在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Human Chitinase-3-like protein 2(CHI3L2) ELISA kit

Human Chitinase-3-like protein 2(CHI3L2) ELISA kit

  • 中文名稱：
    人幾丁質酶3樣蛋白2(CHI3L2)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-EL005347HU
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    人幾丁質酶3樣蛋白2(CHI3L2)酶聯(lián)免疫試劑盒（CSB-EL005347HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的CHI3L2含量。CHI3L2是一種糖基水解酶家族成員，缺乏酶活性，通過結合多糖和細胞表面受體調控炎癥、組織重塑和腫瘤微環(huán)境。在關節(jié)炎、纖維化疾病和惡性腫瘤中高表達，是疾病進展的生物標志物和潛在治療靶點。試劑盒檢測范圍為0.78 ng/ml-50 ng/ml，該產(chǎn)品可為炎癥性疾病機制研究、纖維化模型評估或腫瘤微環(huán)境分析提供關鍵生物標志物檢測支持，特別適用于基礎醫(yī)學、免疫學及分子病理學領域的體外樣本檢測，幫助研究者探索CHI3L2在疾病發(fā)生發(fā)展中的調控作用。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    CH3L2_HUMAN ELISA Kit; CHI3L2 ELISA Kit; Chitinase 3 like 2 ELISA Kit; Chitinase-3-like protein 2 ELISA Kit; Chondrocyte protein 39 ELISA Kit; OTTHUMP00000014028 ELISA Kit; YKL 39 ELISA Kit; YKL-39 ELISA Kit; YKL39 ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    0.78 ng/ml-50 ng/ml
  • 靈敏度：
    0.19 ng/ml
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Stem Cells
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：

    Intra-assay Precision (Precision within an assay): CV%<8%

    Three samples of known concentration were tested twenty times on one plate to assess.

    Inter-assay Precision (Precision between assays): CV%<10%

    Three samples of known concentration were tested in twenty assays to assess.

  • 線性度：

    To assess the linearity of the assay, samples were spiked with high concentrations of human CHI3L2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

    　

    Sample

    Serum(n=4)

    1:1

    Average %

    87

    Range %

    81-91

    1:2

    Average %

    101

    Range %

    95-105

    1:4

    Average %

    102

    Range %

    98-109

    1:8

    Average %

    96

    Range %

    91-98

  • 回收率：

    The recovery of human CHI3L2 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

    Sample Type

    Average % Recovery

    Range

    Serum (n=5)

    94

    89-96

    EDTA plasma (n=4)

    96

    91-98

  • 標準曲線：

    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

    ng/ml

    OD1

    OD2

    Average

    Corrected

    50

    2.701

    2.688

    2.695

    2.582

    25

    2.344

    2.192

    2.268

    2.155

    12.5

    1.704

    1.729

    1.717

    1.604

    6.25

    1.151

    1.137

    1.144

    1.031

    3.125

    0.678

    0.699

    0.689

    0.576

    1.56

    0.388

    0.366

    0.377

    0.264

    0.78

    0.238

    0.241

    0.240

    0.127

    0

    0.115

    0.111

    0.113

    　

  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 功能：
    Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.
  • 基因功能參考文獻：
    1. This study shown that CHI3L2 is regulated differently in healthy and late onset Alzheimer"s disease brain depending on the sex. PMID: 27653898
    2. Structural analysis demonstrates that YKL-39 interacts with chitooligosaccharides through hydrogen bonds and hydrophobic interactions. Thermodynamic analysis indicates that binding of chitooligosaccharide to YKL-39 is mainly driven by enthalpy. PMID: 25477513
    3. These data suggest that hYKL-39 is a novel growth and differentiation factor involved in cartilage homeostasis. PMID: 23291184
    4. YKL-39 possesses a chitinase-like fold, but lacks key active-site residues required for catalysis. PMID: 22742450
    5. ERK1/2 phosphorylation by CHI3L2 inhibits cell mitogenesis and proliferation. PMID: 22211103

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Glycosyl hydrolase 18 family
  • 組織特異性：
    Highest expression in chondrocytes, followed by synoviocytes, lung and heart. Not detected in spleen, pancreas, and liver. May also be expressed in developing brain and placenta.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 1933

    OMIM: 601526

    KEGG: hsa:1117

    STRING: 9606.ENSP00000358763

    UniGene: Hs.514840



主站蜘蛛池模板： 国产精品亚洲а∨无码播放不卡| 少妇高潮喷潮久久久影院| 久久精品国产精品亚洲下载 | 亚洲精品国产精品乱码不卡| 在线观看国产成人av天堂| 日本精品一区二区三区四区| 国产区又黄又硬高潮的视频| 欧美日韩一本的免费高清视频| 亚洲伊人成综合网| 亚洲精品成人久久久| 亚洲-av-无限看| 丰满又黄又爽少妇毛片| 无尺码精品产品网站| 一区二区三区人妻无码| av无码电影一区二区三区| 成人特级毛片www免费版| 亚洲爆乳精品无码一区二区| 自愉自愉产区二十四区| 色猫咪免费人成网站在线观看| 色综合视频一区二区三区44| 无码国内精品人妻少妇蜜桃视频| 国产成人无码精品久久久免费 | 人妻体内射精一区二区| 亚洲αv无码一区二区三区四区| 伊人狼人大焦香久久网| 亚洲最大成人网站| 996久久国产精品线观看| 国产熟妇另类久久久久久| av无码欧洲亚洲电影网| 亚洲 自拍 另类 欧美 综合| 玩弄放荡人妇系列av在线网站| 国产精品18久久久久久欧美| 337p日本欧洲亚洲大胆裸体艺术| 无码国产69精品久久久久同性| 久久66热人妻偷产精品| 国产麻无矿码直接观看| 欧美性大战久久久久久| 国产视频亚洲精品视频| 国产精品一区二区 尿失禁| 日韩中文字幕免费视频| 午夜伦4480yy私人影院|