在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Human Proteasome activator complex subunit 1(PSME1) ELISA kit

Human Proteasome activator complex subunit 1(PSME1) ELISA kit

  • 中文名稱：
    人蛋白酶體激活劑復合物亞基1(PSME1)酶聯免疫試劑盒
  • 貨號：
    CSB-EL018915HU
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產品詳情

  • 產品描述：
    人蛋白酶體激活劑復合物亞基1(PSME1)酶聯免疫試劑盒（CSB-EL018915HU）為雙抗夾心法ELISA試劑盒，定量檢測組織勻漿、細胞裂解物.樣本中的PSME1含量。PSME1是蛋白酶體復合物的必需亞基，參與蛋白質降解，尤其與細胞生長、周期調控、凋亡相關。其通過調節蛋白酶體裂解模式，增強I類結合肽產生，對免疫蛋白酶體組裝和抗原加工至關重要。試劑盒檢測范圍為0.19 ng/ml-12.5ng/ml，科研人員可通過該產品探索PSME1在腫瘤微環境調控、神經退行性疾病進程或自身免疫性疾病中的作用機制，也可用于評估藥物干預對蛋白酶體激活途徑的影響，為分子生物學研究、病理機制解析及靶向治療開發提供可靠的數據支持。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    11S regulator complex alpha subunit ELISA Kit; 11S regulator complex subunit alpha ELISA Kit; 29 kD MCP activator subunit ELISA Kit; 29kD MCP activator subunit ELISA Kit; Activator of multicatalytic protease subunit 1 ELISA Kit; IFI5111 ELISA Kit; IGUP I-5111 ELISA Kit; Interferon gamma IEF SSP 5111 ELISA Kit; Interferon gamma inducible protein 5111 ELISA Kit; Interferon gamma up regulated I 5111 protein ELISA Kit; Interferon gamma up-regulated I-5111 protein ELISA Kit; MGC8628 ELISA Kit; PA28a ELISA Kit; PA28alpha ELISA Kit; Proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) ELISA Kit; Proteasome activator 28 subunit alpha ELISA Kit; Proteasome activator complex subunit 1 ELISA Kit; Proteasome activator subunit 1 ELISA Kit; PSME1 ELISA Kit; PSME1_HUMAN ELISA Kit; REG-alpha ELISA Kit; REGalpha ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    tissue homogenates, cell lysates.
  • 檢測范圍：
    0.19 ng/ml-12.5ng/ml
  • 靈敏度：
    0.049 ng/ml
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Cell Biology
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：

    Intra-assay Precision (Precision within an assay): CV%<8%

    Three samples of known concentration were tested twenty times on one plate to assess.

    Inter-assay Precision (Precision between assays): CV%<10%

    Three samples of known concentration were tested in twenty assays to assess.

  • 標準曲線：

    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

    ng/ml

    OD1

    OD2

    Average

    Corrected

    12.5

    2.871

    2.977

    2.924

    2.832

    6.25

    2.339

    2.435

    2.387

    2.295

    3.125

    1.637

    1.583

    1.610

    1.518

    1.56

    0.845

    0.804

    0.825

    0.733

    0.78

    0.502

    0.515

    0.509

    0.417

    0.39

    0.250

    0.238

    0.244

    0.152

    0.19

    0.173

    0.179

    0.176

    0.084

    0

    0.093

    0.091

    0.092

    　

  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

靶點詳情

  • 功能：
    Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
  • 基因功能參考文獻：
    1. Such a modulation of proteasome activity is explained, at least in part, by the circadian expression of both Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and the proteasome activator PA28ab PMID: 26944190
    2. Results show that PA28alpha was found to be overexpressed in oral squamous cell carcinoma cell lines and tumor tissues. High expression of PA28alpha was significantly associated with recurrence and poorer overall survival. PMID: 26892607
    3. Constitutive expression of PA28 and ERAP1 in melanoma cells indicate that both interfere with MART-1(26-35) epitope generation even in the absence of IFN-gamma PMID: 26399368
    4. PA28 is a tumor marker and a potential target for therapeutic intervention in prostate cancer. PMID: 23918357
    5. Reduction in ATP levels triggers immunoproteasome activation by the 11S (PA28) regulator during early antiviral response mediated by IFNbeta in mouse pancreatic beta-cells. PMID: 23383295
    6. the first evidence of a novel ovarian cancer-specific marker PMID: 22532226
    7. PA28 selectively up-regulates the presentation of viral MHC class I epitopes and that down regulation PA28 in tumor cells results in impaired presentation of a human TRP2 tumor antigen. PMID: 12200048
    8. The relationship between anti-PA28alpha and Ki antibodies suggests the importance of an antigen-driven system in the induction of an autoimmune response to PA28 complex. PMID: 14760793
    9. DJ-1 and PA28alpha may have roles in the onset of hepatocarcinogenesis PMID: 17671684
    10. the 11S proteasome activator complex, Reg alpha fragment, may have a role in ovarian cancer PMID: 17939699
    11. bortezomib-adapted HL-60 cells showed increased expression and proteasome association of the 11S proteasome activator PMID: 19225532

    顯示更多

    收起更多

  • 蛋白家族：
    PA28 family
  • 數據庫鏈接：

    HGNC: 9568

    OMIM: 600654

    KEGG: hsa:5720

    STRING: 9606.ENSP00000372155

    UniGene: Hs.75348



主站蜘蛛池模板： 疯狂做受xxxx高潮不断| 免费人成视频网站在线观看18| 亚洲福利国产网曝| 永久免费观看黄网视频| 亚洲视频高清不卡在线观看 | 亚洲精品国产a久久久久久| 中文字幕无码视频专区| 黑人巨茎大战欧美白妇| 国产美女自卫慰水免费视频| 丰满少妇人妻hd高清大乳在线| 国产精品久久久久久熟妇吹潮软件| 亚洲日韩国产av无码无码精品| 解开人妻的裙子猛烈进入| 亚洲乱码日产精品bd在线看| 久久亚洲日韩av一区二区三区| 高清免费精品国自产拍| 欧美超级乱婬视频播放| 欧美人与动人物牲交免费观看久久| 免费人成在线观看网站品善网| 夜夜澡天天碰人人爱av| 国产av一区二区精品久久| 国产精品 视频一区 二区三区| 色一情一乱一伦一视频免费看| 色综合天天综合高清网国产在线| 无码人妻久久一区二区三区app| 午夜日本大胆裸艺术| 另类内射国产在线| 一本之道高清乱码久久久| 伊人久久大香线蕉综合bd高清| 久久人人97超碰国产公开| 毛多水多www偷窥小便| 国产免费无码一区二区| 精品一卡二卡三卡四卡网站| 高清国产av一区二区三区| 在线观看人成视频免费| 丰腴饱满的极品熟妇| 久青草国产97香蕉在线影院| 久久久精品人妻一区二区三区gv| 国产麻豆剧果冻传媒白晶晶| 无码人妻精品一区二区三区66| 国产美女自卫慰水免费视频|