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中文名稱:猴胰島素樣生長因子1(IGF-1)酶聯免疫試劑盒
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貨號:CSB-E13401Mk
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規格:96T/48T
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價格:¥4200/¥3000
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其他:
產品詳情
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產品描述:猴胰島素樣生長因子1(IGF-1)酶聯免疫試劑盒(CSB-E13401Mk)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿樣本中的IGF-1含量。IGF-1即胰島素樣生長因子-1,在人體生長、發育及代謝調節等過程有重要作用。其研究機制方面,主要通過與受體結合激活下游信號通路,參與細胞增殖、分化等過程。研究該靶點對生長發育相關疾病、癌癥等的防治有潛在價值。試劑盒檢測范圍為62.5 ng/mL-4000 ng/mL,該產品可支持靈長類動物模型中IGF-1相關機制研究,例如探究生長激素軸調控、代謝性疾病模型建立、衰老相關研究或藥物干預實驗中的生物標志物動態監測,為發育生物學、內分泌學及營養學領域的科研工作者提供可靠工具。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
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別名:IGF1 ELISA Kit; Insulin-like growth factor I ELISA Kit; IGF-I ELISA Kit; Somatomedin ELISA Kit
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縮寫:IGF-1
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Uniprot No.:
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種屬:Monkey
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樣本類型:serum, plasma
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檢測范圍:0.625 ng/ml-40 ng/ml
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靈敏度:0.312 ng/ml
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反應時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領域:Signal Transduction
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測定原理:quantitative
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測定方法:Sandwich
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精密度:
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標準曲線:
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數據處理:
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貨期:3-5 working days
相關產品
相關問答
Can you please let me know if this kit was tested for Rhesus Monkey?
CSB-E13401Mk
This kit is designed against Rhesus Monkey.
We tested undiluted serum and plasma samples before and the test value is 1000ng/ml.
Pls let me know if you have any further questions. Thank you.
Thanks for your response.
What is the dynamic range for concentration in standard protein calibration curve?
I will send you the manual by e-mail.
The detection range of this kit is 62.5 ng/ml-4000 ng/ml.Pls let me know if you have any further questions. Thank you.
靶點詳情
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功能:The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1.
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亞細胞定位:Secreted.
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蛋白家族:Insulin family
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