在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Mouse coagulation factor Ⅶ,FⅦ ELISA Kit

Mouse coagulation factor Ⅶ,FⅦ ELISA Kit

  • 中文名稱：
    小鼠凝血因子Ⅶ(FⅦ)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-E17817m
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    小鼠凝血因子Ⅶ(FⅦ)酶聯(lián)免疫試劑盒（CSB-E17817m）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的F7含量。小鼠凝血因子Ⅶ（FⅦ）是凝血系統(tǒng)中重要的因子，其基因剔除小鼠模型在研究凝血機制和抗血栓藥物靶點方面具有重要作用。FⅦ基因剔除小鼠因缺乏FⅦ而表現(xiàn)出嚴重的出血傾向，為研究凝血因子功能提供了有力工具。試劑盒檢測范圍為0.45 ng/mL-30 ng/mL，該產(chǎn)品適用于凝血機制基礎(chǔ)研究、抗凝藥物開發(fā)評估以及血栓性疾病或出血性疾病小鼠模型中FⅦ蛋白水平的動態(tài)監(jiān)測，為研究凝血調(diào)控網(wǎng)絡(luò)提供可靠工具。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    F7 ELISA Kit; Cf7 ELISA Kit; Coagulation factor VII ELISA Kit; EC 3.4.21.21 ELISA Kit; Serum prothrombin conversion accelerator) [Cleaved into: Factor VII light chain; Factor VII heavy chain] ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Mus musculus (Mouse)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    0.45 ng/mL-30 ng/mL
  • 靈敏度：
    0.11 ng/mL
  • 反應(yīng)時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Blood Coagulation
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%        
    Three samples of known concentration were tested twenty times on one plate to assess.    
    Inter-assay Precision (Precision between assays): CV%<10%        
    Three samples of known concentration were tested in twenty assays to assess.      
                   
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of mouse FⅦ in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.  
    　 Sample Serum(n=4)    
    1:1000 Average % 92    
    Range % 86-96    
    1:2000 Average % 97    
    Range % 92-102    
    1:4000 Average % 93    
    Range % 88-97    
    1:8000 Average % 89    
    Range % 84-94    
  • 回收率：
    The recovery of mouse FⅦ spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.  
     
    Sample Type Average % Recovery Range    
    Serum (n=5) 92 88-95    
    EDTA plasma (n=4) 108 103-114    
                   
                   
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.  
     
    ng/ml OD1 OD2 Average Corrected    
    30 2.468 2.445 2.457 2.324    
    15 2.115 1.951 2.033 1.900    
    7.5 1.503 1.440 1.472 1.339    
    3.75 0.845 0.790 0.818 0.685    
    1.8 0.626 0.593 0.610 0.477    
    0.9 0.381 0.362 0.372 0.239    
    0.45 0.274 0.252 0.263 0.130    
    0 0.137 0.129 0.133 　    
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 功能：
    Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
  • 基因功能參考文獻：
    1. Leu8 is crucial for FVIIa-EPCR binding; this study characterizes its interaction in vivo in mice PMID: 28035745
    2. FVIIa-antithrombin but not FVIIa is a ligand for LRP1, and LRP1 contributes to the clearance of FVIIa-antithrombin in vivo PMID: 27614059
    3. FVIIa binding to EPCR leads to a barrier protective effect in vivo PMID: 24977291
    4. Murine FVIIa binds poorly to murine EPCR. PMID: 22370814
    5. GlycoPEGylated rFVIIa (N7-GP) has a prolonged hemostatic effect in hemophilic mice compared with rFVIIa PMID: 21366858
    6. Conclude that the fVII-targeted verteporfin photodynamic therapy that we report here is a novel and effective therapeutic with improved selectivity for the treatment of breast cancer. PMID: 20504328
    7. Recombinant FVIIa readily associates with the vascular endothelium and subsequently enters into extravascular spaces where it is likely to bind to tissue factor and is retained for extended time periods. PMID: 19943873
    8. true circadian rhythms for FVII were found PMID: 15604416
    9. Data suggest that long-term expression of murine activated factor VII is safe, but elevated levels cause premature mortality. PMID: 18398505
    10. FVIIa functions in the asthmatic response to an allergen by stimulating lung eosinophilia, airway hyperresponsiveness, and mucin production. PMID: 19286924
    11. Plasma elimination kinetics for factor VII are independent of its activation to factor VIIa and complex formation with plasma inhibitors. PMID: 19404533

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Peptidase S1 family
  • 組織特異性：
    Plasma and liver.
  • 數(shù)據(jù)庫鏈接：

    KEGG: mmu:14068

    STRING: 10090.ENSMUSP00000033820

    UniGene: Mm.4827



主站蜘蛛池模板： 粉嫩粉嫩的18在线观看| 女人高潮内射99精品| 伊人激情av一区二区三区| 国产成人免费97在线| 日韩av中文无码影院| 精品免费国产一区二区三区四区介绍| 成人免费无码大片a毛片抽搐色欲| 久久婷婷激情综合色综合俺也去| 三级成年网站在线观看级爱网| 久久99久久99久久综合| 精品人妻少妇一区二区三区| 日本大乳高潮视频在线观看| a毛看片免费观看视频| 精品无码乱码av| 亚洲精品综合欧美一区二区三区| 丰满熟妇人妻av无码区| 天天射寡妇射| 国产美女视频免费观看的网站| 亚洲精品无码久久久久秋霞| 一个人在线观看免费视频www| 色综合视频一区二区三区| 亚洲欧美日韩成人综合一区| 国产午夜福利精品一区| 无码少妇一区二区性色av| 国产 麻豆 日韩 欧美 久久| 成人一区二区免费中文字幕视频| 成·人免费午夜视频香蕉| 久久亚洲精品成人av| 一本久久a久久精品综合| 久久99亚洲精品久久久久| 拍真实国产伦偷精品| 人妻少妇被猛烈进入中文字幕| 午夜福利电影网站鲁片大全| 999精品无码a片在线1级| 国产口爆吞精在线视频2020版| 婷婷色香合缴缴情av第三区| 久久精品国产只有精品96| 水蜜桃亚洲一二三四在线| 欧美熟妇性开放| 99久久精品国产一区二区| 亚洲精品无播放器在线播放|