在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Rat macrophage inflammatory protein 2,MIP-2 ELISA kit

Rat macrophage inflammatory protein 2,MIP-2 ELISA kit

  • 中文名稱：
    大鼠巨噬細胞炎性蛋白2(MIP-2)酶聯免疫試劑盒
  • 貨號：
    CSB-E07419r
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產品詳情

  • 產品描述：
    大鼠巨噬細胞炎性蛋白2(MIP-2)酶聯免疫試劑盒（CSB-E07419r）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的CXCL2含量。CXCL2是重要靶點。它屬于趨化因子家族，在炎癥反應、腫瘤微環境等中起關鍵作用。其研究機制主要圍繞與受體結合，介導細胞趨化和激活，影響免疫細胞招募、腫瘤細胞遷移與增殖，目前是炎癥性疾病和腫瘤治療研究熱點。試劑盒檢測范圍為78 pg/mL-5000 pg/mL，靈敏度為19.5 pg/mL。適用于科研領域中對炎癥機制、藥物干預效果及疾病動物模型的研究，例如通過檢測組織勻漿中的MIP - 2水平評估局部炎癥程度，或分析血液樣本中趨化因子動態變化以探索全身性炎癥反應的調控通路。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    Cxcl2 ELISA kit; Cinc3 ELISA kit; Mip-2 ELISA kit; Mip2 ELISA kit; Scyb2C-X-C motif chemokine 2 ELISA kit; Cytokine-induced neutrophil chemoattractant 3 ELISA kit; CINC-3 ELISA kit; Macrophage inflammatory protein 2 ELISA kit; MIP2 ELISA kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Rattus norvegicus (Rat)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    78 pg/mL-5000 pg/mL
  • 靈敏度：
    19.5 pg/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Immunology
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：

    Intra-assay Precision (Precision within an assay): CV%<8%

    Three samples of known concentration were tested twenty times on one plate to assess.

    Inter-assay Precision (Precision between assays): CV%<10%

    Three samples of known concentration were tested in twenty assays to assess.

  • 線性度：

    To assess the linearity of the assay, samples were spiked with high concentrations of rat MIP-2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

    　

    Sample

    Serum(n=4)

    1:1

    Average %

    88

    Range %

    80-95

    1:2

    Average %

    90

    Range %

    85-99

    1:4

    Average %

    98

    Range %

    94-101

    1:8

    Average %

    93

    Range %

    86-98

  • 回收率：

    The recovery of rat MIP-2 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

    Sample Type

    Average % Recovery

    Range

    Serum (n=5)

    95

    89-98

    EDTA plasma (n=4)

    89

    84-97

  • 標準曲線：

    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

    pg/ml

    OD1

    OD2

    Average

    Corrected

    5000

    2.899

    2.934

    2.916

    2.778

    2500

    2.437

    2.567

    2.502

    2.364

    1250

    1.817

    1.828

    1.822

    1.684

    625

    1.228

    1.229

    1.229

    1.091

    312

    0.736

    0.721

    0.729

    0.591

    156

    0.445

    0.453

    0.449

    0.311

    78

    0.263

    0.254

    0.259

    0.121

    0

    0.141

    0.135

    0.138

    　

