在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Human Lysosomal protective protein(CTSA) ELISA kit

Human Lysosomal protective protein(CTSA) ELISA kit

  • 中文名稱：
    人溶酶體保護蛋白(CTSA)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-EL006184HU
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    人溶酶體保護蛋白(CTSA)酶聯(lián)免疫試劑盒（CSB-EL006184HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿、細胞裂解物樣本中的CTSA含量。試劑盒檢測范圍為15.6 pg/mL-1000 pg/mL，適用于基礎科研中探索CTSA在疾病模型中的表達變化、藥物干預對溶酶體功能的影響，或通過體液/組織樣本評估生物標志物水平；可為細胞生物學、病理機制研究及藥物開發(fā)提供可靠的工具支持。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    beta galactosidase 2 ELISA Kit; BETA GALACTOSIDASE PROTECTIVE PROTEIN ELISA Kit; beta-galactosidase 2 ELISA Kit; beta-galactosidase protective protein ELISA Kit; betagalactosidase 2 ELISA Kit; Carboxypeptidase C ELISA Kit; Carboxypeptidase L ELISA Kit; carboxypeptidase Y-like kininase ELISA Kit; Cathepsin A ELISA Kit; Ctsa ELISA Kit; deamidase ELISA Kit; EC 3.4.16.5 ELISA Kit; Glactosialidosis ELISA Kit; GLB2 ELISA Kit; Goldberg Syndrome ELISA Kit; GSL ELISA Kit; lysosomal carboxypeptidase A ELISA Kit; Lysosomal protective protein 20 kDa chain ELISA Kit; Lysosomal protective protein ELISA Kit; Lysosomal protective protein deficiency ELISA Kit; NEURAMINIDASE BETA GALACTOSIDASE EXPRESSION; NGBE ELISA Kit; Neuraminidase deficiency with beta-galactosidase deficiency ELISA Kit; NGBE ELISA Kit; OTTHUMP00000031778 ELISA Kit; OTTHUMP00000031781 ELISA Kit; PPCA ELISA Kit; PPCA deficiency ELISA Kit; PPGB ELISA Kit; PPGB_HUMAN ELISA Kit; Protective protein cathepsin A ELISA Kit; Protective protein for beta galactosidase ELISA Kit; Protective protein for beta-galactosidase ELISA Kit; Protective protein/cathepsin A deficiency ELISA Kit; urinary kininase ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates, cell lysates
  • 檢測范圍：
    15.6 pg/mL-1000 pg/mL
  • 靈敏度：
    3.9 pg/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Signal Transduction
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human CTSA in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:1Average %92
    Range %88-96
    1:2Average %89
    Range %85-93
    1:4Average %106
    Range %102-109
    1:8Average %94
    Range %87-98
  • 回收率：
    The recovery of human CTSA spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9185-96
    EDTA plasma (n=4)9692-99
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected
    10002.745 2.849 2.797 2.693
    5002.257 2.412 2.335 2.231
    2501.616 1.717 1.667 1.563
    1250.943 0.965 0.954 0.850
    62.50.547 0.524 0.536 0.432
    31.20.354 0.363 0.359 0.255
    15.60.245 0.254 0.250 0.146
    00.103 0.105 0.104
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

引用文獻

產(chǎn)品評價

靶點詳情

  • 功能：
    Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.
  • 基因功能參考文獻：
    1. The usefulness of modified U1 snRNA for rescue from exon 7 skipping caused by the IVS7 +3a>g mutation of the CTSA gene. PMID: 30010039
    2. The gene signature of OPA1, CTSA, NDUFA1, STK10 and PRDX1 was able to identify patients post-implant with a sensitivity of 91% and a specificity of 86% in discrimination between post-implant group and healthy controls. PMID: 27177495
    3. Galactosialidosis is a rare lysosomal storage disease caused by a combined deficiency of GM1 beta-galactosidase (beta-gal) and neuraminidase secondary to a defect of a lysosomal enzyme protective protein/cathepsin A (PPCA) and mutation in CTSA gene. PMID: 26259553
    4. Case Report: galactosialidosis with novel mutations of CTSA gene diagnosed using placental pathology. PMID: 25075748
    5. We identified compound heterozygous mutations in the CTSA gene, responsible for causing galactosialidosis PMID: 24769197
    6. correct nomenclature of mutations for this gene is discussed; clinical and mutational analyses of 4 cases with rare infantile form of galactosialidosis; identified 3 novel nucleotide changes, 2 resulting in missense mutations and the third, resulting in the p.Gln406* stop codon; complexity of the clinical phenotypes in GS reflects dual functions of PPCA/CTSA PMID: 23915561
    7. Catalytic function, tissue distribution and substrates of cathepsin A are discussed as well as inhibition of cathepsin A as an emerging strategy for the treatment of heart failure. PMID: 23495688
    8. The Cathepsin C releases the glycosidases from complexes formed with cathepsin A, and reinstates their activity. PMID: 22532132
    9. Our data suggest that CatA is involved in the C-terminal fine-tuning of antigenic T cell epitopes in human APC. PMID: 19954752
    10. mutations in early infantile galactosialidosis in two Dutch patients PMID: 12649068
    11. Increased activity of beta-galactosidase in the peritoneal fluid is associated with gynecologic cancers and pelvic inflammatory disease PMID: 15785934
    12. effects of GLB1, PPCA and NEU1 gene mutations on elastogenesis in skin fibroblasts PMID: 16538002
    13. Results describe the hydrodynamic properties of PPCA, NEU1, and a complex of the two proteins and identified multiple binding sites on both proteins. PMID: 19666471

    顯示更多

    收起更多

  • 相關疾病：
    Galactosialidosis (GSL)
  • 亞細胞定位：
    Lysosome.
  • 蛋白家族：
    Peptidase S10 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9251

    OMIM: 256540

    KEGG: hsa:5476

    STRING: 9606.ENSP00000361562

    UniGene: Hs.609336



主站蜘蛛池模板： 粉嫩虎白女毛片人体| 精品卡一卡二卡3卡高清乱码| 欧亚乱熟女一区二区在线| 2018av天堂在线视频精品观看| 天美传媒精品1区2区3区| 亚洲欧美国产国产一区二区三区| 日本黄页网站免费大全| 亚洲综合无码久久精品综合| 亚洲成aⅴ人片久青草影院| 色悠久久久久综合先锋影音下载| 377p欧洲日本亚洲大胆| 国产对白老熟女正在播放| 内射巨臀欧美在线视频| 中文字幕一区二区精品区| 国产欧美亚洲日韩图片| 国产精品无码一区二区三区电影| 女人和拘做爰正片视频| 成人午夜亚洲精品无码区毛片| 亚洲人成电影免费观看在线看| 极品少妇被猛的白浆直喷白浆| 日韩国产成人精品视频| 激情偷乱人伦小说视频| 国产产在线精品亚洲aavv| 国产精品久久一区二区三区| 国产精品香蕉在线观看| 2020年无码国产精品高清免费| 蜜桃av噜噜一区二区三区| 我和亲妺妺乱的性视频| 日韩成人无码毛片一区二区| 国产成人a无码短视频 | 西西4444www大胆无码| 少妇性l交大片| 一本久道久久综合久久爱| 中文字幕av无码专区第一页| 国产麻豆一精品一av一免费| 精品久久久久久无码不卡| 中日韩va无码中文字幕| 亚洲国产一区二区三区在线观看| 久久se精品一区精品二区| 国产99视频精品免费视频6| 国产精品久久久久久久久久红粉|