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Monkey Insulin-like Growth Factor 1(IGF-1) ELISA KIT

  • 中文名稱:
    猴胰島素樣生長因子1(IGF-1)酶聯免疫試劑盒
  • 貨號:
    CSB-E13401Mk
  • 規格:
    96T/48T
  • 價格:
    ¥4200/¥3000
  • 其他:

產品詳情

  • 產品描述:
    猴胰島素樣生長因子1(IGF-1)酶聯免疫試劑盒(CSB-E13401Mk)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿樣本中的IGF-1含量。IGF-1即胰島素樣生長因子-1,在人體生長、發育及代謝調節等過程有重要作用。其研究機制方面,主要通過與受體結合激活下游信號通路,參與細胞增殖、分化等過程。研究該靶點對生長發育相關疾病、癌癥等的防治有潛在價值。試劑盒檢測范圍為62.5 ng/mL-4000 ng/mL,該產品可支持靈長類動物模型中IGF-1相關機制研究,例如探究生長激素軸調控、代謝性疾病模型建立、衰老相關研究或藥物干預實驗中的生物標志物動態監測,為發育生物學、內分泌學及營養學領域的科研工作者提供可靠工具。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
  • 別名:
    IGF1 ELISA Kit; Insulin-like growth factor I ELISA Kit; IGF-I ELISA Kit; Somatomedin ELISA Kit
  • 縮寫:
    IGF-1
  • Uniprot No.:
  • 種屬:
    Monkey
  • 樣本類型:
    serum, plasma
  • 檢測范圍:
    0.625 ng/ml-40 ng/ml
  • 靈敏度:
    0.312 ng/ml
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Signal Transduction
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 精密度:

  • 標準曲線:

  • 數據處理:
  • 貨期:
    3-5 working days

產品評價

平均分:
5.0分 - 1 個評價

樣品類型:血清

樣品信息:其他 猴

稀釋比:1:50

產品評價: 靈敏度良好,洗液可以考慮多一些

By 張老師

相關問答

 常見問題解答
Q:

Can you please let me know if this kit was tested for Rhesus Monkey?

A:
Thanks for your inquiry.
CSB-E13401Mk
This kit is designed against Rhesus Monkey.
We tested undiluted serum and plasma samples before and the test value is 1000ng/ml.
Pls let me know if you have any further questions. Thank you.
Q:

Thanks for your response.
What is the dynamic range for concentration in standard protein calibration curve?

A:
Thanks for your inquiry.
I will send you the manual by e-mail.
The detection range of this kit is 62.5 ng/ml-4000 ng/ml.Pls let me know if you have any further questions. Thank you.

靶點詳情

  • 功能:
    The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1.
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Insulin family


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