在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Human Lysosomal protective protein(CTSA) ELISA kit

Human Lysosomal protective protein(CTSA) ELISA kit

  • 中文名稱：
    人溶酶體保護蛋白(CTSA)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-EL006184HU
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    人溶酶體保護蛋白(CTSA)酶聯(lián)免疫試劑盒（CSB-EL006184HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿、細胞裂解物樣本中的CTSA含量。試劑盒檢測范圍為15.6 pg/mL-1000 pg/mL，適用于基礎科研中探索CTSA在疾病模型中的表達變化、藥物干預對溶酶體功能的影響，或通過體液/組織樣本評估生物標志物水平；可為細胞生物學、病理機制研究及藥物開發(fā)提供可靠的工具支持。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    beta galactosidase 2 ELISA Kit; BETA GALACTOSIDASE PROTECTIVE PROTEIN ELISA Kit; beta-galactosidase 2 ELISA Kit; beta-galactosidase protective protein ELISA Kit; betagalactosidase 2 ELISA Kit; Carboxypeptidase C ELISA Kit; Carboxypeptidase L ELISA Kit; carboxypeptidase Y-like kininase ELISA Kit; Cathepsin A ELISA Kit; Ctsa ELISA Kit; deamidase ELISA Kit; EC 3.4.16.5 ELISA Kit; Glactosialidosis ELISA Kit; GLB2 ELISA Kit; Goldberg Syndrome ELISA Kit; GSL ELISA Kit; lysosomal carboxypeptidase A ELISA Kit; Lysosomal protective protein 20 kDa chain ELISA Kit; Lysosomal protective protein ELISA Kit; Lysosomal protective protein deficiency ELISA Kit; NEURAMINIDASE BETA GALACTOSIDASE EXPRESSION; NGBE ELISA Kit; Neuraminidase deficiency with beta-galactosidase deficiency ELISA Kit; NGBE ELISA Kit; OTTHUMP00000031778 ELISA Kit; OTTHUMP00000031781 ELISA Kit; PPCA ELISA Kit; PPCA deficiency ELISA Kit; PPGB ELISA Kit; PPGB_HUMAN ELISA Kit; Protective protein cathepsin A ELISA Kit; Protective protein for beta galactosidase ELISA Kit; Protective protein for beta-galactosidase ELISA Kit; Protective protein/cathepsin A deficiency ELISA Kit; urinary kininase ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates, cell lysates
  • 檢測范圍：
    15.6 pg/mL-1000 pg/mL
  • 靈敏度：
    3.9 pg/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Signal Transduction
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human CTSA in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:1Average %92
    Range %88-96
    1:2Average %89
    Range %85-93
    1:4Average %106
    Range %102-109
    1:8Average %94
    Range %87-98
  • 回收率：
    The recovery of human CTSA spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9185-96
    EDTA plasma (n=4)9692-99
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected
    10002.745 2.849 2.797 2.693
    5002.257 2.412 2.335 2.231
    2501.616 1.717 1.667 1.563
    1250.943 0.965 0.954 0.850
    62.50.547 0.524 0.536 0.432
    31.20.354 0.363 0.359 0.255
    15.60.245 0.254 0.250 0.146
    00.103 0.105 0.104
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

引用文獻

產(chǎn)品評價

靶點詳情

  • 功能：
    Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.
  • 基因功能參考文獻：
    1. The usefulness of modified U1 snRNA for rescue from exon 7 skipping caused by the IVS7 +3a>g mutation of the CTSA gene. PMID: 30010039
    2. The gene signature of OPA1, CTSA, NDUFA1, STK10 and PRDX1 was able to identify patients post-implant with a sensitivity of 91% and a specificity of 86% in discrimination between post-implant group and healthy controls. PMID: 27177495
    3. Galactosialidosis is a rare lysosomal storage disease caused by a combined deficiency of GM1 beta-galactosidase (beta-gal) and neuraminidase secondary to a defect of a lysosomal enzyme protective protein/cathepsin A (PPCA) and mutation in CTSA gene. PMID: 26259553
    4. Case Report: galactosialidosis with novel mutations of CTSA gene diagnosed using placental pathology. PMID: 25075748
    5. We identified compound heterozygous mutations in the CTSA gene, responsible for causing galactosialidosis PMID: 24769197
    6. correct nomenclature of mutations for this gene is discussed; clinical and mutational analyses of 4 cases with rare infantile form of galactosialidosis; identified 3 novel nucleotide changes, 2 resulting in missense mutations and the third, resulting in the p.Gln406* stop codon; complexity of the clinical phenotypes in GS reflects dual functions of PPCA/CTSA PMID: 23915561
    7. Catalytic function, tissue distribution and substrates of cathepsin A are discussed as well as inhibition of cathepsin A as an emerging strategy for the treatment of heart failure. PMID: 23495688
    8. The Cathepsin C releases the glycosidases from complexes formed with cathepsin A, and reinstates their activity. PMID: 22532132
    9. Our data suggest that CatA is involved in the C-terminal fine-tuning of antigenic T cell epitopes in human APC. PMID: 19954752
    10. mutations in early infantile galactosialidosis in two Dutch patients PMID: 12649068
    11. Increased activity of beta-galactosidase in the peritoneal fluid is associated with gynecologic cancers and pelvic inflammatory disease PMID: 15785934
    12. effects of GLB1, PPCA and NEU1 gene mutations on elastogenesis in skin fibroblasts PMID: 16538002
    13. Results describe the hydrodynamic properties of PPCA, NEU1, and a complex of the two proteins and identified multiple binding sites on both proteins. PMID: 19666471

    顯示更多

    收起更多

  • 相關疾病：
    Galactosialidosis (GSL)
  • 亞細胞定位：
    Lysosome.
  • 蛋白家族：
    Peptidase S10 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9251

    OMIM: 256540

    KEGG: hsa:5476

    STRING: 9606.ENSP00000361562

    UniGene: Hs.609336



主站蜘蛛池模板： 久久久久久成人综合网| 都市激综合小说区另类区| 熟妇人妻激情偷爽文| av无码免费岛国动作片不卡| 国产成人精品无码免费看夜聊软件 | 老司机亚洲精品影院无码| 琪琪电影午夜理论片八戒八戒| 中文字幕日产熟女乱码| 免费国产在线精品一区不卡| 国产亚洲日韩av在线播放不卡| 暖暖视频日本| 日韩成人无码一区二区三区| 又黄又爽又色视频免费| 国产丝袜在线精品丝袜不卡| 真实国产乱子伦在线视频| 亚洲欧美日韩国产国产a| 肉色超薄丝袜脚交一区二区| 人妻丰满熟妞av无码区| 婷婷色婷婷开心五月| 日本看片一二三区高清| 婷婷激情综合色五月久久竹菊影视 | 337p粉嫩日本欧洲亚福利| 免费无码黄十八禁网站在线观看 | 东京热毛片无码dvd一二三区| 精品卡1卡2卡三卡免费网站| 精品熟女少妇av免费久久| 人人妻人人澡人人爽欧美一区 | 亚洲已满18点击进入在线观看| 人人妻人人爽人人爽| 欧美疯狂做受xxxx高潮| 性夜夜春夜夜爽aa片a| 欧美兽交xxxx×视频| 久久99精品久久久久久久不卡 | 精品国产成人高清在线观看| 熟妇人妻系列av无码一区二区| 浴室人妻的情欲hd三级| 国产成人影院一区二区三区| 纯肉无遮挡h肉动漫在线观看国产| 男人j进入女人j内部免费网站| 老司机午夜免费精品视频| 国内精品伊人久久久久影院对白|