在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Mouse β-hexosaminidase A,β-Hex A ELISA Kit

  • 中文名稱:
    小鼠β氨基己糖苷酶A(β-Hex A)酶聯免疫試劑盒
  • 貨號:
    CSB-E04818m
  • 規格:
    96T/48T
  • 價格:
    ¥3800/¥2500
  • 其他:

產品詳情

  • 產品描述:
    小鼠β氨基己糖苷酶A(β-Hex A)酶聯免疫試劑盒(CSB-E04818m)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的HEXA含量。HEXA是一種溶酶體酶,負責分解GM2神經節苷脂,維持細胞內環境穩定。其突變會導致GM2神經節苷脂在細胞內積累,引發泰薩二氏病等疾病。研究HEXA的機制,旨在開發治療相關遺傳性神經退行性疾病的藥物。試劑盒檢測范圍為3.12 μU/mL-200 μU/mL,適用于研究β-Hex A在代謝性疾病模型小鼠中的表達調控、基因敲除/過表達動物模型的酶活性驗證,以及藥物干預或病理條件下溶酶體功能的評估等科研場景。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
  • 別名:
    Hexa ELISA Kit; Beta-hexosaminidase subunit alpha ELISA Kit; EC 3.2.1.52 ELISA Kit; Beta-N-acetylhexosaminidase subunit alpha ELISA Kit; Hexosaminidase subunit A ELISA Kit; N-acetyl-beta-glucosaminidase subunit alpha ELISA Kit
  • 縮寫:
  • Uniprot No.:
  • 種屬:
    Mus musculus (Mouse)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    3.12 μU/mL-200 μU/mL
  • 靈敏度:
    0.78 μU/mL
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Neuroscience
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 精密度:
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度:
    To assess the linearity of the assay, samples were spiked with high concentrations of mouse β-Hex A in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:10Average %92
    Range %85-100
    1:20Average %93
    Range %87-98
    1:40Average %90
    Range %86-100
    1:80Average %90
    Range %86-98
  • 回收率:
    The recovery of mouse β-Hex A spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9789-101
    EDTA plasma (n=4)9592-98
  • 標準曲線:
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    μU/mlOD1OD2AverageCorrected
    2002.542 2.517 2.530 2.386
    1002.073 2.101 2.087 1.943
    501.452 1.464 1.458 1.314
    250.942 0.961 0.952 0.808
    12.50.416 0.402 0.409 0.265
    6.250.325 0.311 0.318 0.174
    3.120.247 0.237 0.242 0.098
    00.146 0.141 0.144
  • 數據處理:
  • 貨期:
    3-5 working days

產品評價

靶點詳情

  • 功能:
    Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme S is as active as the isozyme A on the anionic bis-sulfated glycans, the chondroitin-6-sulfate trisaccharide (C6S-3), and the dermatan sulfate pentasaccharide, and the sulfated glycosphingolipid SM2. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A.
  • 基因功能參考文獻:
    1. Neu4 is not the only sialidase contributing to the metabolic bypass in Hexa(-/-) mice. PMID: 20862357
  • 亞細胞定位:
    Lysosome.
  • 蛋白家族:
    Glycosyl hydrolase 20 family
  • 組織特異性:
    Ubiquitous. Most abundant in testis, adrenal, epididymis and heart. Low levels seen in the liver.
  • 數據庫鏈接:

    KEGG: mmu:15211

    STRING: 10090.ENSMUSP00000026262

    UniGene: Mm.2284



主站蜘蛛池模板: 欧美午夜理伦三级在线观看| 天天天天做夜夜夜做| 色偷偷人人澡人人爽人人模| 色噜噜狠狠一区二区三区| 国产精品久久久久久久免费看| 国产高潮国产高潮久久久| 成 人色 网 站 欧美大片在线观看| 无码国产片观看| 99国精品午夜福利视频不卡 | 一本色道久久综合亚州精品蜜桃| 国产好大好硬好爽免费视频| 成人欧美一区二区三区| 红杏亚洲影院一区二区三区| 国产成人8x人在线视频软件| 亚洲国产成人爱av网站| 国产av丝袜旗袍无码网站| 久久久久无码中| 亚洲已满18点击进入在线观看| 无码毛片一区二区本码视频| 真人与拘做受免费视频| 亚洲一卡2卡3卡4卡 精品| 国产精品无码永久免费888| 欧洲精品免费一区二区三区| 人人澡超碰碰97碰碰碰| 亚洲午夜理论片在线观看 | 好爽好舒服要高潮了视频| 国产精品久久久久久亚洲毛片| 久久99精品久久久久久噜噜| 国产做爰xxxⅹ久久久小说| 国产精品区一区二区三在线播放 | 欧美精品a∨在线观看| 色综合久久久无码网中文| 国产精品va在线观看无码| 免费无码黄动漫十八禁| 国产午夜鲁丝片av无码| 午夜dv内射一区区| 亚洲和欧洲一码二码区别7777| 欧美人与动牲交欧美精品| 日本精品高清一区二区| 久久久中文久久久无码| 性xxx欧美老妇5060.70|