在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Rat Neurotrophin 4,NT-4 ELISA KIT

  • 中文名稱:
    大鼠神經營養因子4(NT-4)酶聯免疫試劑盒
  • 貨號:
    CSB-E04691r
  • 規格:
    96T/48T
  • 價格:
    ¥3900/¥2500
  • 其他:

產品詳情

  • 產品描述:
    大鼠神經營養因子4(NT-4)酶聯免疫試劑盒(CSB-E04691r)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的NTF4含量。NTF4(神經生長因子-4)是一種神經營養因子,由NTF4基因編碼,主要通過TrkB受體信號傳導。研究發現,NTF4在神經發生中起關鍵作用,通過調節Stat3和PKB/Akt活性,抑制Il6和Notch信號通路,促進神經干細胞分化為神經元。試劑盒檢測范圍為47 pg/mL-3000 pg/mL,本試劑盒適用于神經發育、損傷修復機制研究,以及神經退行性疾病模型、藥物干預實驗中NT - 4的動態監測,例如腦組織、外周神經或血液樣本的分析。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
  • 別名:
    Ntf4 ELISA Kit; Nt4 ELISA Kit; Ntf5 ELISA Kit; Neurotrophin-4 ELISA Kit; NT-4 ELISA Kit; Neurotrophin-5 ELISA Kit; NT-5 ELISA Kit; Neutrophic factor 4 ELISA Kit
  • 縮寫:
  • Uniprot No.:
  • 種屬:
    Rattus norvegicus (Rat)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    47 pg/mL-3000 pg/mL
  • 靈敏度:
    11.75 pg/mL
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Neuroscience
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 精密度:
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度:
    To assess the linearity of the assay, samples were spiked with high concentrations of rat NT-4 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
     SampleSerum(n=4)
    1:1Average %86
    Range %82-94
    1:2Average %93
    Range %88-98
    1:4Average %96
    Range %90-102
    1:8Average %99
    Range %95-104
  • 回收率:
    The recovery of rat NT-4 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9690-102
    EDTA plasma (n=4)10095-105
  • 標準曲線:
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected
    30002.268 2.250 2.259 2.150
    15001.845 1.871 1.858 1.749
    7501.464 1.492 1.478 1.369
    3751.135 1.149 1.142 1.033
    187.50.704 0.724 0.714 0.605
    940.438 0.457 0.448 0.339
    470.287 0.294 0.291 0.182
    00.108 0.110 0.109  
  • 數據處理:
  • 貨期:
    3-5 working days

引用文獻

產品評價

靶點詳情

  • 功能:
    Could serve as a target-derived trophic factor for sensory and sympathetic neurons.
  • 基因功能參考文獻:
    1. The neuroprotective effect of NT-4 on retinas cultured under diabetic stress correlates with suppression of PERK kinase and transcription factor CHOP. PMID: 21767604
    2. alteration of NT-4 protein levels and gene expression in brain stem, cerebellum and cerebral hemisphere in context of ecstasy dependence; results show chronic administration of ecstasy significantly increased NT-4 gene expression in these areas of brain PMID: 21273656
    3. NT-4, alone or when co-expressed with brain-derived neurotrophic factor, is processed within and secreted by the constitutive secretory pathway PMID: 12970359
    4. The results indicate that oleic acid behaves as a neurotrophic factor, inducing GAP-43 expression through a PKC-mediated mechanism that is not mediated by other neurotrophic factors but that is strongly synergized by NT-3 and NT-4/5. PMID: 14519521
    5. NT-4 significantly improved slow motor unit recovery, and provides a basis for therapies intended to aid the functional recovery of muscles after denervating injury. PMID: 14622146
    6. BDNF and NT-4 expression could be modulated by activity of spinal circuitry and further support putative involvement of the endogenous neurotrophins in mechanisms of spinal neuroplasticity. PMID: 15193526
    7. Transcellular induction of neuropeptide Y expression by NT4 and BDNF. PMID: 15703301
    8. NT-4 regulates proliferation and differentiation of the dental epithelium and promotes production of the enamel matrix PMID: 18045880
    9. Analysis of neurotrophin expression in dentate gyrus dosen't reveal an expression change of Ntf4 in a genetically hypertensive strain of Wistar rat. PMID: 18957307

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    NGF-beta family
  • 組織特異性:
    Expressed in thymus, muscle, ovary, brain, heart, stomach and kidney. Expressed in both embryo and adult tissues.
  • 數據庫鏈接:


主站蜘蛛池模板: 香蕉欧美成人精品a∨在线观看| 日本视频高清一道一区| 加勒比一本heyzo高清视频| 国产亚洲综合网曝门系列| 久久综合久久爱久久综合伊人| 国产精品久久久一区二区三区 | 丰满少妇69激情啪啪无| 亚洲国产精品成人一区二区在线| 韩国无码av片在线观看| 亚洲色成人一区二区三区| 好男人社区在线www| 国产三级久久久精品麻豆三级 | 亚洲精品久久久久久中文传媒| 舌头伸进去搅动好爽视频| 午夜日本大胆裸艺术| 全黄h全肉边做边吃奶视频| 亚洲精品无码成人网站| 亚洲中国最大av网站| 久久久久人妻一区二区三区| 久久99成人免费| 亚洲精品欧美精品日韩精品| 亚洲综合久久无码色噜噜| 色插图午夜影院| 色欲精品国产一区二区三区av | 人妻 校园 激情 另类| 亚洲人成色4444在线观看| 午夜好爽好舒服免费视频| 日本www网站色情乱码| 99久久婷婷国产综合精品青草免费| 欧美日韩精品久久久免费观看| 玖玖玖国产精品视频| 亚洲男人的天堂www| 护士奶头又白又大又好摸视频| 成av人电影在线观看| 日本欧美亚洲中文在线观看| 99久久99久久精品免费观看| 永久免费无码日韩视频| 亚洲午夜成人精品无码app| 国产亚洲精品a在线观看下载| 亚洲熟妇无码av在线播放| 国产午费午夜福利200集|