在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Mouse Secretoglobin family 3A member 2(SCGB3A2) ELISA kit

Mouse Secretoglobin family 3A member 2(SCGB3A2) ELISA kit

  • 中文名稱：
    小鼠分泌球蛋白家族3A成員2(SCGB3A2)酶聯免疫試劑盒
  • 貨號：
    CSB-EL020819MO
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產品詳情

  • 產品描述：
    小鼠分泌球蛋白家族3A成員2(SCGB3A2)酶聯免疫試劑盒（CSB-EL020819MO）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿、細胞裂解物樣本中的SCGB3A2含量。SCGB3A2（分泌性杯狀細胞相關蛋白 3A2）是重要的肺上皮細胞分泌蛋白。它常作為肺臟相關疾病的潛在靶點。研究機制方面，主要聚焦其在肺組織穩態維持、炎癥反應調控等過程中的作用，探索通過干預它來治療如肺纖維化等疾病。試劑盒檢測范圍為9.4 pg/mL-600 pg/mL，適用于小鼠模型中肺纖維化、哮喘等呼吸道疾病的分子機制探索、藥物干預效果評估及SCGB3A2表達調控研究，支持科研人員高效開展體外實驗。本產品僅限用于科學研究領域，不適用于其他用途。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    Scgb3a2 ELISA Kit; Pnsp1 ELISA Kit; Ugrp1 ELISA Kit; Secretoglobin family 3A member 2 ELISA Kit; Pneumo secretory protein 1 ELISA Kit; PnSP-1 ELISA Kit; Uteroglobin-related protein 1 ELISA Kit
  • 縮寫：
    SCGB3A2
  • Uniprot No.：
  • 種屬：
    Mus musculus (Mouse)
  • 樣本類型：
    serum, plasma, tissue homogenates, cell lysates
  • 檢測范圍：
    9.4 pg/mL-600 pg/mL
  • 靈敏度：
    2.35 pg/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Epigenetics and Nuclear Signaling
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of mouse SCGB3A2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　 Sample Serum(n=4)
    1:1 Average % 87
    Range % 82-91
    1:2 Average % 94
    Range % 89-98
    1:4 Average % 107
    Range % 103-110
    1:8 Average % 110
    Range % 104-114
  • 回收率：
    The recovery of mouse SCGB3A2 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample Type Average % Recovery Range
    Serum (n=5) 95 91-99
    EDTA plasma (n=4) 103 98-108
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/ml OD1 OD2 Average Corrected
    600 2.511 2.468 2.490 2.318
    300 1.672 1.699 1.686 1.514
    150 1.015 0.989 1.002 0.830
    75 0.594 0.586 0.590 0.418
    37.5 0.403 0.412 0.408 0.236
    18.75 0.292 0.289 0.291 0.119
    9.4 0.218 0.207 0.213 0.041
    0 0.171 0.173 0.172 　
  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

靶點詳情

  • 功能：
    Secreted cytokine-like protein. Binds to the scavenger receptor MARCO. Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram-negative bacterium P.aeruginosa, and yeast. Strongly inhibits phospholipase A2 (PLA2G1B) activity. Seems to have anti-inflammatory effects in respiratory epithelium. Also has anti-fibrotic activity in lung. May play a role in fetal lung development and maturation. Promotes branching morphogenesis during early stages of lung development. In the pituitary, may inhibit production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
  • 基因功能參考文獻：
    1. These results demonstrate that SCGB3A2 has an anti-inflammatory activity in the HDM-induced allergic airway inflammation model, in which SCGB3A2 may modulate the CCR4-CCL17 pathway. PMID: 27820933
    2. The pulmonary fibrosis in the Scgb3a2-null mice was more severe than the wild-type controls, thus establishing that SCGB3A2 has anti-fibrotic activity in vivo. PMID: 26559674
    3. SCGB3A2 is an anti-fibrotic agent, and suggest a possible therapeutic use of recombinant SCGB3A2 in the treatment of pulmonary fibrosis. PMID: 26178733
    4. The results indicate that the loss of SCGB3A2 function was influenced by a modifier gene(s) in mixed genetic background and suggest that SCGB3A2 has anti-inflammatory property. PMID: 25242865
    5. SCGB3A2 regulates FSH/LH production in the anterior pituitary lobe. PMID: 24514953
    6. Secretoglobin 3A2 suppresses bleomycin-induced pulmonary fibrosis by transforming growth factor beta signaling down-regulation PMID: 21478551
    7. Results demonstrate that SCGB3A2 is a useful marker for diagnosis of pulmonary tumors both in mice and humans. PMID: 20466451
    8. UGRP1 does not play a major role in the development of bronchial asthma in our Caucasian population. PMID: 12915772
    9. results demonstrate that interleukin-10 induces uteroglobin related protein 1(UGRP1) gene expression in lung epithelial cells through transcription factor T/EBP/NKX2.1-dependent pathway PMID: 15485815
    10. UGRP1 is downregulated in inflamed airways, such as allergic asthmatics. PMID: 15531759
    11. To assess a potential role for SCGB3A2 during early lung development, wild-type and Nkx2-1-null fetal lungs of early developmental stages were subjected to ex vivo organ culture in the presence of SCGB3A2. PMID: 18535256
    12. C/EBPalpha and C/EBPdelta have a role in the synergistic interaction with NKX2-1 in mouse Scgb3a2 gene transcription and lung development PMID: 18632661
    13. SCGB3A2 gene may contribute to Graves' disease susceptibility. PMID: 19126779

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Secretoglobin family, UGRP subfamily
  • 組織特異性：
    Highly expressed in lung where it localizes to epithelial cells of the trachea, bronchus and bronchioles (at protein level). Expressed in club/Clara cells of the bronchioles. Also detected in the anterior and posterior lobes of the pituitary gland where i
  • 數據庫鏈接：


主站蜘蛛池模板： 欧美多毛肥胖老妇做爰| 鲁一鲁一鲁一鲁一曰综合网| 99久久伊人精品综合观看| 粗大的内捧猛烈进出| 阳茎伸入女人阳道视频免费| 久久久久久久岛国免费观看 | 无码综合天天久久综合网色吧影院 | 婷婷五月日韩av永久免费| 国产精品第一区揄拍无码| 国产精品久久久| 亚洲日韩av无码一区二区三区| 亚洲大色堂人在线无码| 亚洲国产成人爱av网站| 成人性生交大片免费看中文| 国产精品成人久久电影| 奇米影视7777狠狠狠狠色| 天天躁人人躁人人躁狂躁| 国产一三四2021不卡| 免费观看啪啪黄的网站| 国产肉丝袜在线观看| 国产精品久久无码一区| 中文无码熟妇人妻av在线| 岛国av无码免费无禁网站麦芽| av无码久久久久不卡网站蜜桃| 久久综合五月丁香六月丁香| 日日av色欲香天天综合网| 国产亚洲精品久久久久久彩霞| 亚洲精品nv久久久久久久久久| 99久久精品国产一区二区三区| 久久久久久人妻毛片a片| 亚洲第一福利网站在线观看| 欧美成人在线视频| 中文字幕婷婷日韩欧美亚洲| 欧美高清大屁股xxxxx| 国产精品成人99一区无码| 亚洲aⅴ综合色区无码一区 | 亚洲成av人片在www| 久草热久草热线频97精品| 久久99热人妻偷产国产| 亚洲精品久久久久久久观小说| 欧美阿v高清资源在线|