Human Immunoglobulin D(IgD) ELISA Kit
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中文名稱:人免疫球蛋白D(IgD)酶聯(lián)免疫試劑盒
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貨號(hào):CSB-E15051h
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規(guī)格:96T/48T
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價(jià)格:¥3600/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:人免疫球蛋白D(IgD)酶聯(lián)免疫試劑盒(CSB-E15051h)為雙抗夾心法ELISA試劑盒,定量檢測(cè)血清、血漿、組織勻漿樣本中的IgD含量。IgD為免疫球蛋白D,是B細(xì)胞抗原受體的重要組成部分。其背景上在人體免疫系統(tǒng)中發(fā)揮關(guān)鍵作用。研究機(jī)制方面,它參與B細(xì)胞的活化、增殖和分化過(guò)程,在免疫應(yīng)答的啟動(dòng)和調(diào)節(jié)中意義重大,目前對(duì)其功能機(jī)制仍在進(jìn)一步深入研究。試劑盒檢測(cè)范圍為0.024 ng/mL-100 ng/mL,靈敏度為0.024 ng/mL。適用于免疫學(xué)基礎(chǔ)研究、炎癥機(jī)制探索或免疫相關(guān)疾病模型中IgD動(dòng)態(tài)變化的定量分析;為免疫調(diào)控研究、藥物效應(yīng)評(píng)估或生物標(biāo)志物篩選提供可靠數(shù)據(jù)支持本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書(shū)。
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別名:N/A
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縮寫(xiě):IgD
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種屬:Homo sapiens (Human)
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樣本類型:serum, plasma, tissue homogenates
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檢測(cè)范圍:0.024 ng/mL-100 ng/mL
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靈敏度:0.024 ng/mL
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反應(yīng)時(shí)間:1-5h
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樣本體積:50-100ul
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檢測(cè)波長(zhǎng):450 nm
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研究領(lǐng)域:Immunology
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測(cè)定原理:quantitative
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測(cè)定方法:Sandwich
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精密度:
Intra-assay Precision (Precision within an assay): CV%<8% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<10% Three samples of known concentration were tested in twenty assays to assess. -
線性度:
To assess the linearity of the assay, samples were spiked with high concentrations of human IgD in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:100 Average % 91 Range % 87-98 1:200 Average % 95 Range % 90-102 1:400 Average % 93 Range % 87-99 1:800 Average % 94 Range % 86-105 -
回收率:
The recovery of human IgD spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 90 85-96 EDTA plasma (n=4) 92 88-96 -
標(biāo)準(zhǔn)曲線:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. ng/ml OD1 OD2 Average Corrected 100 2.120 2.094 2.107 2.005 25 1.655 1.637 1.646 1.544 6.25 0.995 1.005 1.000 0.898 1.56 0.515 0.507 0.511 0.409 0.39 0.413 0.408 0.411 0.309 0.1 0.204 0.210 0.207 0.105 0.024 0.138 0.132 0.135 0.033 0 0.100 0.103 0.102 -
數(shù)據(jù)處理:
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貨期:3-5 working days
引用文獻(xiàn)
- Immunomodulatory constituents of human breast milk and immunity from bronchiolitis Chunyu Li.et al,Italian Journal of Pediatrics,2017
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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最新研究進(jìn)展:IgD是一種抗體分子,也是B淋巴細(xì)胞表面的一種受體。它在機(jī)體的免疫防御中起著重要作用,通過(guò)與抗原結(jié)合,誘導(dǎo)B細(xì)胞的激活和增殖,促進(jìn)免疫應(yīng)答的發(fā)生。最近的研究表明,IgD在機(jī)體的免疫調(diào)節(jié)中具有重要作用。一項(xiàng)研究發(fā)現(xiàn),在人類B細(xì)胞中,IgD能夠與TLR7相互作用,從而抑制炎癥介質(zhì)的產(chǎn)生。另一項(xiàng)研究發(fā)現(xiàn),在小鼠模型中,IgD能夠抑制胰島素樣生長(zhǎng)因子1(IGF1)的信號(hào)通路,從而降低肥胖相關(guān)的代謝疾病的發(fā)生率。
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