-
中文名稱:大鼠嗜酸粒細胞趨化蛋白Eotaxin 1(Eotaxin 1/CCL11)酶聯免疫試劑盒
-
貨號:CSB-E07319r
-
規格:96T/48T
-
價格:¥3200/¥2500
-
其他:
產品詳情
-
產品描述:大鼠嗜酸粒細胞趨化蛋白Eotaxin 1(Eotaxin 1/CCL11)酶聯免疫試劑盒(CSB-E07319r)檢測血清、血漿、組織勻漿樣本中的CCL11含量。CCL11是一種重要的靶點。它在免疫調節等生理過程中發揮作用。相關研究關注其在炎癥反應、趨化免疫細胞遷移等機制,探索其在疾病如過敏性疾病、神經系統疾病等發病中的作用,有望為開發針對CCL11的治療手段提供依據。試劑盒檢測范圍為15.6 pg/ml-1000 pg/ml,適用于呼吸道疾病模型研究、炎癥機制探索及藥物干預效果評估等科研場景本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
-
別名:Ccl11 ELISA Kit; Scya11Eotaxin ELISA Kit; C-C motif chemokine 11 ELISA Kit; Eosinophil chemotactic protein ELISA Kit; Small-inducible cytokine A11 ELISA Kit
-
縮寫:
-
Uniprot No.:
-
種屬:Rattus norvegicus (Rat)
-
樣本類型:serum, plasma, tissue homogenates
-
檢測范圍:15.6 pg/ml -1000 pg/ml
-
靈敏度:3.9 pg/ml
-
反應時間:1-5h
-
樣本體積:50-100ul
-
檢測波長:450 nm
-
研究領域:Immunology
-
測定原理:quantitative
-
測定方法:Sandwich
-
精密度:
-
線性度:
-
回收率:
-
標準曲線:
-
數據處理:
-
貨期:3-5 working days
引用文獻
- Protein tyrosine phosphatase 11 acts through RhoA/ROCK to regulate eosinophil accumulation in the allergic airway Xu C, et al,Faseb Journal,2019
相關產品
靶點詳情
-
功能:In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions), but not lymphocytes, macrophages or neutrophils. Binds to CCR3.
-
基因功能參考文獻:
- our data suggest that the CCL11-CCR3 interaction mainly activates PI3K/Akt signal transduction pathway in HUVECs. PMID: 28279120
- Iddm30 controls pancreatic expression of Ccl11 (Eotaxin) and the Th1/Th2 balance within the insulitic lesions. PMID: 24646746
- Tripterine can inhibit expression of Eotaxin by restraining the activation of NF-kappaB in the nasal musoca of rats with allergic rhinitis. PMID: 23272499
- expression of Ccl11 associates with immune response modulation in experimental autoimmune encephalomyelitis PMID: 22815714
- Intervention of PRMT1 activity can abrogate IL-4-dependent eotaxin-1 production to influence the pulmonary inflammation with eosinophil infiltration. PMID: 22387551
- The expression of Eotaxin in nasal lavage fluid and nasal mucosa increased after treatment of allergic rhinitis with histamine. PMID: 20359111
- The expression of Eotaxin in nasal mucosa increased, and the expression of CCR3 in bone marrow increased in the model of allergic rhinitis. PMID: 16722399
- Suppression of eotaxin by CpG DNA reduced the symptoms of experimental allergic rhinitis. PMID: 16838745
- Targeting CCL11 with monoclonal antibodies possibly results in decreased myocardial fibrosis and improves contractile function after heart transplantation ub rats. PMID: 20832583
- Galectin-3 inhibited expression of eotaxin and IL5, potentially suppressing eosinophilic inflammation in asthma. PMID: 17074272
- Eotaxin is upregulated in the pancreatic lymph nodes and may play a role in early disease pathogenesis of type 1 diabetes mellitus in the BioBreeding rat model. PMID: 15557196
- In a model of ongoing acute heart transplant rejection in the rat, we found eotaxin mRNA expression within infiltrating macrophages, but not in mast cells PMID: 19631640
顯示更多
收起更多
-
亞細胞定位:Secreted.
-
蛋白家族:Intercrine beta (chemokine CC) family
-
數據庫鏈接:
Most popular with customers
-
Human Transforming Growth factor β1,TGF-β1 ELISA kit
Detect Range: 23.5 pg/ml-1500 pg/ml
Sensitivity: 5.8 pg/ml
-
-
-
Mouse Tumor necrosis factor α,TNF-α ELISA Kit
Detect Range: 7.8 pg/ml-500 pg/ml
Sensitivity: 1.95 pg/ml
-
-
-
-