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中文名稱:大鼠皮質酮(CORT)酶聯免疫試劑盒
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貨號:CSB-E07014r
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規格:96T/48T
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價格:¥3900/¥2500
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其他:
產品詳情
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產品描述:大鼠皮質酮/腎上腺酮(CORT)酶聯免疫試劑盒(CSB-E07014r)為競爭法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的CORT含量。CORT即皮質酮,是一種重要的糖皮質激素。它參與機體應激反應與代謝調節等生理過程。研究機制上,主要通過與細胞內糖皮質激素受體結合,調控相關基因表達,影響細胞功能,在神經、內分泌等多系統中發揮關鍵作用。試劑盒檢測范圍為0.2 ng/mL-40 ng/mL,支持科研人員開展神經內分泌機制研究、慢性應激模型評估、代謝綜合征相關實驗及藥物干預效果驗證等領域的探索,為行為學實驗、神經藥理學研究和激素調控機制探索提供可靠的數據支持。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
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別名:N/A
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縮寫:CORT
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種屬:Rattus norvegicus (Rat)
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樣本類型:serum, plasma, tissue homogenates
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檢測范圍:0.2 ng/mL-40 ng/mL
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靈敏度:0.1 ng/mL
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反應時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領域:Signal Transduction
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測定原理:quantitative
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測定方法:Competitive
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精密度:
Intra-assay Precision (Precision within an assay): CV%<15% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<15% Three samples of known concentration were tested in twenty assays to assess. -
線性度:
To assess the linearity of the assay, samples were spiked with high concentrations of rat CORT in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:1 Average % 84 Range % 80-91 1:2 Average % 90 Range % 85-95 1:4 Average % 97 Range % 92-103 1:8 Average % 105 Range % 100-112 -
回收率:
The recovery of rat CORT spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 95 89-99 EDTA plasma (n=4) 92 88-97 -
標準曲線:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. ng/ml OD1 OD2 Average 40 0.138 0.132 0.135 10 0.239 0.258 0.249 3.2 0.504 0.509 0.507 0.8 0.939 1.009 0.974 0.2 1.419 1.424 1.422 0 2.154 2.159 2.157 -
數據處理:
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貨期:3-5 working days
引用文獻
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- Aging induced Hematological, Anthropometrical, Biochemical, and Reproductive Changes in Male Rats KH Mohamed,Zagazig Veterinary Journal,2024
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- Environmental enrichment and the combined interventions of EE and metformin enhance hippocampal neuron survival and hippocampal-dependent memory in type 2 diabetic rats under stress through the BDNF-TrkB signaling pathways TR Ismail,Biomedicine & pharmacotherapy,2024
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- Increase of circulating cfDNA by chronic training or overtraining in human and rat and its possible mechanisms LJ Yin,Science & Sports,2023
- Association analysis of gut microbiota-metabolites-neuroendocrine changes in male rats acute exposure to simulated altitude of 5500 m J Wang,Scientific reports,2023
- Can Resveratrol Influence the Activity of 11β-Hydroxysteroid Dehydrogenase Type 1? A Combined In Silico and In Vivo Study J Novak,Pharmaceuticals,2023
- Paradoxical Anxiety Level Reduction in Animal Chronic Stress: A Unique Role of Hippocampus Neurobiology Vadim Tseilikman,International Journal of Molecular Sciences,2022
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- Norepinephrine in the dentate gyrus is involved in spatial learning and memory alteration induced by chronic restraint stress in aged rats FX Wang,Neuroreport,2020
- Effect of Light-Dark Cycle Misalignment on the Hypothalamic-Pituitary-Gonadal Axis, Testicular Oxidative Stress, and Expression of Clock Genes in Adult Male Rats A Moustafa,International journal of endocrinology,2020
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- Mechanisms of Stress-Induced Spermatogenesis Impairment in Male Rats Following Unpredictable Chronic Mild Stress (uCMS) Zou P, et al,International Journal of Molecular Sciences,2019
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- Acute restraint stress alters food-foraging behavior in rats: Taking the easier Way while suffered Tu BX,Brain Research Bulletin,2019
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- Acupuncture alters pro-inflammatory cytokines in the plasma of maternally separated rat pups Wang Z.et al,Chin J Integr Med. ,2017
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相關產品
靶點詳情
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最新研究進展:CORT是一種重要的激素,可以影響多種生理過程,如免疫和應激反應。最近的研究表明,CORT可以通過影響免疫細胞的活動來調節免疫反應。例如,在炎癥過程中,CORT可以抑制炎癥介質的產生,從而緩解炎癥反應。此外,CORT也被認為是抑制免疫系統過度激活的重要因素之一。最近的研究還表明,CORT可能在多種神經系統疾病中具有治療潛力,例如抑郁癥和焦慮癥等。
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