在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Human melanin-concentrating hormone (PMCH) ELISA kit

Human melanin-concentrating hormone (PMCH) ELISA kit

  • 中文名稱：
    人黑色素濃縮激素(PMCH)酶聯免疫試劑盒
  • 貨號：
    CSB-EL018230HU
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產品詳情

  • 產品描述：
    人黑色素濃縮激素(PMCH)酶聯免疫試劑盒（CSB-EL018230HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的PMCH含量。PMCH即前黑素聚集激素，它是一種神經肽。在其與能量代謝、睡眠覺醒等生理過程相關。研究機制上，主要是通過與特定受體結合，激活細胞內信號通路來發揮作用，目前在肥胖、睡眠障礙等病癥的治療研究中受關注。試劑盒檢測范圍為15.6 pg/mL-1000 pg/mL，適用于探索PMCH在能量代謝調控、神經內分泌系統中的作用機制，或用于評估疾病模型、藥物干預實驗中的PMCH動態變化。該產品嚴格適配科研場景，為代謝性疾病、神經科學等領域的基礎研究提供可靠工具。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    PMCH ELISA Kit; MCHPro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid ELISA Kit; NGE ELISA Kit; Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine ELISA Kit; NEI ELISA Kit; Neuropeptide E-I); Melanin-concentrating hormone ELISA Kit; MCH)] ELISA Kit
  • 縮寫：
    PMCH
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    15.6 pg/mL-1000 pg/mL
  • 靈敏度：
    3.9 pg/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Neuroscience
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human PMCH in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　 Sample Serum(n=4)
    1:1 Average % 95
    Range % 90-100
    1:2 Average % 87
    Range % 83-91
    1:4 Average % 92
    Range % 88-96
    1:8 Average % 90
    Range % 85-94
  • 回收率：
    The recovery of human PMCH spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample Type Average % Recovery Range
    Serum (n=5) 100 95-104
    EDTA plasma (n=4) 84 80-88
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/ml OD1 OD2 Average Corrected
    1000 2.682 2.533 2.608 2.400
    500 2.040 1.946 1.993 1.785
    250 1.419 1.357 1.388 1.180
    125 0.927 0.975 0.951 0.743
    62.5 0.654 0.689 0.672 0.464
    31.2 0.408 0.392 0.400 0.192
    15.6 0.335 0.324 0.330 0.122
    0 0.204 0.211 0.208 　
  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

相關問答

■ 常見問題解答
Q:

你有EDTA血液中人血漿的參考范圍嗎?抗體的靶標是什么？

A:
一般情況下，我們檢測的是正常的血清和血漿樣本，沒有明顯的病理變化，具體的樣本檢測請咨詢我們。

靶點詳情

  • 功能：
    MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. May also have a role in spermatocyte differentiation.
  • 基因功能參考文獻：
    1. MCH is an anabolic neuropeptide with multiple and diverse physiological functions including a key role in energy homoeostasis; evidence suggests that, in the reproductive context, MCH is a modulator rather than a primary regulator. PMID: 23884861
    2. Cerebrospinal fluid (CSF) levels were measured in 33 patients with Alzheimer's disease (AD) and 33 healthy subjects, to investigate the role of MCH and HCRT-1 in AD. PMID: 23667582
    3. the changes in the levels of two hypothalamic neuropeptides, hypocretin-1 and melanin-concentrating hormone, measured in the human amygdala, are reported. PMID: 23462990
    4. Melanin-concentrating hormone (MCH) neurons of human hypothalamus, as well as the MCH neurons of mouse hypothalamus, contain IL-6Ralpha. PMID: 22295972
    5. PMCH mRNA expression level was increased 1.85 times (P < 0.01) in vitiligo uninvolved skin and 5.36 times (P < 0.01) in involved skin compared to healthy control skin. PMID: 20888736
    6. Melanin-concentrating hormone is expressed and functional in human skin PMID: 12176038
    7. RT-PCR analysis revealed a low expression of prepro-MCH and MCH receptor 1 (MCHR1) but not of MCHR2 transcript in tissular and peripheral blood immune cells PMID: 12220661
    8. Review. Melanin-concentrating hormone (MCH) is a cyclic neuropeptide, which centrally regulates food intake and stress. MCH-R1 antagonists can probe additional functions of the peptide, both in the brain and in the peripheral nervous system. PMID: 12885269
    9. Serum levels could serve as useful peripheral markers of changes in energy homeostasis. PMID: 15546902
    10. hMCH increased water intake independent of food intake. It significantly increased both sucrose solution and food intake. PMID: 15870910
    11. Single nucleotide polymorphisms in pro-melanin-concentrating hormone may be associated with obesity and a greater body mass index in olanzapine-treated schizophrenic patients PMID: 17541984
    12. expression of PMCH by activated Th2 cells in vivo may directly link allergic inflammation to energy homeostasis and may contribute to the association between asthma and obesity PMID: 17640905
    13. The total number of hypocretin-1 neurons was significantly reduced by 30% in HD brains (P = 0.015), while the total number of MCH neurons was not significantly altered (P = 0.100). PMID: 18498421
    14. MCH has a role in inflammatory processes in the intestine PMID: 18650383

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Melanin-concentrating hormone family
  • 組織特異性：
    Predominantly expressed in lateral hypothalamus, also detected in pallidum, neocortex and cerebellum. Also found in thymus, brown adipose tissue, duodenum and testis (spermatogonia, early spermatocytes and Sertoli cells). No expression in peripheral blood
  • 數據庫鏈接：

    HGNC: 9109

    OMIM: 176795

    KEGG: hsa:5367

    STRING: 9606.ENSP00000332225

    UniGene: Hs.707990



主站蜘蛛池模板： 少妇高清精品毛片在线视频| 四川丰满少妇被弄到高潮| 亚洲第一aaaaa片| 免费又黄又裸乳的视频| 国产精品高潮露脸在线观看| 亚洲国产精品无码中文lv| 久久av无码精品人妻糸列| 少妇厨房愉情理9仑片视频| 久久精品99av高久久精品| 国产精品久久久久久久伊一| 男人和女人做爽爽视频| 国产一区二区三区四区五区加勒比| 亚洲国产午夜精华无码福利| 成人看片黄a免费看| 欧美人与动另类xxxx| 女人被狂躁c到高潮视频| 中文字幕v亚洲日本在线| 国产av巨作丝袜秘书| 野花社区视频在线观看| 欧美日韩国产免费一区二区三区| 国产爆乳无码av在线播放| 亚洲综合激情七月婷婷| 久久超乳爆乳中文字幕| 中文字幕一区二区三区精华液| 国产成人无码av在线播放不卡| 亚洲日韩欧美一区二区三区| 久9re热视频这里只有精品| 国产爆乳无码视频在线观看| 国内精品自在自线视频| 日本公妇乱偷中文字幕| 2020久久香蕉国产线看观看| 国产高清-国产av| 国产亚洲曝欧美不卡精品| 乱色精品无码一区二区国产盗| 亲子乱av一区二区三区| 国产一本一道久久香蕉| www夜插内射视频网站| 亚洲一区二区女搞男| 亚洲精品入口一区二区乱麻豆精品| 大肉大捧一进一出好爽视频mba| 亚洲精品动漫免费二区|