-
中文名稱:小鼠趨化因子配體17(CXCL17)酶聯免疫試劑盒
-
貨號:CSB-EL006246MO
-
規格:96T/48T
-
價格:¥3600/¥2500
-
其他:
產品詳情
-
產品描述:小鼠趨化因子配體17(CXCL17)酶聯免疫試劑盒(CSB-EL006246MO)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的CXCL17含量。CXCL17 是一種趨化因子。目前對它的研究顯示,其在免疫調節等方面有潛在作用。研究機制上,它可吸引特定免疫細胞,參與炎癥反應及腫瘤微環境調控等過程,不過對其具體作用路徑和分子機制還需進一步深入探索。試劑盒檢測范圍為37.5 pg/mL-2400 pg/mL,科研人員可將其應用于炎癥性疾病機制研究、免疫微環境分析或藥物干預模型中趨化因子動態變化的評估,為探索CXCL17在先天免疫調控、組織修復及病理狀態下的功能提供可靠工具。CXCL17作為新型趨化因子家族成員,在黏膜免疫調節及炎癥反應中發揮重要作用,尤其在呼吸道和消化道相關疾病模型中具有研究價值。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
-
別名:Cxcl17 ELISA kit; Vcc1C-X-C motif chemokine 17 ELISA kit; 6-Cys CXCL17 ELISA kit; 13.6 kDa protein ELISA kit; VEGF coregulated chemokine 1) [Cleaved into: 4-Cys CXCL17] ELISA kit
-
縮寫:CXCL17
-
Uniprot No.:
-
種屬:Mus musculus (Mouse)
-
樣本類型:serum, plasma, tissue homogenates
-
檢測范圍:37.5 pg/mL-2400 pg/mL
-
靈敏度:9.375 pg/mL
-
反應時間:1-5h
-
樣本體積:50-100ul
-
檢測波長:450 nm
-
研究領域:Immunology
-
測定原理:quantitative
-
測定方法:Sandwich
-
數據處理:
-
貨期:3-5 working days
引用文獻
- CXCL17 Attenuates Diesel Exhaust Emissions Exposure-Induced Lung Damage by Regulating Macrophage Function Y Yin,Toxics,2023
- CXCL17-derived CD11b+Gr-1+ myeloid-derived suppressor cells contribute to lung metastasis of breast cancer through platelet-derived growth factor-BB Hsu YL, et al,Breast Cancer Research,2019
相關產品
靶點詳情
-
功能:Chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions.
-
基因功能參考文獻:
- CXCL17 attenuates Imiquimod -induced psoriasis-like skin inflammation by recruiting myeloid-derived suppressor cells and regulatory T cells , which may be important for regulating excessive inflammation in psoriasis skin. PMID: 28389593
- CXCL17 is a novel macrophage chemoattractant that operates in mucosal tissues as a major regulator of inflammatory responses. PMID: 24973458
- These results suggest that aberrant expression of CXCL17 in tumor cells recruits immature myeloid-derived cells and promotes tumor progression through angiogenesis. PMID: 22952881
- VCC-1 plays a role in angiogenesis and possibly in the development of tumors in some tissue types[VCC-1] PMID: 16989774
-
亞細胞定位:Secreted.
-
蛋白家族:Intercrine alpha (chemokine CxC) family
-
組織特異性:Detected in lung, trachea, lung, tongue thyroid, submaxillary gland, epididymis, and uterus tissues and at a lower level in ovary, prostate and in intestinal tissues.
-
數據庫鏈接:
KEGG: mmu:232983
UniGene: Mm.10545
Most popular with customers
-
Human Transforming Growth factor β1,TGF-β1 ELISA kit
Detect Range: 23.5 pg/ml-1500 pg/ml
Sensitivity: 5.8 pg/ml
-
-
Mouse Tumor necrosis factor α,TNF-α ELISA Kit
Detect Range: 7.8 pg/ml-500 pg/ml
Sensitivity: 1.95 pg/ml
-
-
-
-
-