在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Mouse β-hexosaminidase A,β-Hex A ELISA Kit

  • 中文名稱:
    小鼠β氨基己糖苷酶A(β-Hex A)酶聯免疫試劑盒
  • 貨號:
    CSB-E04818m
  • 規格:
    96T/48T
  • 價格:
    ¥3800/¥2500
  • 其他:

產品詳情

  • 產品描述:
    小鼠β氨基己糖苷酶A(β-Hex A)酶聯免疫試劑盒(CSB-E04818m)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的HEXA含量。HEXA是一種溶酶體酶,負責分解GM2神經節苷脂,維持細胞內環境穩定。其突變會導致GM2神經節苷脂在細胞內積累,引發泰薩二氏病等疾病。研究HEXA的機制,旨在開發治療相關遺傳性神經退行性疾病的藥物。試劑盒檢測范圍為3.12 μU/mL-200 μU/mL,適用于研究β-Hex A在代謝性疾病模型小鼠中的表達調控、基因敲除/過表達動物模型的酶活性驗證,以及藥物干預或病理條件下溶酶體功能的評估等科研場景。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
  • 別名:
    Hexa ELISA Kit; Beta-hexosaminidase subunit alpha ELISA Kit; EC 3.2.1.52 ELISA Kit; Beta-N-acetylhexosaminidase subunit alpha ELISA Kit; Hexosaminidase subunit A ELISA Kit; N-acetyl-beta-glucosaminidase subunit alpha ELISA Kit
  • 縮寫:
  • Uniprot No.:
  • 種屬:
    Mus musculus (Mouse)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    3.12 μU/mL-200 μU/mL
  • 靈敏度:
    0.78 μU/mL
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Neuroscience
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 精密度:
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度:
    To assess the linearity of the assay, samples were spiked with high concentrations of mouse β-Hex A in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:10Average %92
    Range %85-100
    1:20Average %93
    Range %87-98
    1:40Average %90
    Range %86-100
    1:80Average %90
    Range %86-98
  • 回收率:
    The recovery of mouse β-Hex A spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9789-101
    EDTA plasma (n=4)9592-98
  • 標準曲線:
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    μU/mlOD1OD2AverageCorrected
    2002.542 2.517 2.530 2.386
    1002.073 2.101 2.087 1.943
    501.452 1.464 1.458 1.314
    250.942 0.961 0.952 0.808
    12.50.416 0.402 0.409 0.265
    6.250.325 0.311 0.318 0.174
    3.120.247 0.237 0.242 0.098
    00.146 0.141 0.144
  • 數據處理:
  • 貨期:
    3-5 working days

產品評價

靶點詳情

  • 功能:
    Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme S is as active as the isozyme A on the anionic bis-sulfated glycans, the chondroitin-6-sulfate trisaccharide (C6S-3), and the dermatan sulfate pentasaccharide, and the sulfated glycosphingolipid SM2. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A.
  • 基因功能參考文獻:
    1. Neu4 is not the only sialidase contributing to the metabolic bypass in Hexa(-/-) mice. PMID: 20862357
  • 亞細胞定位:
    Lysosome.
  • 蛋白家族:
    Glycosyl hydrolase 20 family
  • 組織特異性:
    Ubiquitous. Most abundant in testis, adrenal, epididymis and heart. Low levels seen in the liver.
  • 數據庫鏈接:

    KEGG: mmu:15211

    STRING: 10090.ENSMUSP00000026262

    UniGene: Mm.2284



主站蜘蛛池模板: 52熟女露脸国语对白视频| 亚洲成a人v欧美综合天堂麻豆| 激情内射日本一区二区三区| 亚洲国产另类久久久精品黑人| 欧洲无码精品a码无人区| 久久精品免费一区二区三区| 无码成人精品区在线观看| 丰满岳跪趴高撅肥臀尤物在线观看| 欧美亚洲日本国产综合在线| 精品无码成人网站久久久久久 | 中文字幕亚洲码在线观看| 鲁大师在线视频播放免费观看| 成a人片亚洲日本久久| 欧美日韩亚洲tv不卡久久| 男人猛躁进女人免费播放| www一区二区www免费| 成片免费观看视频大全| 久拍国产在线观看| 欧美人与zoxxxx另类| 九九久久精品国产av片国产| 国产日产精品久久快鸭的功能介绍| 国产av麻豆天堂亚洲国产av刚刚碰| 怡红院av亚洲一区二区三区h| 国产精品毛片va一区二区三区| 日韩精品人妻系列一区二区三区| 国产多人群p刺激交换视频| 国产伦孑沙发午休精品| 亚洲gv猛男gv无码男同| 亚洲性人人天天夜夜摸18禁止| 奇米777四色影视在线看| 亚洲狠狠婷婷综合久久蜜芽| 国产成人综合在线女婷五月99播放| 亚洲乱码中文字幕小综合| 尤物色综合欧美五月俺也去 | 国产9 9在线 | 中文| 一区二区精品视频日本| 一边吃奶一边添p好爽高清视频| 不卡av电影在线| 国产精品久久久久秋霞鲁丝| 麻豆国产成人av高清在线观看| 欧美精品videosex极品|