Human carbonhydrate antigen 19-9 (CA19-9) ELISA kit
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中文名稱:人糖類抗原19-9(CA19-9)酶聯(lián)免疫試劑盒
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貨號(hào):CSB-E04773h
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規(guī)格:96T/48T
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價(jià)格:¥3600/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:人糖類抗原19-9(CA19-9)酶聯(lián)免疫試劑盒(CSB-E04773h)為雙抗夾心法ELISA試劑盒,定量檢測(cè)血清、血漿樣本中的CA19-9含量。CA19-9是一種腫瘤相關(guān)碳水化合物抗原,是臨床常用的腫瘤標(biāo)志物。其背景在于可作為胰腺癌、膽管癌等消化系統(tǒng)惡性腫瘤的輔助診斷指標(biāo)。研究機(jī)制方面,主要是檢測(cè)血清中CA19-9水平,當(dāng)患有相關(guān)癌癥時(shí)其含量可能異常升高。試劑盒檢測(cè)范圍為10 U/mL-150 U/mL,靈敏度為3.8 U/mL。可用于腫瘤機(jī)制探索、藥物療效評(píng)估或生物標(biāo)志物相關(guān)性分析等科研場(chǎng)景本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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別名:CA199
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縮寫:CA19-9
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種屬:Homo sapiens (Human)
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樣本類型:serum, plasma
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檢測(cè)范圍:10 U/mL-150 U/mL
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靈敏度:3.8 U/mL
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反應(yīng)時(shí)間:1-5h
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樣本體積:50-100ul
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檢測(cè)波長(zhǎng):450 nm
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研究領(lǐng)域:Cancer
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測(cè)定原理:quantitative
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測(cè)定方法:Sandwich
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精密度:
Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<20%
Three samples of known concentration were tested in twenty assays to assess.
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線性度:
To assess the linearity of the assay, samples were spiked with high concentrations of human CA19-9 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
Sample
Serum(n=4)
1:1
Average %
96
Range %
90-110
1:2
Average %
89
Range %
85-99
1:4
Average %
93
Range %
87-101
1:8
Average %
95
Range %
89-98
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回收率:
The recovery of human CA19-9 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
Sample Type
Average % Recovery
Range
Serum (n=5)
97
93-100
EDTA plasma (n=4)
97
90-101
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標(biāo)準(zhǔn)曲線:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
U/ml
OD1
OD2
Average
150
2.045
2.011
2.028
100
1.292
1.300
1.296
40
0.728
0.735
0.732
10
0.304
0.306
0.305
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數(shù)據(jù)處理:
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貨期:3-5 working days
引用文獻(xiàn)
- Near-infrared photothermal immunoassay for pancreatic cancer biomarker CA 19-9 on a digital thermometer Xianlin Han, et al,Analytica Chimica Acta,2019
- Potential role of HE4 in multimodal screening for epithelial ovarian cancer. Urban N.et al,J Natl Cancer Inst.,2015
- Significance of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer patients receiving Bevacizumab: a single institution experience Baltru擰kevi?ien? E.et al,Acta medica Lituanica,2016
靶點(diǎn)詳情
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最新研究進(jìn)展:CA19-9是一種被廣泛用于胰腺癌診斷和監(jiān)測(cè)的糖蛋白。最近的研究表明,CA19-9可能有助于肝癌的診斷和治療。一項(xiàng)研究發(fā)現(xiàn),CA19-9陽(yáng)性的肝癌患者具有較高的肝癌特異性死亡率,這表明CA19-9可能是一種對(duì)肝癌患者預(yù)后具有潛在價(jià)值的生物標(biāo)志物。此外,一些研究還發(fā)現(xiàn),CA19-9的水平可以在肝癌治療過程中用于評(píng)估治療反應(yīng)。
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