甲酰基類似物（FAICAR），參與肌苷酸（IMP）合成的終末步驟。本產(chǎn)品采用雜交瘤技術(shù)制備，經(jīng)嚴(yán)格驗(yàn)證適用于Western Blot和ELISA檢測(cè)，具備優(yōu)異的人源與兔源樣本兼容性，能精準(zhǔn)識(shí)別天然構(gòu)象及變性狀態(tài)下的ATIC蛋白。其高親和力特性使其成為研究腫瘤細(xì)胞異常代謝、遺傳性嘌呤代謝疾病機(jī)制的理想工具，特別適用于檢測(cè)體外培養(yǎng)細(xì)胞系或?qū)嶒?yàn)動(dòng)物模型中的ATIC表達(dá)水平變化。作為科研級(jí)單抗產(chǎn)品，該抗體在驗(yàn)證基因功能、篩選藥物靶點(diǎn)等基礎(chǔ)研究中展現(xiàn)重要價(jià)值，配套提供的1mg規(guī)格凍干粉制劑便于長(zhǎng)期保存，經(jīng)復(fù)溶后即開即用，為研究者探索細(xì)胞增殖調(diào)控、代謝重編程等前沿領(lǐng)域提供可靠支持。

PURH, AICAR, AICARFT, IMPCHASE

Mouse

Human,Rabbit

Purified recombinant Human ATIC protein fragments expressed in E.coli.

Homo sapiens (Human)

Monoclonal

IgG1

Affinity purified

22G10

It differs from different batches. Please contact us to confirm it.

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

ELISA,WB

Application	Recommended Dilution
WB	1:500-1:5000

ELISA Protocol
Western Blotting (WB) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.