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Rat Follistatin-related protein 1(FSTL1) ELISA kit

  • 中文名稱:
    大鼠卵泡抑素相關(guān)蛋白1(FSTL1)酶聯(lián)免疫試劑盒
  • 貨號:
    CSB-EL009025RA
  • 規(guī)格:
    96T/48T
  • 價格:
    ¥3600/¥2500
  • 促銷:
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品描述:
    大鼠卵泡抑素相關(guān)蛋白1(FSTL1)酶聯(lián)免疫試劑盒(CSB-EL009025RA)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿,組織勻漿樣本中的FSTL1含量。試劑盒檢測范圍為15.6 ng/mL-1000 ng/mL,適用于基礎(chǔ)科研場景,例如探究FSTL1在大鼠模型中的表達(dá)調(diào)控及其與炎癥、纖維化或代謝性疾病的相關(guān)性研究。可滿足細(xì)胞實驗、動物模型或組織樣本分析等科研需求。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名:
    Fstl1 ELISA kit; FrpFollistatin-related protein 1 ELISA kit; Follistatin-like protein 1 ELISA kit
  • 縮寫:
    FSTL1
  • Uniprot No.:
  • 種屬:
    Rattus norvegicus (Rat)
  • 樣本類型:
    serum, plasma,tissue homogenates
  • 檢測范圍:
    15.6 ng/mL-1000 ng/mL
  • 靈敏度:
    3.9 ng/mL
  • 反應(yīng)時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領(lǐng)域:
    Cardiovascular
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 數(shù)據(jù)處理:
  • 貨期:
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 功能:
    Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes. Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors.
  • 基因功能參考文獻(xiàn):
    1. exercise increased the cross-sectional area of myocytes and FSTL1 expression. Importantly, exercise increased circulating FSTL1 levels, which were positively correlated with the skeletal muscle FSTL1 expression and negatively correlated with heart fibrosis PMID: 27561749
    2. Decreased expression of Fstl1 in alveolar epithelium may disrupt alveolarization and pulmonary surfactant production, thus contributing to the development of pulmonary hypertension in the nitrofen-induced rat congenital diaphragmatic hernia model. PMID: 28188034
    3. our findings indicate that FSTL1 may contribute to neuronal survival after brain ischemia PMID: 25139876
    4. Characterization of follistatin-related gene: effects of estrous cycle stage and pregnancy on its messenger RNA expression in reproductive tissues. PMID: 12493714
    5. Expression levels of FLRG protein are significantly increased in brain damaged regions after penetrating injury; specifically, FLRG protein is colocalized in glial fibrillary acidic protein-positive reactive astroglial cells. PMID: 12645077
    6. Follistatin-like 1 (FSTL1) transcript is overexpressed in tolerated allografts compared to rejected allografts or syngeneic grafts PMID: 18925901

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  • 亞細(xì)胞定位:
    Secreted.
  • 數(shù)據(jù)庫鏈接:


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