在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Human melanin-concentrating hormone (PMCH) ELISA kit

Human melanin-concentrating hormone (PMCH) ELISA kit

  • 中文名稱：
    人黑色素濃縮激素(PMCH)酶聯免疫試劑盒
  • 貨號：
    CSB-EL018230HU
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產品詳情

  • 產品描述：
    人黑色素濃縮激素(PMCH)酶聯免疫試劑盒（CSB-EL018230HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的PMCH含量。PMCH即前黑素聚集激素，它是一種神經肽。在其與能量代謝、睡眠覺醒等生理過程相關。研究機制上，主要是通過與特定受體結合，激活細胞內信號通路來發揮作用，目前在肥胖、睡眠障礙等病癥的治療研究中受關注。試劑盒檢測范圍為15.6 pg/mL-1000 pg/mL，適用于探索PMCH在能量代謝調控、神經內分泌系統中的作用機制，或用于評估疾病模型、藥物干預實驗中的PMCH動態變化。該產品嚴格適配科研場景，為代謝性疾病、神經科學等領域的基礎研究提供可靠工具。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    PMCH ELISA Kit; MCHPro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid ELISA Kit; NGE ELISA Kit; Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine ELISA Kit; NEI ELISA Kit; Neuropeptide E-I); Melanin-concentrating hormone ELISA Kit; MCH)] ELISA Kit
  • 縮寫：
    PMCH
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    15.6 pg/mL-1000 pg/mL
  • 靈敏度：
    3.9 pg/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Neuroscience
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human PMCH in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　 Sample Serum(n=4)
    1:1 Average % 95
    Range % 90-100
    1:2 Average % 87
    Range % 83-91
    1:4 Average % 92
    Range % 88-96
    1:8 Average % 90
    Range % 85-94
  • 回收率：
    The recovery of human PMCH spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample Type Average % Recovery Range
    Serum (n=5) 100 95-104
    EDTA plasma (n=4) 84 80-88
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/ml OD1 OD2 Average Corrected
    1000 2.682 2.533 2.608 2.400
    500 2.040 1.946 1.993 1.785
    250 1.419 1.357 1.388 1.180
    125 0.927 0.975 0.951 0.743
    62.5 0.654 0.689 0.672 0.464
    31.2 0.408 0.392 0.400 0.192
    15.6 0.335 0.324 0.330 0.122
    0 0.204 0.211 0.208 　
  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

相關問答

■ 常見問題解答
Q:

你有EDTA血液中人血漿的參考范圍嗎?抗體的靶標是什么？

A:
一般情況下，我們檢測的是正常的血清和血漿樣本，沒有明顯的病理變化，具體的樣本檢測請咨詢我們。

靶點詳情

  • 功能：
    MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. May also have a role in spermatocyte differentiation.
  • 基因功能參考文獻：
    1. MCH is an anabolic neuropeptide with multiple and diverse physiological functions including a key role in energy homoeostasis; evidence suggests that, in the reproductive context, MCH is a modulator rather than a primary regulator. PMID: 23884861
    2. Cerebrospinal fluid (CSF) levels were measured in 33 patients with Alzheimer's disease (AD) and 33 healthy subjects, to investigate the role of MCH and HCRT-1 in AD. PMID: 23667582
    3. the changes in the levels of two hypothalamic neuropeptides, hypocretin-1 and melanin-concentrating hormone, measured in the human amygdala, are reported. PMID: 23462990
    4. Melanin-concentrating hormone (MCH) neurons of human hypothalamus, as well as the MCH neurons of mouse hypothalamus, contain IL-6Ralpha. PMID: 22295972
    5. PMCH mRNA expression level was increased 1.85 times (P < 0.01) in vitiligo uninvolved skin and 5.36 times (P < 0.01) in involved skin compared to healthy control skin. PMID: 20888736
    6. Melanin-concentrating hormone is expressed and functional in human skin PMID: 12176038
    7. RT-PCR analysis revealed a low expression of prepro-MCH and MCH receptor 1 (MCHR1) but not of MCHR2 transcript in tissular and peripheral blood immune cells PMID: 12220661
    8. Review. Melanin-concentrating hormone (MCH) is a cyclic neuropeptide, which centrally regulates food intake and stress. MCH-R1 antagonists can probe additional functions of the peptide, both in the brain and in the peripheral nervous system. PMID: 12885269
    9. Serum levels could serve as useful peripheral markers of changes in energy homeostasis. PMID: 15546902
    10. hMCH increased water intake independent of food intake. It significantly increased both sucrose solution and food intake. PMID: 15870910
    11. Single nucleotide polymorphisms in pro-melanin-concentrating hormone may be associated with obesity and a greater body mass index in olanzapine-treated schizophrenic patients PMID: 17541984
    12. expression of PMCH by activated Th2 cells in vivo may directly link allergic inflammation to energy homeostasis and may contribute to the association between asthma and obesity PMID: 17640905
    13. The total number of hypocretin-1 neurons was significantly reduced by 30% in HD brains (P = 0.015), while the total number of MCH neurons was not significantly altered (P = 0.100). PMID: 18498421
    14. MCH has a role in inflammatory processes in the intestine PMID: 18650383

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Melanin-concentrating hormone family
  • 組織特異性：
    Predominantly expressed in lateral hypothalamus, also detected in pallidum, neocortex and cerebellum. Also found in thymus, brown adipose tissue, duodenum and testis (spermatogonia, early spermatocytes and Sertoli cells). No expression in peripheral blood
  • 數據庫鏈接：

    HGNC: 9109

    OMIM: 176795

    KEGG: hsa:5367

    STRING: 9606.ENSP00000332225

    UniGene: Hs.707990



主站蜘蛛池模板： 久久国产免费观看精品a片| 亚洲一卡一卡二新区无人区| 国产福利高颜值在线观看 | 欧美人与动牲交zooz| 亚洲丁香五月天缴情综合| 99热这里有精品| 日日av色欲香天天综合网| 97无码免费人妻超级碰碰碰碰| 国产午夜福利久久精品| 免费人成在线观看视频播放| 欧美xxxx狂喷水| 亚洲成av人片在线观看一区二区三区| 欧美精品videossex少妇| 亚洲中文字幕无码一区二区三区| 无修无码h里番在线播放网站| 久久久精品人妻一区二区三区gv| 朝鲜女人大白屁股ass孕交| 国产精品美女久久久久久2018| 亚洲另类欧美综合在线| 老湿机香蕉久久久久久| 国内精品人妻无码久久久影院蜜桃| 国产精品乱码一区二区三| 亚洲中文字幕无码中文| 99热精国产这里只有精品| 色先锋av资源中文字幕| 色婷婷五月综合久久| 18禁无遮挡无码国产免费网站| 国产亚洲产品影市在线产品| 老妇肥熟凸凹丰满刺激| 国产在线高清亚洲精品二区| 成人奭片免费观看| 日日噜噜噜夜夜爽爽狠狠| 国产玉足脚交极品在线播放 | 亚洲国产午夜精华无码福利| 国模小黎自慰337p人体| .精品久久久麻豆国产精品| 亚洲福利国产网曝| 熟妇无码熟妇毛片| 野外做受三级视频| 亚洲国产综合无码一区| 国产精品青青青高清在线|