在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Rat Chitinase-3-like protein 1(CHI3L1) ELISA kit

Rat Chitinase-3-like protein 1(CHI3L1) ELISA kit

  • 中文名稱：
    大鼠幾丁質(zhì)酶3樣蛋白1(CHI3L1)酶聯(lián)免疫試劑盒
  • 貨號(hào)：
    CSB-EL005346RA
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    大鼠幾丁質(zhì)酶3樣蛋白1(CHI3L1)酶聯(lián)免疫試劑盒（CSB-EL005346RA）檢測(cè)血清、血漿、組織勻漿樣本中的CHI3L1含量。CHI3L1是一個(gè)重要靶點(diǎn)。它與多種疾病發(fā)生發(fā)展相關(guān)，如炎癥、腫瘤等。研究機(jī)制上，其可能通過參與細(xì)胞增殖、遷移、凋亡等過程，影響疾病進(jìn)程，目前圍繞它開展的研究有助于深入理解疾病發(fā)病機(jī)理，為相關(guān)疾病治療提供新思路。試劑盒檢測(cè)范圍為4.7 ng/ml- 300 ng/ml，靈敏度為1.17 ng/ml。研究呼吸系統(tǒng)疾病、肝纖維化及腫瘤微環(huán)境等病理機(jī)制；炎癥相關(guān)疾病模型構(gòu)建、纖維化進(jìn)程評(píng)估及藥物干預(yù)效果研究；探索CHI3L1在生理病理過程中的分子機(jī)制本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    Chi3l1Chitinase-3-like protein 1 ELISA kit; Cartilage glycoprotein 39 ELISA kit; CGP-39 ELISA kit; GP-39 ELISA kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Rattus norvegicus (Rat)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測(cè)范圍：
    4.7 ng/ml - 300 ng/ml
  • 靈敏度：
    1.17 ng/ml
  • 反應(yīng)時(shí)間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測(cè)波長(zhǎng)：
    450 nm
  • 研究領(lǐng)域：
    Signal Transduction
  • 測(cè)定原理：
    quantitative
  • 測(cè)定方法：
    Sandwich
  • 精密度：

    Intra-assay Precision (Precision within an assay): CV%<8%

    Three samples of known concentration were tested twenty times on one plate to assess.

    Inter-assay Precision (Precision between assays): CV%<10%

    Three samples of known concentration were tested in twenty assays to assess.

  • 線性度：

    To assess the linearity of the assay, samples were spiked with high concentrations of rat CHI3L1 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

    　

    Sample

    Serum(n=4)

    1:1

    Average %

    103

    Range %

    99-108

    1:2

    Average %

    98

    Range %

    94-102

    1:4

    Average %

    93

    Range %

    89-97

    1:8

    Average %

    90

    Range %

    86-98

  • 回收率：

    The recovery of rat CHI3L1 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

    Sample Type

    Average % Recovery

    Range

    Serum (n=5)

    95

    90-100

    EDTA plasma (n=4)

    89

    84-95

  • 標(biāo)準(zhǔn)曲線：

    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

    ng/ml

    OD1

    OD2

    Average

    Corrected

    300

    2.486

    2.358

    2.422

    2.241

    150

    2.043

    1.931

    1.987

    1.806

    75

    1.241

    1.329

    1.285

    1.104

    37.5

    0.765

    0.803

    0.784

    0.603

    18.75

    0.413

    0.427

    0.420

    0.239

    9.4

    0.339

    0.345

    0.342

    0.161

    4.7

    0.231

    0.224

    0.228

    0.047

    0

    0.180

    0.182

    0.181

    　

  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
  • 基因功能參考文獻(xiàn)：
    1. Results showed that protein and mRNA levels of CHI3L1 decreased in normal cartilage but increased in osteoarthritic cartilage. PMID: 26978347
    2. NGF-treated tissue showed increased expression of CHI3L1 which was inhibited by the presence of Ro 08-2750 in intervertebral disk cells. PMID: 25062286
    3. Data show that hepatic CD14+ cells are an YKL-40(Chi3L1)mRNA and protein source in acute and chronic liver injury, with expression patterns similar to growth factors implicated in inflammation-fibrogenesis PMID: 21987626
  • 亞細(xì)胞定位：
    Secreted, extracellular space. Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum.
  • 蛋白家族：
    Glycosyl hydrolase 18 family
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 久久精品九九热无码免贵| 国产成人年无码av片在线观看| 日本xxxx少妇高清hd| 无码人妻aⅴ一区二区三区69岛| 艳妇乳肉豪妇荡乳xxx| av亚欧洲日产国码无码| 中文字幕丰满乱子无码视频| 男女啪啪永久免费网站| 亚洲欧美日韩国产精品一区二区 | 亚洲精品欧美二区三区中文字幕| 好男人社区资源| 亚洲国产成人爱av在线播放| 天堂亚洲国产中文在线| 国产xxxx99真实实拍| 国产精品无码一区二区桃花视频| 久久无码中文字幕无码| 国产精品无码a∨麻豆| 性一交一乱一伦一色一情孩交 | 开心色怡人综合网站| 精品少妇爆乳无码av无码专区| 日本极品少妇xxxx| 欧美性色大片在线观看| 肉色丝袜足j视频国产| 欧美性猛交aaaa片黑人| 成av人电影在线观看| 风韵犹存丰满大屁股熟妇视频| 日韩中文无码有码免费视频| 亚洲午夜福利在线观看| 国产精品一区波多野结衣| 四虎www永久在线精品| 亚洲中文字幕无码中文字| 亚洲第一成人网站在线播放| 无码8090精品久久一区| 五月综合激情婷婷六月色窝| 风韵丰满熟妇啪啪区老老熟妇| 久久亚洲中文字幕精品一区| 国产制服丝袜欧美在线观看| 久久综合噜噜激激的五月天| 欧美亚洲日韩国产网站| 国产成人精品999视频| 亚洲日韩一区二区三区|