在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Mouse Interleukin-36 beta(IL1F8) ELISA kit

  • 中文名稱:
    小鼠白介素36β(IL1F8)酶聯(lián)免疫試劑盒
  • 貨號:
    CSB-EL011619MO
  • 規(guī)格:
    96T/48T
  • 價格:
    ¥3600/¥2500
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品描述:
    小鼠白介素36β(IL1F8)酶聯(lián)免疫試劑盒(CSB-EL011619MO)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的IL1F8含量。IL1F8是一個靶點。它屬于IL-1家族成員,在免疫調(diào)節(jié)等過程發(fā)揮作用。研究機制方面,其參與多種信號通路調(diào)控,可能與炎癥相關(guān)疾病的發(fā)生發(fā)展有關(guān),目前針對它的研究有助于揭示疾病發(fā)病機制并為開發(fā)新療法提供方向。試劑盒檢測范圍為6.25 pg/mL-400 pg/mL,炎癥性疾病動物模型的病理機制探索、藥物干預(yù)后免疫因子動態(tài)監(jiān)測、基因編輯小鼠的免疫功能評估、免疫調(diào)節(jié)、皮膚炎癥及自身免疫性疾病的基礎(chǔ)研究本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名:
    Il36b ELISA Kit; Fil1e ELISA Kit; Il1f8 ELISA Kit; Interleukin-36 beta ELISA Kit; Interleukin-1 family member 8 ELISA Kit; IL-1F8 ELISA Kit
  • 縮寫:
    IL1F8
  • Uniprot No.:
  • 種屬:
    Mus musculus (Mouse)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    6.25 pg/mL-400 pg/mL
  • 靈敏度:
    1.56 pg/mL
  • 反應(yīng)時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領(lǐng)域:
    Immunology
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 數(shù)據(jù)處理:
  • 貨期:
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 功能:
    Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Stimulates production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes. Induces expression of a number of antimicrobial peptides including beta-defensin 4 and beta-defensin 103 as well as a number of matrix metalloproteases. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation. Induces the production of proinflammatory cytokines in bone marrow-derived dendritic cells (BMDCs), including IL-12, Il-1 beta, IL-6, TNF-alpha and IL-23, and activates p38 MAPK phosphorylation in BMDCs. Involved in dendritic cell maturation by stimulating the surface expression of CD80, CD86 and MHC class II. Induces the production of IFN-gamma, IL-4 and IL-17 by T-helper 1 (Th1) cells, cultured CD4(+) T-cells and splenocytes.
  • 基因功能參考文獻(xiàn):
    1. IL-36 promotes myeloid cell infiltration, activation, and inflammatory activity in skin PMID: 24829417
    2. Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity PMID: 21965679
    3. A critical role of IL-36R ligands in the interface between innate and adaptive immunity, leading to the stimulation of T helper responses. PMID: 21860022
    4. The interleukin-1-related cytokine IL-1F8 is expressed in glial cells, but fails to induce any of the classical IL-1 responses in glial cells. PMID: 15749024
  • 亞細(xì)胞定位:
    Cytoplasm. Secreted.
  • 蛋白家族:
    IL-1 family
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 欧美激情猛片xxxⅹ大3| 成人免费无码不卡毛片视频| 国产精品爽爽ⅴa在线观看| 亚洲伦无码中文字幕另类| 国产未成女一区二区| 成年美女黄网站18禁免费| 亚洲愉拍自拍欧美精品| 五月婷婷俺也去开心| 亚洲人成无码www久久久| 久久综合久久88中字幕文| 国产最新av在线播放不卡| 日韩亚洲国产激情一区浪潮av| 蜜桃视频一区二区三区在线观看 | 亚洲自偷自偷在线成人网址| 亚洲午夜成人精品无码app| 国产黑色丝袜视频在线观看网红| 国产成人无码一区二区在线播放| 国产精品自产拍在线观看| 亚洲国产精品综合久久网各| 国产福利姬喷水福利在线观看| 伊人久久大香线蕉综合狠狠| 国产午夜精品一区二区三区四区| 国产精品无码久久久久久久久久| 亚洲 另类 日韩 制服 无码| 人妻少妇无码中文幕久久| 国产丝袜视频一区二区三区| 人妻精油按摩bd高清中文字幕| 免费看又黄又爽又猛的视频软件| 国内精品综合久久久40p| 亚洲精品无码成人av电影网| 国产成人女人在线观看| 日韩无码电影| 岛国4k人妻一区二区三区| 亚洲热妇无码av在线播放| 亚洲成a人片在线观看无码| 免费无码国产v片在线观看| 国产亚洲产品影视在线产品| 国产成人免费高清直播| 亚洲aⅴ男人的天堂在线观看 | 欧洲性久久精品| 久久露脸国产精品|