在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯免疫試劑盒
  4. Human Mitochondrial import inner membrane translocase subunit TIM14(DNAJC19) ELISA kit

Human Mitochondrial import inner membrane translocase subunit TIM14(DNAJC19) ELISA kit

  • 中文名稱：
    人線粒體進口內膜轉位酶亞基TIM14(DNAJC19)酶聯免疫試劑盒
  • 貨號：
    CSB-EL007026HU
  • 規格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產品詳情

  • 產品描述：
    人線粒體進口內膜轉位酶亞基TIM14(DNAJC19)酶聯免疫試劑盒（CSB-EL007026HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿、細胞裂解物樣本中的DNAJC19含量。DNAJC19是一種基因，作為治療非小細胞肺癌的靶點。研究發現，該基因參與NSCLC細胞的增殖和遷移，通過抑制其表達可以有效降低腫瘤細胞的侵襲、遷移和生長能力，成為NSCLC患者的潛在治療靶標。試劑盒檢測范圍為28 pg/mL-1800 pg/mL，通過高特異性抗體對靶蛋白進行精準捕獲與信號放大，可為線粒體蛋白質轉運機制研究、疾病模型中線粒體功能障礙評估以及藥物干預效果分析提供可靠工具，廣泛應用于神經退行性疾病、心血管疾病等科研領域的分子機制探索及生物標志物定量分析。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    DnaJ (Hsp40) homolog; subfamily C; member 19 ELISA Kit; DnaJ homolog subfamily C member 19 ELISA Kit; DNAJC19 ELISA Kit; homolog of yeast TIM14 ELISA Kit; Mitochondrial import inner membrane translocase subunit TIM14 ELISA Kit; PAM18 ELISA Kit; TIM 14 ELISA Kit; TIM14 ELISA Kit; TIM14_HUMAN ELISA Kit; TIMM 14 ELISA Kit; TIMM14 ELISA Kit; translocase of the inner mitochondrial membrane 14 ELISA Kit; Translocase of the inner mitochondrial membrane 14; yeast homolog of ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates, cell lysates
  • 檢測范圍：
    28 pg/mL-1800 pg/mL
  • 靈敏度：
    7 pg/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Signal Transduction
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human DNAJC19 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:1Average %97
    Range %92-101
    1:2Average %86
    Range %81-90
    1:4Average %93
    Range %89-98
    1:8Average %90
    Range %85-94
  • 回收率：
    The recovery of human DNAJC19 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 10399-107
    EDTA plasma (n=4)9590-100
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected
    18002.656 2.719 2.688 2.579
    9002.287 2.172 2.230 2.121
    4501.653 1.707 1.680 1.571
    2251.135 1.071 1.103 0.994
    112.50.681 0.653 0.667 0.558
    560.374 0.362 0.368 0.259
    280.257 0.252 0.255 0.146
    00.112 0.105 0.109
  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

靶點詳情

  • 功能：
    Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling. May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity.
  • 基因功能參考文獻：
    1. Both DnaJC15 and DnaJC19 formed two distinct subcomplexes with Magmas at the import channel. PMID: 27330077
    2. The loss of DNAJC19/PHB complexes affects cardiolipin acylation and leads to the accumulation of cardiolipin species with altered acyl chains. PMID: 24856930
    3. A report of a new mutation in the human DNAJC19 gene that causes early onset dilated cardiomyopathy syndrome in two brothers of Finnish origin. PMID: 22797137
    4. The association of dilated cardiomyopathy with ataxia (DCMA) syndrome with a segment of 3q26.33 and the identification of a splice mutation in a novel gene DNAJC19 in DCMA patients. PMID: 16055927
    5. Dilated cardiomyopathy caused by homozygous mutations in a novel gene, DNAJC19, presumed to play a role in importation of mitochondrial proteins. PMID: 17244376

    顯示更多

    收起更多

  • 相關疾病：
    3-methylglutaconic aciduria 5 (MGA5)
  • 亞細胞定位：
    Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
  • 蛋白家族：
    TIM14 family
  • 組織特異性：
    Ubiquitously expressed.
  • 數據庫鏈接：

    HGNC: 30528

    OMIM: 608977

    KEGG: hsa:131118

    STRING: 9606.ENSP00000372005

    UniGene: Hs.230601



主站蜘蛛池模板： 国产亚洲日韩在线a不卡| 国产精品久久综合免费| 日韩成人无码v清免费| 亚洲人精品亚洲人成在线| 国产欧美在线观看不卡| 久久天天躁夜夜躁狠狠躁2022| 亚洲人成人伊人成综合网无码| 嫩草国产福利视频一区二区| 亚洲人成色77777在线观看| 久久精品黄aa片一区二区三区| 无修无码h里番在线播放网站| 国产一区二区亚洲精品 | 亚洲a综合一区二区三区| 久久婷婷五月综合鬼色| 国产精品美女一区二区三区| 欧美激情一区二区三区| 七妺福利精品导航大全| 可以免费观看的av毛片下载 | 日本在线观看| 中文www天堂| 日本japanese漂亮丰满| 亚洲男人的天堂在线播放| 日本五月天婷久久网站| 成人麻豆亚洲综合无码精品| 国产sp调教打屁股视频网站| 久久久国产精品| 8天堂资源在线| 丁香婷婷无码不卡在线| 欧美xxxx做受欧美人妖| 国产95在线 | 亚洲| 成人av片无码免费网站| 日韩人妻无码免费视频一二区| 久久精品日韩av无码| 超清av在线播放不卡无码 | 亚洲熟妇无码av不卡在线| 婷婷四房播播| 国产极品美女到高潮无套| 校花高潮抽搐冒白浆| 婷婷成人综合激情在线视频播放| 国产亚洲精品aaaaaaa片| 免费无码在线播放av |