  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

靶點詳情

  • 最新研究進展：
    CXCL2是介導中性粒細胞、嗜酸性粒細胞和巨噬細胞趨化的重要化學趨化因子。最新研究表明，CXCL2在許多炎癥疾病中起重要作用，如哮喘、炎性腸病、骨關節炎等。此外，CXCL2還參與了腫瘤發生、發展和轉移過程，是潛在的抗腫瘤治療靶點。
  • 功能：
    Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. Contributes to neutrophil activation during inflammation.
  • 基因功能參考文獻：
    1. this study shows elevated expression of CINC-3 at the site of inflammation as well as their significant reflection in the circulation, thereby suggesting their frontline role in carrageenan-induced acute inflammation PMID: 27967265
    2. rutin is a potential protective agent in spinal cord injury enhancing the neurotrophic effect by inhibiting the expression of MIP-2 and activation of MMP-9, and downregulating the expression of p-Akt. PMID: 26502930
    3. The rat spiral ligament fibrocytes were found to release CXCL2 in response to nontypeable H. influenzae via activation of c-Jun, leading to the recruitment of polymorphonuclear cells to the cochlea. PMID: 22379036
    4. CsA has no significant effect on serum levels of MCP-1 and MIP-2 following renal transplantation in rats. PMID: 20034917
    5. Results identify FQHPSFI peptide may be used for the modulation of lipopolysaccharide-stimulated MIP-2 production in alveolar macrophagess. PMID: 20186460
    6. chemokine production by rat alveolar macrophages is inhibited by taurine chloramine PMID: 11716962
    7. Intratracheal LPS induced a significant increase in MIP-2 in bronchoalveolar lavage (BAL) fluid with no detectable MIP-2 in the plasma. PMID: 11837784
    8. demonstrated that the beta-glucan component of the Pneumocystis carinii cell wall is able to stimulate alveolar epithelial cells to produce MIP-2 PMID: 11906040
    9. role for the nitric oxide pathway in the overproduction of pro-inflammatory mediators IL-6 and MIP-2 during GBS-induced lung inflammation. PMID: 12661899
    10. junctional epithelium cells produced MIP-2 and CINC-2 in response to LPS stimulation, suggesting that MIP-2 and CINC-2 may be responsible for PMN migration toward the periodontal pathogen and may play an important role in the initiation of inflammation PMID: 15045510
    11. macrophage inflammatory protein 2 mediates platelet-activating factor-induced intestinal injury PMID: 15319184
    12. no significant differences were detected for MIP-2 levels in diabetic rats when compared with non-diabetic rats after hypoxia PMID: 16132691
    13. Following cecal ligation and puncture Cxcl2 production increases in the lung, setting the stage for neutrophil accumulation in lung during sepsis. PMID: 16818791
    14. MIP-2/CXCL2 and MCP-1/CCL2 are increased after injury, and neurons appear to be the source of this expression. Chemokine expression was selectively inhibited by dexamethasone. PMID: 19210118

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Intercrine alpha (chemokine CxC) family
  • 組織特異性：
    At least expressed in the lung and trachea.
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲vs日韩vs欧美vs久久| 午夜福利无码不卡在线观看| 波多野结衣中文字幕一区二区三区| 丁香色婷婷国产精品视频| 狠狠躁夜夜躁人人爽天天| 久久国产欧美成人av| 久久婷婷综合缴情亚洲狠狠_| 亚洲乱码中文字幕手机在线| 蜜臀av无码精品人妻色欲| 精品国产欧美一区二区| 国产av激情久久无码天堂| 欧美日韩在手机线旡码可下载 | 久久精品国产第一区二区三区| 亚洲精品人成网线在播放va| 亚洲人成网站在小说| 欧美成人免费一区二区| 国模小婕私拍鲜嫩玉门| 又爆又大又粗又硬又黄的a片| 中国白嫩丰满人妻videos| 日韩熟女精品一区二区三区 | 激情文学小说区另类小说同性| 特级西西人体444www高清大胆| 色94色欧美sute亚洲线路二 | 亚洲精品白浆高清久久久久久| 久久五月丁香激情综合| 久久99精品久久久久久蜜芽 | 美女扒开大腿让男人桶| 婷婷五月深深久久精品| 久久午夜私人影院| 99精品免视看| 巨胸不知火舞露双奶头无遮挡| 亚洲午夜私人影院在线观看| 亚洲麻豆av成本人无码网站| 国产成人av男人的天堂| 忍不住的亲子中文字幕| 精品国产三级a在线观看| 2021精品亚洲中文字幕| 熟女人妻水多爽中文字幕| 国产成人无码精品久久久性色 | 日韩人妻无码一区二区三区| 一区二区三区波多野结衣在线观看|